Triple-negative breast cancer (estrogen receptor negative, progesterone receptor negative and HER2 negative) is a particularly high-risk breast cancer which does not receive specific therapy targeting these proteins. We report the case of a 23-year-old patient diagnosed with triple-negative breast cancer of the left breast with a family history of breast cancer and carrying a BRCA1 mutation. The classification of breast cancer based on genomic data is required to allow us to optimize therapies and improve the management of breast cancer patients.

Microteaching is an innovative educational method that began to be applied almost fifty years ago in teachers’ education and training, with its application subsequently expanding to other professional environments. This paper focuses on the study of the role and application of microteaching and attempts to demonstrate its value and importance mainly concerning candidate and serving teachers’ education and training. This article initially presents the definition, the object, the stages, and the scientific foundation of the method under discussion. Then, general information is provided for the application of microteaching both in Greece and internationally. Finally, the value of microteaching, its importance, and its contribution, especially in teacher education and training, are analyzed and discussed.

The study shows the evaluation of serum triglycerides. Triglycerides are the main constituents of body fats acids. The study was held in pankshin in plateau state. The distribution shows 5(5%) of the adults have 141-164mg/dL, 6(6.0%) of adults have 40-140mg/dL and the remaining 89 (89.0%) were above 165mg/dL. This clearly shows that most of the adults within Pankshin town have high triglycerides. The table presented results of serum triglycerides based on age ranges which 52 adults that were below 50 years were examined which 6(6.0%) were normal, 39(39.0%) have high serum triglycerides, 7(7.0%) have low triglycerides. A total number of 48 adults where above 50 years were examined which 5(5.0%) have normal serum triglycerides, 33(33.0%) have high serum triglycerides and the remaining 10(10.0%) have low triglycerides. This implies that most adults below 50 years have high triglycerides than others above 50 years. The table presented 41 males were sampled in this study which 6 (6.0%) of the male were normal of serum triglycerides, 31(31.0%) were high of triglycerides, 4 (4.0%) were low of triglycerides while 59 females were examined but 5(5.0%) have normal serum triglycerides, 46(46.0%) have high serum triglycerides and the remaining 6(6.0%) have low triglycerides. This clearly shows that most of the people sampled in this study have high level of serum triglycerides but male had normal triglyceride than female.

Vitiligo is a chronic autoimmune disorder characterized by patches of skin losing pigment due to the destruction of melanocytes, the cells responsible for producing pigment. The condition can affect people of all ages and ethnicities, with symptoms including milky-white patches on the skin, premature graying of hair, and color loss in mucous membranes like the mouth or nose. Among the main causes of vitiligo are; Autoimmune Response: Vitiligo is primarily an autoimmune disease where the immune system mistakenly attacks melanocytes, leading to depigmentation. Factors like family history, genetic predisposition, and immune system disorders contribute to its development, Triggers: Events such as sunburn, emotional distress, or exposure to certain chemicals can trigger or exacerbate vitiligo. The treatment options are; Medications: Treatments include light therapy (phototherapy), oral medications like psoralen combined with UVA light (PUVA), and depigmentation therapy using monobenzone to match skin tones Surgery: Surgical options are available for some cases of vitiligo and Psychological Support: Counseling and mental health services can help individuals cope with the emotional impact of vitiligo, in conclusion, v is a multifaceted skin condition lacking a conclusive remedy, many types of vitiligo, but the most common one is Non-segmental Vitiligo (NSV), honmental and genetic are the most important causes of vitiligo. Important symptoms of vitiligo are; depigmented patches, hair discoloration, sensitivity to sunlight, treatment of vitiligo have many approach, among them are; topical Corticosteroids, phototherapy and Cosmetic Camouflage.

Critical thinking is part of the skills needed in science learning in the 21st century. However, the PISA test results show that the level of critical thinking abilities of students in Indonesia is still relatively low. This research was carried out as an effort to overcome this, by developing teaching materials on reaction kinetics based on tetrahedral representations with an ethnoscience approach to improve students' critical thinking skills. This research was carried out in development stages involving 5 expert and practitioner validators and 66 students. Data was collected using questionnaires, observation sheets and test instruments. The data analysis technique used is descriptive data analysis technique, namely by describing the validity, practicality and effectiveness of the teaching materials being developed. The results of this research show that the teaching materials developed are very valid with a validity score of 90.91% and very practical with a practicality score of 90.97%. These results indicate that the teaching materials developed are suitable for use in order to improve students' critical thinking abilities.

Humans are a category that philosophers are always interested in research as they are the object and the subject of cognitive activity in social life. From a humanistic point of view, humans were mentioned in Renaissance philosophy as well as in the Enlightenment era as “Liberty – Equality - Fraternity”. Continuing that humanistic tradition, the ideal human perspective was analyzed more broadly and humanely by Ludwig Feuerbach based on the spirit on Enlightenment philosophy. Nevertheless, an humanistic view of humanity has not helped people liberate themselves to have a real life as Ludwig Feuerbach wanted. Humans – living and creative entities – want to liberate themselves and must participate in labor and struggle in practice life, which Karl Marx absorbed and developed in his research. Through Karl Marx’s theory of men, workers fight for a realistic happy life for themselves.

