Correlation between Uric Acid and Lipid Profile in Untreated Dyslipidemic Patients
Talha Tariq, Mahnoor Fatima, Dr. Abid Ali, Hanana Maryam, Waqar Ahmad
Page Numbers : 338-344
DOI : 10.36348/sjpm.2022.v07i08.003
Background: The effects of cholesterol and statin therapy on serum uric acid (SUA) concentration are poorly known, and the latter's effects are even less clear. A mean atorvastatin dosage of 24 mg/dl satisfies the American Cardiovascular Assessment Campaign management objectives and dramatically lowers prevalence of chronic in individuals with cardiovascular events, according to the Greek Drug and Cardiovascular Evaluation research. We compare the temporal evolution of SUA levels in patients receiving standard treatment who received insufficient statin therapy (12 percent received statins) to patients receiving formalised care who received atorvastatin therapy almost exclusively (98 percent). Methods: In this study 160 individuals with abnormal lipid profiles in their blood were enrolled to investigate the connection between lipid profile and uric acid in dyslipidemic patients (dyslipidemia). It was a 5-month cross-sectional study conducted at Dr Abdul Sattar Lab Sialkot using a convenient sampling method. The uric acid, total cholesterol, triglycerides, LDL, and HDL cholesterol levels of enrolled participants were measured. In short, we performed uric acid and lipid profile tests on under-observation samples to investigate the association between uric acid and lipid profile parameters in the enrolled (dyslipidemic) individuals. Result: This research looks at people between the ages of 20 and 60. The Graph shows that (15) patients are between the ages of 20 and 30, (46) patients are between the ages of 31 and 40, (74) patients are between the ages of 41 and 50, and (25) patients are between the ages of 51 and 60.Patients of both sexes are covered. It was found that there exist significant positive relationship between uric acid and lipid profile in dyslipidemic patients. This study shows a positive correlation between LDL, triglycerides, total cholesterol and uric acid whereas a negative correlation was observed between HDL and uric acid. According to the current results, when uric acid rises, Total Cholesterol, Triglycerides, and Low Density Lipoproteins (LDL) rise as well. But High Density Lipoproteins (HDL) falls with the increase in uric acid levels. As a result, this study may be useful in reducing the incidence of related cardiovascular morbidities, and we will be able to predict dyslipidemia more accurately, which may further leads to CVDs. As the rate of CVDs rises in Pakistan, it is becoming increasingly necessary to investigate the factors that are directly linked to the disease. Conclusion: This article's objective was to investigate any connections between Uric Acid and Lipid Profile. Because dyslipidemia predicts the risk of coronary artery disease, so uric acid levels should be considered in these individuals for more complete risk factor prediction and treatment. Increased levels of lipid profile parameters can lead to serious heart diseases, and the only way to avoid this is to get a quick diagnosis of the disease.
Case Report
Aug. 3, 2022
Frontal Abscess Caused by a Rare Pathogen: Streptococcus constellatus
Brahim El Jebbouri, Brahim El Mostarchid, Miloudi Gazzaz
Page Numbers : 333-335
DOI : 10.36348/sjpm.2022.v07i08.001
Streptococcus constellatus is a microorganism that lives commensally in the oropharyngeal region, urogenital region, and intestinal tract. However, it can cause infection in patients with certain predisposing factors. We present a rare case of a right-sided frontal abscess caused by Streptococcus constellatus in a 47-year-old male with well-controlled type 2 diabetes mellitus patient who was injured by shrapnel pieces in the head and who was malnourished. The patient was successfully treated by surgical evacuation and antibiotherapy. Very few cases of brain abscesses caused by S. Constellatus have been reported in the literature. Only four cases in an immunocompetent patient have been reported to date.
Case Report
Aug. 3, 2022
Invasive Squamous-Cell Carcinoma of the Scalp
Brahim Eljebbouri, Mohamed Allaoui, Adil Belhachmi, Brahim El Mostarchid
Page Numbers : 336-337
DOI : 10.36348/sjpm.2022.v07i08.002
Squamous Cell Carcinoma (SCC) is an epithelial neoplasm arising from the malignant proliferation of keratinocytes and it is the second most common type of skin cancer behind basal cell carcinoma (BCC). SCC presents with a wide variety of clinical manifestations including erythematous patches and nodules although its most usual presentation includes indurated well demarcated ulcerative lesions. We present historical case of SCC of the scalp who made the extension and invasion the brain after eroding the vault.
