Reproductive process cannot be complete without hormone and if these hormones are not in the right proportion, then reproductive process could fail. Hormones are chemical substances produced by the endocrine gland and its physiological action is exerted on a target organ different from the secretion’s site. The aim is this study is to evaluate Effect of aqueous leave extract of D. alba ness (Thorn Apple) on gonadotropic hormones (FSH, LH) and prolactin following administration of MSG and clomid citrate in male wistar rats. The study involves 35 male wistar rats weighing between 130g to 160g. The animals were randomly selected into 7 with five animals per group. Each group received the following: group 1 10mls/kg of distil water, group 2 low dose of extract (1000mg/kg), group 3 high dose of extract(2000mg/kg), group 4 MSG 800mg/kg, group 5 clomid 50mg/kg, group 6 MSG + high dose of extract and group 7 clomid+ high dose of extract. Administration of extract was done through oral gavage for 21 days, thereafter, the animals were sacrificed on the 22nd day, and blood samples were collected for hormonal analysis. The results showed significant increase in serum levels of FSH and LH in the MSG group and decreased in FHS levels in all others treated groups when compared with control. The serum levels of FSH and LH rises when extract was co-administered with MSG. The serum levels of LH slightly increased when extract was co-administered with clomid serum levels of FSH do not increased when extract was co-administered with clomid. The statistical analysis was carried out using Statistical Package for Social Science (SPSS) version 23.

Introduction: The prevalence of glaucoma and cataracts has been rising. The crowded anterior segment architecture that results in appositional contact between the trabecular meshwork and the peripheral iris is the cause of primary angle closure. A technique to control intraocular pressure and deepen the anterior chamber is lens extraction. Objectives: To evaluate intraocular pressure changes in narrow angle eyes following phacoemulsification with intraocular lens implantation. Methodology: The study was carried out between March 2015 and August 2017 at Department of Ophthalmology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh on patients diagnosed with narrow-angle who also developed cataract. A narrow angle was defined as an anterior chamber angle grading of 2 or less on Shaffer grading in three or more quadrants. In accordance with the inclusion and exclusion criteria, a sample from the study population was drawn using the purposive type sampling technique. Participants in this prospective trial had foldable lens implantation after phacoemulsification surgery. Goldman applanation tonometry was done prior to surgery as well as on the tenth and thirtieth postoperative day. Results: The study included thirty eyes from 29 individuals, with a male to female ratio of 1:1 and an overall mean age of 62.03±8.95 years. Preoperative IOP was 13.66±1.69 mm Hg on average. The mean IOP at the 10th and 30th POD was 11.83±2.21 mm Hg and 11.00±2.07 mm Hg, respectively. At the final follow-up, the mean IOP drop was 2.66 mm Hg (p<0.05). Conclusion: In individuals with narrow angles, phacoemulsification combined with posterior chamber intraocular lens implantation can lower intraocular pressure. These results support the notion that phacoemulsification combined with foldable IOL implantation is a useful technique for reducing intraocular pressure.

Children's growth, health, and development depend on proper nutrition in infancy and early childhood. Worldwide, nursing is advantageous for both mother and child since breast milk is the best source of baby nourishment. This study examined mothers' knowledge and attitude about exclusive breast feeding’s nutritional benefits. A cross-sectional survey of 384 mothers was conducted in rural Igabi LGA. The data was acquired using structured questionnaires. SPSS 21 was used to enter and evaluate data. Chi-square determined categorical data associations. Statistical significance was set at p<0.05. By knowledge score, 13.80% of mothers had adequate knowledge, 51.04% intermediate, and 35.15% deficient. Attitude score: 63.80% of mothers were positive. Most mothers (52.5%) reported breast problems as major issues. A local language campaign to educate women about the nutritional benefits of exclusive breastfeeding and renewing the Baby-Friendly Hospital Policy can reduce child mortality, according to the study.