In the context of higher education, the development of academic literacy is crucial in enhancing students' ability to use academic language for critical thinking and information analysis. This ability serves as the foundation for effective academic writing skills. This study highlights the challenges faced by students in the Faculty of Education at Lambung Mangkurat University regarding academic literacy, including difficulties in explaining the background of the problem, formulating research objectives clearly, and developing coherent arguments. Furthermore, the importance of academic literacy practices in a social context is emphasized, where students need to identify valued communication practices within specific disciplines. The research findings indicate that learning activities are still focused on learning objectives that overlook academic literacy practices. Therefore, it is essential for educators to provide constructive feedback to students to help them develop an academic identity that aligns with teachers' expectations.

Introduction: Influenced by cultural, spiritual and religious beliefs. A lot of couples suspend sexual activities and resume at various different times due to influences by different factors. Materials and Method: This was a descriptive cross-sectional study among 376 postpartum women and nursing mothers visiting the immunization/infant welfare clinic, postnatal and family planning clinic at the University of Port Harcourt Teaching Hospital. Data were obtained using pretested semi-structured interviewer-administered questionnaire, which was designed based on variables from existing literature pretested and revised to ensure the quality of information collected. The data retrieved was analysed and variables presented in tables. Results: Approximately 2/3rd (66.0%) of the women had a tertiary level of education. The result show 200(53.19%) of the women started sexual activity less than 6 weeks after delivery, with about 43.6% of the participants reporting various sexual dysfunctions like loss of desire, dyspareunia, vaginal dryness and others. The majority of the women (89.9%) were knowledgeable about contraception and the majority of those who knew about contraception 222(59%), made use of it. A higher proportion of women who had puerperal complications used contraception. Logistic regression analysis showed that women on contraception were about 12 times more likely to resume sexual activity after 6 weeks. Conclusion: Early resumption of sexual intercourse is common to women irrespective of sociodemographics and obstetric characteristics.

Canola is an important crop with low levels of fatty acid and genetically produced from rapeseed. Canola oil is obtained by extract sources. Heavy metals are a unique form of toxin because they may exist in the environment for a longer period. Exogenous administration of gibberellic acid has been proven in several studies to increase crop output by affecting an important physiological process. This study of the aimed and objectives included the nickel sulphate stress in quantity 300 µM and gibberellic acid in quantity 0.25 mM in specific quantity and their effects on different plant functions. Super canola under stress condition when 0.25 mM GA3 was applied. Whereas, minimum reduction was observed in cv. Sherilla under stress condition when 0 mM GA3 was applied. Maximum Catalase was observed in cv. Results showed the Peroxidase (POD), catalase (CAT) and superoxide dismutase (SOD) are the most important protective enzyme systems in plants, and also the most important reactive oxygen species clearance system. Maximum Total Amino acid was observed in cv. Sherilla under control condition when 0 mM GA3 was applied. However, effect of GA3 application was observed non-significant and same for as varietal difference among two genotypes was observed non-significant. Overall, super canola performed better under stress or non-stress condition. Mustard plants exposed to nickel showed decreased morphological characteristics, which might be related to the degradation of plant architecture, which limits the capacity of water content and minerals absorption by plants, resulting in total development of plant loss.

Traditional teaching methods, such as two-dimensional PowerPoint presentations, are prevalent in anatomy education but must provide an in-depth perception of anatomical structures. This article discusses integrating 3D anatomy application in an Occupational Therapy course as an advanced technique for anatomical learning. The "Complete 3D Anatomy" app was employed to facilitate the teaching of anatomy structures. Students from 2 different cohorts, 93 from 2022 and 96 from 2023 test scores, were considered in this endeavor. The 2022 group used the 3-D app on their own time, compared to the 2023 group, who were required to use it in class for every lecture by the instructor. Results showed improvement in their test score from 71% (2022) to 87% (2023), with the integration of the 3-D as a class activity. Based on these results, it is concluded that the 3D anatomy app is an essential tool for comprehensive anatomical learning. For future courses, there is a plan to integrate further and assess the benefits of requiring students to employ a tablet or iPad equipped with 3D apps, along with a virtual dissection table to complement teaching and learning enterprises in the human cadaver laboratory.

