Background: Gallbladder diverticula have the appearance of hernia-like protrusions of the gallbladder wall. This disorder may not be diagnosed until surgically resected because it has no clinical significance unless there are associated diseases. Gallbladder pseudodiverticula have an acquired cause, multiple fundal lesions, an association with gallstones, internal saccular lesions without external hernia-like protrusions, and little to no smooth muscle in the gallbladder wall. Case Presentation: A 15-year-old boy in Saudi Arabia presented with right hypochondrial pain and dyspepsia. Imaging revealed innumerable gallstones in a distended gallbladder, indicative of chronic calculous cholecystitis. Elevated liver enzymes and coagulation abnormalities initially postponed surgery, but subsequent improvement allowed for laparoscopic cholecystectomy. Histopathological examination confirmed chronic calcular cholecystitis without malignancy. Conclusion: This case underscores the importance of recognizing and managing chronic calculous cholecystitis in adolescents promptly especially if associated with complication as pseudodiverticula. Successful treatment with laparoscopic cholecystectomy resulted in a positive outcome for the patient. Further research and case studies in this age group can enhance our understanding of the disease and optimize management strategies.

Although cadaver dissection and prosection are considered essential techniques for studying anatomy, their effectiveness is hindered by the use of flat, 2-D structures in didactic portions of anatomy courses. The limitations of this particular method can greatly hinder students' comprehension and grasp of anatomy, ultimately limiting the overall effectiveness and quality of the teaching and learning experience (TLE). In order to enhance the TLE and improve students' understanding of gross human anatomy, there are a variety of tools that can be utilized, including 3-D virtual anatomy applications and anatomical models. These resources provide a visual and interactive approach to learning, allowing for a more comprehensive understanding of the complex structures of the human body. The Anatomage, a virtual anatomy dissection table (VDT), is a highly sophisticated advancement that enables the dissection and prosection of the human body and its segments. The primary objective of this research project is to delve into integrating a VDT into a physical therapy anatomy course for a complex topic like head and neck, with the aim of enhancing the TLE and comprehension of anatomical concepts of said area. The methods encompass the inclusion of the VDT as an extra dissection table within the cadaver lab setting. Each group of scholars was given the responsibility to locate and study the assigned anatomical configurations and dissections on the VDT, specifically for their designated topic. Based on the results of our study, it can be inferred that there have been improvements in knowledge retention among students after the introduction of the VDT in the cadaver dissection segment of the course for head and neck. As a result of our research and analysis, we have come to the conclusion that the VDT is an exceptional tool that should be implemented in anatomy courses to help students understand intricate anatomical structures. The integration of the VDT is an essential and crucial step in the process of assimilating and applying human anatomy knowledge for students pursuing careers in the healthcare field.

Chronic hepatopathies are cosmopolitan disorders, the most common of which are chronic hepatitis and cirrhosis. Cirrhosis is a pathology of diverse etiologies characterized by diffuse disorganization of the normal hepatic structure due to hepatocyte destruction, with the appearance of regenerative nodules surrounded by fibrosis compressing the hepatic vascularization and causing portal hypertension. We report the case of a patient hospitalized in intensive care for decompensation of chronic hepathopathy during her 4th pregnancy, and we will describe the various consequences of pregnancy on this type of hepathopathy and vice versa via a detailed review of the literature.

Benign prostatic hyperplasia (BPH) is a non-malignant proliferation of prostatic cells resulting in glandular and stromal enlargement. It afflicts men in their advancing years resulting in lower urinary tract symptoms and alteration of quality of life (Qol). Diabetic patients seem to have larger prostate volumes than non-diabetic counterparts and this has formed an area of intense research interest. The aim of this work was to answer the research question: whether there is any significant difference in prostate volume between diabetic and non-diabetic men diagnosed with BPH. Materials and Methods: We retrospectively studied one hundred and thirty two (132) patients over a period of one year between October 2022 and September 2023 who presented in our Urology clinic for evaluation. Information were retrieved from their case notes and entered into a proforma. Data generated were analysed and used for this study. Results: Out of the 132 patients, diabetic men were 36(27.3%) while non-diabetics were 96 (72.7%). Mean overall age was 62.61±8.83 years, mean prostate volume was 59.53±45.50m/s and there was a significant mean difference in prostate volume between diabetic and non-diabetic populations (P=0.027). Conclusion: The research concluded that prostate volume in diabetic patients was higher than prostate volume in non-diabetic BPH patients.