The transformation of terrorism from Al-Qaeda to the Islamic State (IS) has created new security challenges. This article examines the threats posed by these two groups by discussing their ideologies, structures and capabilities. Unlike local terrorist groups like the Afghan Taliban, the Islamic State and Al-Qaeda pose a global threat. The work looked at the origin of Al- Qaeda which cannot be separated from the soviet invasion of Afghanistan in 1979, and the objective of Al- Qaeda which main purpose is unifying and leading the jihad movement and providing its purpose and direction. The organization of Al- Qaeda was also discuss in this work, which is divided into four levels, which include, core Al- Qaeda, affiliated groups, allied groups and motivated persons and network. This work also assessed the impact of Al- Qaeda in global security, where some scholars argued that the group is not viable enough to pose global threat while others argued against it. On the other hand this work examined the origin of IS which started as a result of U.S military intervention in Iraq in 2003. It also examines resource base of IS and its objectives which is the destruction of the asymmetry status- quo existing for a long between Muslim countries and the Western allies. The impact and threat assessment of Al- Qaeda and IS on global security which we found out is that IS initially was fighting the near enemy in Iraqi and Syrian regimes, but latter changed its strategy by equally focusing on the “far enemy” as well, and manifested in its high profile attacks in Europe and other places beyond the Middle East. Lastly the researcher look at the differences between Al- Qaeda and IS in terms of their structure, brutality, popularity, conceptual difference etc. At the end, this paper recommends that a comprehensive global strategy is required to eradicate this growing menace of organized terrorism.

Doxorubicin-induced cardiotoxicity is the leading cause of morbidity and mortality among cancer survivors. The present study aimed to investigate the ameliorative effect of 5, 7-dihydroxyflavone (chrysin) against doxorubicin-induced cardiotoxicity in Wistar rats. Thirty-five adult male Wistar albino rats were randomly allocated into seven groups (n = 5 each) which consisted of normal control (group 1) receiving phosphate buffer saline (0.4 ml), positive control (Group 2) received 2mg\kg of doxorubicin (DOX) through an intraperitoneal route once weekly for 21 days, chrysin low dose and chrysin high dose (Group 3 and 4) received oral administration of chrysin 50&100mg/kg for 21 days, chrysin low dose and DOX, chrysin medium dose and DOX and chrysin high dose and DOX(group 5, 6, and 7) received 2mg/kg of DOX once weekly with 50, 100 and 150mg/kg of chrysin for 21 days. Significant elevations in cardiac troponin I (cTnI) and histological lesions, which corresponded with oxidative stress, inflammation, apoptotic indicators, and cardiotoxicity when compared to controls, were indicative of DOX-induced cardiotoxicity. Malondialdehyde (MDA), a sign of oxidative stress, SOD, CPK (creatinine phosphokinase), TBARS (thiobarbituric acid reactive substance), and CAT (catalase) were also elevated in the DOX group. The DOX group also had increased levels of cardiac inflammatory markers, including as interleukin-1 (IL-1), interleukin-6 (IL-6), and the apoptotic marker caspase-3. 5, 7-dihydroxyflavone (chrysin) significantly mitigated, but did not entirely reverse, the cardiotoxicity caused by DOX by reducing the histopathological scores of cardiomyopathies and lowering cTnI in comparison to the DOX group. Additionally, chrysin reduced MDA to substantially similar levels as the control. Following chrysin administration, significant decreases in IL-1, IL-6, and caspase-3 were also seen in comparison to the DOX-only group. All things considered, these findings point to chrysin's protective action against DOX-induced cardiotoxicity, which may have been rendered possible by oxidative stress, inflammatory, and apoptotic suppression.

Since 2018, are still disparities in the research results on items, prices, locations, promotions, people, processes, and physical evidence associated with customer loyalty based on the marketing mix and customer or patient loyalty. This study’s compares the theory and practice concerning the effect of marketing mix to outpatients’ loyalty. Hajj Hospital is currently experiencing a drop in the number of patients though numerous promotional efforts have been made, particularly during the COVID-19 pandemic. It is anticipated that the marketing mix will enhance consumer views of a product’s quality, as measured by consumers’ evaluations of the product. If the consumer perceives that the hospital provides high-quality services, the hospital’s image will be positive; this condition might boost customer or patient satisfaction. This study aims to determine which element of the marketing mix has the most significant impact on patient loyalty at Hajj Hospital. This study used a quantitative cross-sectional design approach, with 100 outpatient samples, and was analysed using SPSS. It was discovered that additional studies incorporated planning, control, monitoring, and evaluation into the marketing mix, utilising longitudinal studies or interventions for healthcare professionals that provide services to patients.