Case Report
July 30, 2022
Hodgkin Lymphoma Revealed by Thoracic Epidural Spinal Cord Compression
Brahim El Jebbouri, Abad Asri Chrif, Miloudi Gazzaz
Page Numbers : 326-328
DOI : 10.36348/sjpm.2022.v07i07.013
Hodgkin Lymphoma is rarely diagnosed as spinal cord compression syndrome. Caused by an epidural mass, this complication is often encountered in a late stage of the disease. We report the case of a 52-year-old woman presenting with symptoms of low thoracic spinal cord compression due to an epidural tumor on the MRI. Emergent surgery was undertaken on this patient, consisting in laminectomy and tumor resection. After surgery, pain relief and mild neurological improvement were noticed. The histological study revealed a Hodgkin Lymphoma and the patient was referred to chemotherapy and radiotherapy. Though chemotherapy is the gold standard treatment for Hodgkin Lymphoma, surgical spinal decompression may be required in epidural involvement of the disease. Diagnosis may be suspected in the presence of lymphadenopathy and general health decay.
Original Research Article
July 30, 2022
Assessment of the Acute Toxicity of the Venom of the Kind of Tetraponera in the Rats
Ngoule Charles Christian, Embolo Elysée, Ngene Jean Pierre, Yinyang jacques, Manaoda Antoine, Adiogo Dieudonné
Page Numbers : 329-332
DOI : 10.36348/sjpm.2022.v07i07.014
The aim of this study was to determine the parameters of acute toxicity of venom of the kind Tetraponera, on the rats. It was an experimental prospective study carried out at the traditional phytotherapy center of treatment of “ASMASIDAP”, during 5 months, from 1st Feburary to June 30, 2015 and in the laboratory of the FMSP of the University of Douala. This center is situated in Ebang-Mekong, Bikok subdivisionin and Méfou and Akono division; the sampling consisted of a group of 42 rats distributed in 6 batches plus one witness. The lethal dose 50 obtained by the graphical method of Muller and Tainter gave us a value of 653.5 ± 0.12 mg / kg of body weight; The rats, after receiving the injections, hugged each other, squirmed, squealed, their heartbeats seemed to speed up. This study determined the LD50, which, according to scale of Hodge and Sterner, would be slightlytoxic. This study permits us to determine the acute toxicity of venom of kind of tetraponra. LD50 = 653.50mg/Kg of body weight.
Case Report
July 30, 2022
Olfactory Groove Anaplasic Meningioma: A Rare Histopathological Entity
Brahim El Jebbouri, Mohamed Allaoui, Mohamed Moutaoukel
Page Numbers : 321-325
DOI : 10.36348/sjpm.2022.v07i07.012
Intracranial meningiomas continue to challenge our best clinical efforts to eliminate them once discovered and deemed appropriate for treatment. Malignant meningiomas constitute 10% to 15% of all meningiomas and limited information exists regarding adjuvant treatment. The external whole brain irradiation is recommended. Traditional chemotherapy has proven ineffective; thus, new chemotherapeutic agents and new methods of delivery should be developed. Immunotherapy may be considered for patients with malignant meningiomas when all others previous treatment have failed. We report a case of anaplastic papillary meningioma. A 60-year-old woman presented with a 10-year history of gradually decreasing olfactory function. A magnetic resonance image demonstrated a large Olfactory groove meningioma. The tumor and the infiltrated dura were radically removed. Postoperatively, the patient remained neurologically intact. The treatment was complemented by external whole brain radiation.
Original Research Article
July 29, 2022
Assessment of Knowledge and Attitude about Sexually Transmitted Infections among Medical Students of Dhaka City, Bangladesh
Mahboob, N, Iqbal, H, Afrin, S, Abedin, F. Z, Ahmed, M
Page Numbers : 313-320
DOI : 10.36348/sjpm.2022.v07i07.011
Background: Sexually transmitted infections (STIs) are major public health problem in both developing and developed countries. Medical students should have adequate knowledge about STI as they will be dealing with patients in future. The objective of this study was to evaluate the knowledge and attitude about STIs among medical students. Materials and Methods: This descriptive cross-sectional study was conducted among the 184 medical third year students of private medical colleges of Dhaka. Data were collected using a structured questionnaire on sociodemographic information, knowledge of STIs and attitude towards it. The response format was based on a 3-point Likert scale. Frequency distribution was calculated for statistical analysis. Results: One hundred and eighty-four students participated in this study of which 76 (41%) were males and 108 (59%) were females. All of the respondents had ever heard about STIs. Internet was the most frequently source of information for STIs. Most of the students had fair knowledge about the sign and symptoms, transmission, complication and prevention methods of STIs but there were also students who didn’t knew and had misconceptions. Attitude of the students towards STIs was variable. Conclusion: This study indicates the gaps in the knowledge of medical students about STIs. Further research should be performed to investigate the reason behind this gap. Moreover, additional emphasis on the knowledge of STIs and prevention should be implemented into the curriculums.