Flaxseed, derived from the humble flax plant (Linum usitatissimum L.), has gained substantial recognition as a nutritional powerhouse in recent years. This abstract delves into the multifaceted attributes that make flaxseed an inimitable functional food for the human diet. With its rich history dating back to ancient civilizations, flaxseed has undergone a remarkable resurgence due to its exceptional health benefits. One of the standout features of flaxseed is its remarkable nutritional profile. It is renowned for being an excellent source of alpha-linolenic acid (ALA), a plant-based omega-3 fatty acid crucial for heart health. Furthermore, flaxseed is abundant in dietary fiber, lignans, and various essential vitamins and minerals, making it a versatile ingredient for promoting overall well-being. The advantages of flaxseed for health are numerous. It is known to reduce the risk of chronic diseases, including cardiovascular diseases, diabetes, and certain cancers. Its high fiber content aids in digestive health and weight management. Moreover, the lignans found in flaxseed exhibit powerful antioxidant properties, helping to combat oxidative stress and inflammation. Flaxseed's versatility extends to its culinary applications. It can be easily incorporated into a myriad of dishes, including smoothies, baked goods, and salads, enhancing both flavor and nutrition. In conclusion, flaxseed stands out as an inimitable functional food for the human diet, offering a potent combination of essential nutrients and health-promoting compounds. Incorporating this humble seed into daily nutrition holds the potential to transform health outcomes and contribute to a healthier, more vibrant future for individuals worldwide.

Hepatocellular carcinoma is considered one of the most threats to human health and is considered a fatal threat globally. Hepatocellular carcinoma is still a health challenge, and its incidence is growing worldwide. The role of non-coding miR-141 RNA in Hepatocellular carcinoma needs more investigations. Micro-RNA consists of 18-22 nucleotides. The role of miR-141 in hepatocellular carcinoma needs many investigations. The expression of miR-141 was elucidated in different cell lines including HepG2, HuH7, and the normal cell lines. The cell survival rate was detected in the case of untreated cells, control cells, and transfection by overexpression vector for miR-141, and anti-miR-141 transfection in the HepG2 cell line. The survival rate was at its highest level in the case of overexpressed miR-141 while it showed the least survival rate at anti-miR-141 transfection. Additionally, the effect of miR-141 was tested on both the IL-6 as an inflammatory cytokine and on TNF-α as well. In conclusion, miR-141 plays a pivotal role in HCC carcinogenesis.

Customer Relationship Management (CRM) is a new technique in marketing where the marketer tries to develop long term relationship with the customers to develop them as life time customers. This research checks the impact of customer relationship management activities on bank’s customer retention in The State Bank of India, Vikasnagar. For the purpose of study, a sampling analysis was conducted among (550) customers selected with the help of a structured questionnaire. (460) questionnaires were usable. Statistical answers give support on the high positive relationship between customer relationship management (CRM) and customer satisfaction. Thus, this paper aims to identify the reasons for the customers to prefer The State Bank of India at Vikasnagar. Further, this paper focuses the service provided by the staff in the bank. This paper is an attempt to find out CRM role in The State Bank of India at Vikasnagar and few recommendations were suggested from this study were to create an awareness of loan facility, internet banking and locker service.

Background: The definition of stillbirth recommended by WHO for international comparison is a baby born with no sign of Life at or after 28 weeks gestation. Aim of the study: The study aims to identify common risk factors associated with IUFD in Gaibandha 250 Bedded District Hospital, Gaibandha, Bangladesh. Methods: This Cross-sectional study was conducted at the Department of Gynecology & obstetrics, Gaibandha 250 Bedded District Hospital, Gaibandha, Bangladesh. participant was recruited retrospectively from medical records spanning one year from March, 2023 to Feb 2024. Result: The study involves 75 participants, predominantly aged 21-30 (57.90%) with primary education (55.00%). Most are housewives (65.50%) with average income. Pregnancy experience varies, with 2-3 pregnancies being the most common (36.40%). Most have normal systolic blood pressure (81.80%) and mild anemia (78.40%). Obstetric history includes abortion (18.20%) and IUFD (13 patients). Regular antenatal care (63.60%) is prevalent. Gestational age is >36 weeks for 37% of cases. Birth weights range primarily from 1-2kg (39%). Maternal factors contribute significantly to intrauterine fetal demise (IUFD), including chronic hypertension, pre-eclampsia, and premature rupture of membranes (PROM). Conclusion: The findings underscored the significant impact of maternal, fetal, and socio-demographic variables on IUFD incidence. Maternal factors such as hypertension and pre-eclampsia emerged as significant contributors, alongside fetal and cord-related issues. Socioeconomic disparities and inadequate antenatal care underscored the importance of holistic healthcare interventions to mitigate IUFD risks.