Background: Nursing students often struggle to maintain their health due to the rigorous demands of their curriculum, which frequently involves long hours of clinical work and exposure to stressful environments. Objective: This research study sought to investigate the effectiveness of a health promotion program based on Pender's Health Promotion Model (HPM) for nursing students with chronic illnesses. Methods: The study utilized a quasi-experimental design, including 105 nursing students from several institutions—55 participants belonging to an experimental group and 50 in the control group. To determine the students' quality of well-being prior- and post-treatment/phases, researchers monitored their health behaviors utilizing the Health-Promoting Lifestyle Profile II (HPLP-II) survey tool. The program included educational activities designed around coping with chronic diseases such as nutritional counseling or exercise planning also practical tools like stress management protocols/particulars along with peer support constructs/frameworks as key components in addressing adverse effects associated with such conditions. Results: Based on the results of the paired t-tests, a significant increase in HPLP-II scores was identified after the intervention in those assigned to the experimental group. Furthermore, an independent t-test highlighted that a significant difference existed between the average HPLP-II score for experimental and control groups. Discussion: These findings were scrutinized within Pender's Health Promotion Model framework to identify which aspects of the intervention contributed most efficiently to improved health behaviors and resultant outcomes. Conclusion: This research study established compelling evidence which supports the utilization of Pender's Health Promotion Model in improving health-promoting behaviors among nursing learners with chronic ailments. This finding could help nursing educators and healthcare professionals to outline interventions for this particular demographic group.

Corporate Social Responsibility (CSR) report is an effective way to promote the management of social responsibility and strengthen internal and external communication. CEO Statement, as the initial and prominent section in CSR reports, can give readers an overview of the whole reports. This paper selects Huawei and Apple as the data source and downloads the CEO statements in CSR reports from the official websites between 2017 and 2021 and build two corpora. The author uses Fairclough’s three-dimensional critical discourse analysis (CDA) mode as framework to analyze text, discourse practice and social practice of the CEO statements. By comparative analysis of CEO statements in Huawei and Apple CSR reports, we can find different features caused by different cultures. The study will provide practical suggestions for Chinese companies when compiling overseas CSR reports.

Sunflower (Helianthus annuus L.) is an important oilseed crop. It is grown for vegetable and industrial oils in the world. Sunflower oil is considered to be of supreme quality. The Production, productivity and area coverage of sunflower in Ethiopia is low and below the world average due to different reasons. Sunflower can contribute a big share in improving local edible oil production due to its short interval for maturity, high oil contents, better fitting in the cropping pattern, tolerance to drought and its high yield potential. Therefore, this study was conducted to quantify genetic variability of fourteen qualitative traits using Shannon-waver diversity index. A total of 220 genotypes including checks varieties were evaluated in 2020/21 main cropping season at Holeta, Ethiopia. Alpha lattice design was used with two replications and eleven blocks were nested within a replication. Based on fourteen qualitative traits significant variability or dissimilarity was observed among Sunflower genotypes. Analysis of Shannon-waver diversity index shows that H' values ranges from ~0.075 for leaf arrangement to ~0.99 for bract shape at the back of sunflower head. This shows that there is considerable diversity among the studied genotypes for the qualitative traits which can have good indications and amplification during selections of genotypes in sunflower improvement either ornamental type, confectionery or oil type sunflower.

Padayachee and Van Wyk in 1987 first documented the case of Glandular odontogenic cyst (GOC) and regarded this as ‘sialo-odontogenic cyst’ they published two cases that mimicked botryoid odontogenic cyst and the central mucoepidermoid tumor of jaws. Glandular odontogenic cyst (GOC) is counted as infrequent developmental odontogenic cyst of jaw that has the incidence of 0.012 to 1.3% only GOC is very rare with only 111 cases have been documented in the English literate till date. This case report in unique as this patient presented with the painless swelling in maxillary anterior region.

Over the centuries, with the development of economy, the excessive interference of human activities on the natural environment has caused profound changes in the earth's ecosystem. Under a White Sky: the Nature of the Future by American environmental journalist Elizabeth Kolbert is based on the relationship between man and nature, focusing on climate change. This article is based on the first part of chapter 1 of this book which describes the author's field investigation of river pollution in the United States, carp invasion of hydrological system and control measures. The paper hopes that more readers will recognize the destruction that human activities have caused to the Earth's ecosystem, and awaken more people's awareness of respecting nature and protecting ecology. Under the guidance of relevance translation theory, the author takes the optimal relevance principle as the translation criterion. Based on the cognitive context of the target audience, the translator adopts some translation skills including adding comments, meaning extension, part of speech conversion, division and combination, and word order adjustment, which will make the translation readable and in line with the Chinese language norms and expression habits.