This research analyzes the characteristics of Emirati Generation Z, millennials, and baby boomers, and the influence of social media to explain linguistic changes in the UAE. To do so, we administered a questionnaire containing 100 English words commonly used in Emirati Arabic; We have classified the types of English words and expressions used by the three generation cohorts. Participants also responded to a qualitative questionnaire, concerning the role that English played during the pandemic, Emiratis’ behavior towards social media, and their viewpoint regarding the influence of English in Emirati Arabic. Results showed that Generation Z uses more English words and expressions than the other two generations. Generation Z attended bilingual education in English and Arabic since primary school whereas most millennials and all baby boomers attended school exclusively in Arabic. We have examined that social media contributed to more English words in Emirati Arabic and determined the reasons why Generation G prefers to use English on social media and in their daily lives. We could conclude that Generation Z and most millennials see English positively and as inevitable progress in a globalized world while baby boomers see it as a threat to their language and culture. Generation Z also outperformed the other two generations regarding the pronunciation of words in English when speaking Emirati Arabic.

Premature loss is a serious problem that affects children oral health in Saudi Arabia. Different dental consequences could result after early loss of primary teeth if no proper treatment is applied. The aim of this review is to contextualise the previous studies about the parental knowledge and awareness towards the importance of primary teeth, causes and sequels of premature loss of these teeth and space maintenance appliances.

Lymphangiectasia is a secondary phenomenon that results from obstruction of previously normal lymphatic systems leading to dilation of the lymphatic vessels. Its occurrence in women is very rare. We report the clinical case of vulvar lymphangiectasia observed in a patient seen in gynecological consultation. The symptomatology was dominated by the appearance of vulvar swelling that had been evolving for 6 months and gradually increased in volume; the patient benefited from an exploration assessment which came back in favor of vulvar lymphangiectasia and was referred to a dermatological consultation for further treatment.

The narrative artistry on display in Agatha Christie’s Curtain: Poirot’s Last Case is both significant and outstanding. Central to this seminal work's success are its deft employment of a limited third-person narrative perspective, a narrative structure that seamlessly interleaves dialogue with clue collection, as well as several highly effective narrative techniques such as foreshadowing and misguiding. By utilizing a limited third-person perspective, Christie is able to adeptly provide the reader with enough information to remain engaged and invested, while simultaneously keeping a distance that allows for unexpected plot twists and revelations. In addition, the book’s unique narrative structure serves to further highlight the cleverness of Christie’s approach, with the novel flowing effortlessly from one clue-gathering scene to another, interspersed with revealing conversations between the characters and the ever-present Poirot. Finally, the use of narrative techniques such as foreshadowing and misguiding showcase Christie’s unparalleled skill as a writer of mystery and suspense. Through her employment of these techniques, Christie is able to further engage the reader, keeping them guessing and questioning their assumptions until the final revelation.

Data collected on certain physical parameters of Sri Kurmanadha, Srikurmam and Sri Maninageswar, Kallepalli, Temple Ponds, Srikakulam District, Andhra Pradesh from May 2014 to April 2016. The seasonal variations in water quality were recorded on monthly basis for a period of two years and correlation studies were also conducted among different physical parameters of both temple ponds. Water samples were analyzed for Physical Parameters like air temperature (28.250 C, 27.40 C), water temperature (240C, 24.350 C), transparency (32.1cm., 20.35cm.), EC (621μs/cm., 513.5μs/cm.), TSS (27mg/l., 35.5mg/l.) TDS (367mg/l., 298mg/l), pH (7.35, 7.5), DO (6.75mg/l, 6.5mg/l), COD (10.63mg/l, 10.36mg/l), BOD (3.31mg/l., 2.86mg/l.) total alkalinity (132.5mg/l., 128.5mg/l.), total hardness (80mg/l., 87.5mg/l.). Inter relationship between physical parameters (Pearson’s Correlation matrix) was also recorded. In this observation temperature showed strong positive correlation with COD (r=0.91, r=0.88), BOD (r=0.96, r=0.89), and negative correlation with DO (r=-0.84, r=-0.97). EC showed significant positive correlation with TDS (r=0.85, 0.89), and negative correlation with DO (r= -0.82, r=-0..84), TDS showed positive correlation with pH (r=0.77, r=0.72), and total hardness (r=0.81, 0.78), pH showed positive correlation with COD (r=0.77, r=0.84), total alkalinity (r=0.94, r=0.86), total hardness (r=0.81, r=0.84), and negative correlation with DO (r= -0.87, r=-0.77), Dissolved Oxygen showed negative correlation with COD (r= -0.88, r=-0.93), BOD (r= -0.95, r=-0.93). Chemical Oxygen Demand showed positive correlation with BOD (r= 0.92, r=0.91) and total alkalinity (r= 0.75, r=0.79). Biological Oxygen Demand showed positive correlation with total alkalinity (r= 0.74, r=0.63). Total Alkalinity showed positive correlation with total hardness (r= 0.90, r=0.87). These observations could useful in the water quality monitoring and regulation in order to enhance the quality of water with better sustainable management of Sri Kurmanadha, Srikurmam and Srimaninageswar, Kallepalli, Temple Ponds.