The study investigated effect of prolonged administration of Raphia Hookeri fruit pulp on oxidative stress markers in male wistar rats. A total of 24 male wistar rats of weight ranging from 200g to 350g were used. The rats divided in 4 groups, 3 groups administered orally with doses of extract at 500mg/kg, 1000mg/kg and 2000mg/kg body weight while control group fed with feed and water for 28 days. The animals sacrificed, samples taken, laboratory test done for stress markers. Statistical analysis done at p<0.05, values expressed as SEM. Results showed Malondialdehyde (MDA) values for group 2(0.77 ± 0.32nm/ml), group 3(1.79 ± 0.73nm/ml) and group 4(3.35 ± 0.20nm/ml) while for group 1(Control group) MDA value is 4.10 ± 0.3nm/ml. Mean values for Superoxide Dismutase (SOD) in treated groups (2-4) were 18.00 ± 1.0 units/ml, 29.50 ± 8.50units/ml, and 33.50 ± 37.25units/ml respectively and mean value for control group was 68.00 ± 4.0units/ml. Mean values for Glutathione Peroxidase (GPx) in test groups (2-4) were 53.50 ± 10.50ng/ml, 63.50 ± 5.50ng/ml, and 82.50 ± 6.50ng/ml respectively. GPx value for control group was 94.00 ± 3.00ng/ml. There was a graded increase from low dose to high dose. All treated groups indicated marginally (P>0.05) reduced values of Percentage change in body weight when compared to the control group (Group 1). Elevated levels of MDA indicates an increased oxidative stress and lipid. Higher levels of SOD and Gpx. This research demonstrates the ability of Raphia Hookeri fruit pulp to decrease oxidative stress hence regular consumption is recommended.

Objectives: To investigate the prevalence and mechanisms of atrial fibrillation (AF) among type 2 diabetes (T2D) patients. Methods: We conducted a thorough search of PubMed, SCOPUS, Web of Science, Google Scholar, and Science Direct to find pertinent literature. Rayyan QRCI was utilized during the entire process. Results: We included twelve studies with a total of 587,822 T2D patients and 299,957 (51%) were females. The prevalence of AF among T2D patients ranged from 0.2% to 41.63% with a total prevalence of 44936 (7.6%). The reported risk factors for developing AF among T2D patients were impaired glucose tolerance (IGT), men, obesity, elderly patients, those with lower socioeconomic backgrounds, those who currently smoked, people with reduced renal function, long-term BP fluctuation, and microvascular illness. Conclusion: Although the exact relationship between T2D and AF is still unclear, there is a significant correlation. Certain glycemic control studies indicate that therapeutic HbA1c levels in conjunction with well-controlled T2D do not significantly reduce the risk of new-onset AF in T2D patients. Further investigation is needed to fully comprehend the connection between T2D and AF. In the interim, healthcare professionals can treat people with T2D, AF, or possibly both illnesses at the same time according to accepted guidelines.

Introduction: Menstrual regulation, or the evacuation of the uterus of a woman at risk of being pregnant is done to ensure a state of no pregnancy, was introduced in Bangladesh in the 1970s in the context of a restrictive abortion law, in part to reduce maternal morbidity and mortality associated with unsafe abortion. Objectives: The study is designed to see the efficacy, safety and acceptability of uterine evacuation by medication using oral mifepristone and buccal misoprostol. Methods: All the patients attending the outpatient department. Of obstetrics & gynaecology in DNMCH during the study period seeking for MRM unwanted pregnancy. Of them 100 cases were selected purposively according to inclusion and exclusion criteria. Success was defined as medical abortion. Results: The oral misoprostol-mifepristone regimen, used by 100 women with a gestational age below 63 days, had a success rate of 92.0%. Ninety two percent patients were completely evacuated and Eight percent patients were incompletely evacuated. Conclusion: An evidence based regimen of 200 mg of mefipristone orally followed by home use of 800 mcg of buccal misoprostol 24hr later is safe and effective up to 9 weeks (63 days) of pregnancy. Further the need of aspiration for any reason was low and hospitalization was rare.

Objectives: The purpose of this systematic review is to investigate the risk factors and association of the incidence of diabetic kidney disease in adolescents with type 1 diabetes (T1D) patients. Methods: We conducted a thorough search of PubMed, SCOPUS, Web of Science, Google Scholar, and Science Direct to find pertinent literature. Rayyan QRCI was utilized during the entire process. Results: We included eight studies with a total of 11,468 T2D patients and 4966 (43.3%) were females. The available literature on the association between T1D and CKD among adolescents lacks epidemiological data on the prevalence and sex differences. Higher eGFR, diabetes duration, low C-peptide levels, glycemic control, age at a clinic visit, advanced glycation end products, and BMI were reported as significant risk factors for developing renal impairment in adolescents with T1D. Conclusion: The results of this research point to the necessity of a standardized screening procedure for the early identification and appropriate treatment of DKD. In order to provide an accurate assessment of this illness, methodological approaches should be taken into account. Furthermore, it's imperative to educate teenagers with T1D about the possibility of DKD, which can result in renal failure and even death. Future improvements in the quality of life for teenagers with T1D are anticipated as a result of this awareness.