Children frequently become victims of "Hurried Child Syndrome," a syndrome marked by over-scheduling, academic pressure, and the intrusion of digital devices in an ever-faster-paced society. The causes and effects of Hurried Child Syndrome are explored in this review article, which also highlights the harm that this condition does on children's physical and mental health. The article also covers potential remedies to lessen the effects of this illness, highlighting the value of parental education, limited screen time, and balanced scheduling. By tackling these problems, we hope to offer a thorough explanation of Hurried Child Syndrome, its causes, and methods for promoting happier, healthier childhoods.

The molecular epigenetics study in the plants plays a vital role in plant gene regulations, since the early descriptions of the non-Mendelians plant-based gene activities to pivotal detections of chromatin amending proteins necessary for plant growth and the RNAs which facilitates the silencing of genes in human and in the eukaryotes. Different factors playing important role in gene regulation in plants through cellular signaling pathways. Different genes show over expression and repression in response to different conditions in plants as a result of environmental stresses. While on the other hand, plants have haploid (gametophyte) development stage which occurs after meiosis and before fertilization. Genomic screening in Arabidopsis thaliana, the model plant, have been mainly worthwhile, yielding more than one hundred and thirty epigenetic regulators so far. The major contribution of plant science to current global hot problems like sustainability and climate change makes the expansion of plant science research capacity crucial. The objective is to highlight that reflect these developments in the creation of new biotechnological tools (NBTs) and the creative uses of plant genetic engineering. Studies that concentrate on the creation of NBT for resistant or previously non-transformable species to enable the unlocking of these species' biology are of great relevance to this collection. In addition, the use of cutting-edge genetic engineering techniques such as genome/gene editing and protein-domain specific technology (such as K-Domain technology).

Expectant fathers who suffer from Couvade syndrome, also known as sympathetic pregnancy, are experiencing a variety of physical and psychological symptoms that are comparable to those of their pregnant partners. It is an intriguing and comparatively unknown condition. This review article offers a comprehensive analysis of Couvade syndrome, including information on its classification, prevalence, particular causes, management strategies, prognosis, prevention, and prospects for alternative treatment techniques. Our goal is to better understand, support, and communicate with pregnant couples by exploring this unusual and fascinating situation.

Background: Background: Phytochemicals are plant bioactive compounds that are produced for their protection with some having medicinal value. Craterostigma plantagineum hoscht is a plant that is purported to have medicinal value and is used for treatment of pain, liver and diarrheal ailments. Extensive researches on phytochemicals present in Craterostigma plantagineum hoscht are missing. The aim of this study was to determine qualitative phytochemicals yield in ethanol and aqueous extracts of Craterostigma plantagineum hoscht. Materials and methods: Craterostigma plantagineum hoscht was harvested and allowed to air dry for one month. Grinding into powder form later followed this. Solvents used included 70% ethanol and distilled water. 500mg of Craterostigma plantagineum ground powder was soaked in 70% ethanol for 48 hours, filtered and vaporized in rotary evaporator. Aqueous extraction involved soaking of 500mg of ground powder in 250 millilitre distilled water, set in a shaker for 2 days, filtered, deep frozen for 48 hours and finally freeze dried for 72 hour. Chemicals used to test phytochemicals included 1% gelatin, chloroform, ferric chloride, sulphuric acid, lead acetate solution, magnesium turnings, 10% sodium chloride, acetic anhydride, Mayer’s reagent, ammonia and hydrochloric acid. Results: The yield included flavonoids, Saponins, tannins, cardiac glycosides, phenols, anthraquinones, alkaloids, terpenoids and sterols. Tannins, anthraquinones, flavonoids, sterols, cardiac glycosides, Saponins, and phenols were highly extracted in ethanol while aqueous extract yielded more alkaloids and terpenoids. Conclusion and recommendations: Ethanol extraction yielded more phytochemicals than aqueous. Nonetheless, some phytochemicals were better extracted in ethanol while others in aqueous making the choice of extraction method dependent on the phytochemical of interest.