This study was to determine the digitalizing cyber security for data management in higher education: Implication for Educational Management in Nigeria. Two research questions and hypotheses were formulated to guide the study. The population of this study comprises 4000 students from four tertiary instructions in Cross River State. The sampling technique employed by the researcher in the selection of the sample was the simple random sampling technique. The sample size selected for this study was 400 students in selected schools which represents 10 percent of the accessible population comprising of 200 males and 200 females. The questionnaire was designed to measure the two sub-independent variables. The reliability of the instrument was 0.85 reliability coefficient. Mean and standard deviation were used to answer the request questions. While Simple linear regression analysis statistical tool was used to test the null hypotheses that were formulated to guild the study at 0.05 level of significance. The findings of the study show that the educators’ lack of knowledge and expertise regarding cyberspace in tertiary institution significantly influence cyber security knowledge in data management in tertiary institution and Cyber security knowledge in data management in tertiary institution significantly reduces cyber-bully, online fraud, racial abuse, pornography and gambling among educators and students in tertiary institution in Cross River State, Nigeria. Based on the conclusion, it was recommended that tertiary institution management should formulate educational policies and curriculum the will help in addressing problems of cybercrime in schools. And students and educators should learn Cyberspace knowledge since it is very important in our day to day activities.

The agriculture sector in India has spent the last few decades primarily focusing on expanding agricultural output and enhancing food security. This approach included the following steps: first is, enhancing production through the use of high-quality seeds, agricultural chemicals, fertilizers, and irrigation. Second is, providing subsidies for farm inputs and paying fair prices for crops. Third is, Public investments in agriculture, and last is institutions that facilitate trade. Mid through the 1960s, the nation experienced a food shortage. In India, the green revolution overcome the path to address the food crisis that had persisted for the previous fifty years. India's population increased by 2.55 times while production of food increased by 3.7 times, which has made India a self-sufficient country in the food industry and able to export the net food to other countries. The strategy had no impact on the rise of farmers' income and had no provisions for their welfare. Several studies demonstrate that an increase in output should increase a farmer's income, but this was not always true. The Government of India (GoI) has announced in the union budget to double the income of farmers by 2022. Various grass root institutions are existing in India such as self-help groups, farmer's groups, farmer's interest groups, cooperatives, common interest groups, and Farmer Producer Organization (FPO). The GOI has suggested FPO as a tool, In order to mobilize the farmers and bring them under one umbrella to achieve the goal and double the farmers' income. Farmer Producer Organizations offer small and marginal farmers institutional support, assure a stable income for their agricultural output, and ultimately improve their standard of living. The main objective of this paper is to examine the structure of farmers' income in the country and how Farmer producer organizations empower the farmer's income to assess the possibility of enhancing the farmers’ income and discuss the FPO's tools for increasing the farmers’ incomes. The study is based on secondary data and the study is primarily exploratory. This paper addresses the issue of farmers' income and FPOs. This paper is based on 70th and 77th round NSSO Situation Assessment Surveys. The data pertains to the years 2012 and 2018-19. The information was gathered from different secondary sources, such as data on policies and other government sources, including NGOs, National and international management journals, and online sources are included. The study concludes that although boosting farmers' real earnings in six years is a challenging challenge, it may not be entirely unachievable if appropriate techniques are used. The study finds that increases over five to six years in nominal terms are already occurring. The instruments should be multifaceted and focus on increasing returns, lowering costs, and creating sustainable incomes while taking into account the dwindling natural resource base. For tracking the development, we should periodically have access to trustworthy income statistics. The income described in this paper is the gross cost of production. It can be concluded that FPOs form a core part of the strategy to sustain the life of small and marginal farmers out of poverty and enhance their income and competitiveness in agricultural markets. The expected result of this effort is to provide a single window for farmers to increase their income from farm produce through direct marketing and to gain collective bargaining power. So, the purpose of this study is to illustrate how smallholder farmers might raise their income through FPOs, which may help the farmers in doubling their income and empower them.

The COVID-19 pandemic exposed that we as a global society are not prepared enough to deal with food security amid unexpected situations. The global population is steadily increasing, posing significant challenges to food and feed security. With the world's population projected to reach 9.7 billion by 2050, finding alternative protein sources that are environmentally friendly and economically viable is becoming increasingly important. In recent years, there has been growing interest in using insect protein as a sustainable alternative to traditional meat production. This interest stems from several factors, including the increasing global population, the environmental impact of meat production, and the need for more sustainable practices in the food and feed industry. This paper will explore the potential advantages and limitations of edible insects as a source of protein for future food and feed security.