ORIGINAL RESEARCH ARTICLE | March 20, 2025
Preoperative Platelet-to-Lymphocyte Ratio and Serum Albumin as Predictors of Clinicopathological Outcomes in Cervical Cancer
Dr. Syfun Naher, Dr. Rita Roy, Dr. Nandita Sarker, Dr. Shamima Yesmin, Prof. Dr. Jannatul Ferdous, Dr. Naznin Akter Zahan, Dr. Fatema Nihar, Dr. Sunzia Sayed
Page no 115-120 |
DOI: https://doi.org/10.36348/sijog.2025.v08i03.007
Background: Cervical cancer remains one of the most prevalent cancers globally and a leading cause of cancer-related deaths among women. Early detection and precise prognostic assessment are vital for enhancing outcomes in cervical cancer patients. The purpose of this study is to evaluate the predictive value of preoperative PLR and serum albumin levels for clinicopathological outcomes in cervical cancer. Aim of the Study: The aim of the study was to evaluate the predictive value of preoperative Platelet-to-Lymphocyte Ratio and Serum Albumin levels on clinicopathological outcomes in patients with cervical cancer. Methods: This cross-sectional study, conducted at the Department of Gynecological Oncology, BSMMU, Dhaka (July 2022–June 2023), analyzed 120 women with early-stage (IA-IIA) cervical cancer to assess the association of PLR, S.Albumin for clinicopathological outcome using SPSS 27.0. Data included socio-demographics, clinical details, and serum markers. Results: The majority of participants were aged 30-44 years (46.7%) and married before 18 years of age (83.3%). Most had a PLR <128.3 (62.2%) and SA ≥3.5 (57.8%). Larger tumors (2-4 cm), higher prevalence of lymphovascular space invasion (LVSI), and deeper stromal invasion (≥½ thickness) were significantly associated with higher PLR (≥128.3) and lower SA (<3.5) (p < 0.001, p = 0.006). Conclusion: Preoperative Platelet-to-Lymphocyte Ratio and Serum Albumin levels can serve as valuable predictors of clinicopathological outcomes in cervical cancer, aiding in personalized treatment strategies.
Background: Preeclampsia and eclampsia, hypertensive disorders of pregnancy, are major contributors to maternal and neonatal morbidity and mortality in Bangladesh. Liver dysfunction, manifested as elevated liver enzymes, is a frequent complication in these conditions and can exacerbate adverse outcomes. Understanding the association between liver function abnormalities and maternal or neonatal complications is essential for improving clinical management. Objective: This study aimed to evaluate the alterations in liver function among Bangladeshi women with preeclampsia and eclampsia and their association with maternal and neonatal outcomes. Methods: This retrospective cohort study enrolled women diagnosed with hypertensive disorders of pregnancy who delivered in Institute of Applied Health Science (IAHS), Foy's, Lake, Chittagong, Bangladesh, from January 2024 to December 2024. A total of 60 eligible participants were selected based on predefined inclusion and exclusion criteria and were evenly divided into two groups: Group 1 comprised women with elevated liver function tests (above-threshold LFTs), while Group 2 included women with normal or below-threshold liver function tests (below-threshold LFTs). Maternal data were collected from medical records, including demographic information, obstetric history, and liver function test results. The cohort was stratified into two groups based on LFT results (above-threshold vs. below-threshold). Descriptive statistics and univariable analyses were used to identify differences between the groups, and multivariable logistic regression was employed to assess the association between elevated LFTs and adverse maternal and neonatal outcomes, adjusting for confounders such as maternal age, BMI, and gestational age at delivery. Statistical significance was set at p < 0.05. Results: Among mothers, blood transfusions were significantly more frequent in the elevated LFT group (16%) compared to the normal LFT group (5%, p = 0.011). Composite adverse maternal outcomes were higher in the elevated LFT group (20% vs. 15%, p = 0.38), though not statistically significant. Adverse neonatal outcomes were notably elevated, including NICU admission (68% vs. 52%, p = 0.041) and respiratory distress syndrome (41% vs. 25%, p = 0.029). The composite adverse neonatal outcome was significantly higher in the elevated LFT group (70% vs. 53%, p = 0.035). General anesthesia is associated with higher rates of adverse maternal and neonatal outcomes compared to regional anesthesia, with significant differences in maternal blood transfusion, neonatal ICU admissions, and respiratory distress syndrome. Regional anesthesia demonstrates a safer profile, particularly for reducing neonatal complications. Conclusion: Elevated LFTs in preeclampsia and eclampsia are associated with increased maternal and neonatal complications, including higher rates of blood transfusion, NICU admission, and respiratory distress syndrome. Routine liver function monitoring is critical for identifying high-risk patients and implementing timely interventions, especially in resource-limited settings.
ORIGINAL RESEARCH ARTICLE | March 20, 2025
Corrosion Behavior of Extracts of Yam, Maize and Cassava Leaves on Mild Steel in a Selected Media
Blessing J. Ifeanyichukwu, Ndubuisi E. Idenyi, Ozoekwem Raphael Obinna
Page no 68-77 |
DOI: https://doi.org/10.36348/sjet.2025.v10i03.004
Investigation of the inhibiting effects of Dioscorea rotundata, Zea mays and Manihot exculenta leaves extracts on the corrosion of mild steel in a selected media using weight loss method was carried out. The mild steel samples were pre-weighed, immersed in mixture of NaOH, NaCl and H2SO4 solutions with the extracts from the leaves and the control samples immersed in solution of the media with no extracts. The samples were allowed to stand for 672 hours and a set of samples from each environment withdrawn at intervals of 168 hours for corrosion characterization. The research findings indicate that the corrosion rate decreased as a result of the leaves extracts introduced into the media thereby confirming that the extracts functioned as effective and excellent inhibitors in the alkaline, salt and acidic media. Among the three plants extracts used, it was observed that Dioscorea rotundata (Yam) has the best inhibition efficiency in both alkaline, salt and acidic media, followed by Manihot exculenta (Cassava) and Zea mays (Maize) which also showed good inhibition efficiency. The results show the very good potentialities of the leaves extracts for application in the mitigation of corrosion in our various manufacturing industries.
CASE REPORT | March 20, 2025
Anesthetic Outcome of a Primigravida Woman with Acute Fatty Liver of Pregnancy (AFLP) Complicated by Multiorgan Dysfunction Syndrome (MODS): An Obstetric Emergency
Dr. Sheikh Rukun Uddin Ahmed
Page no 123-127 |
DOI: https://doi.org/10.36348/sjm.2025.v10i03.009
Acute fatty liver of pregnancy (AFLP) is a rare but life-threatening obstetric emergency, often complicated by multiorgan dysfunction syndrome (MODS). We report a case of a 25-year-old primigravida woman at 34 weeks and 7 days of a twin pregnancy presenting with abdominal pain, nausea, and vomiting for three days. Diagnosis was established based on clinical, laboratory, and imaging findings. Prompt multidisciplinary management, including termination of pregnancy and intensive care support, resulted in a favorable maternal outcome. This case underscores the importance of early recognition and aggressive intervention in AFLP complicated by MODS.
يعتبر شعر المناسبات من الفنون الأدبية الأكثر انتشار لدى الشعراء في دولة صكتو في القرن العشرين وكانوا يقرضون أشعارا في مناسبات وذكريات كثيرة لها أهيمة لديهم, ومن جملة هؤلاء الشعراء الشاعر أحمد صابر, وقد أدلى دلوه في هذا الفن حيث قرض أشعارا كثيرة في هذا المجال في أسلوب رائع مشتمل على الصور الفنية والظواهر البلاغية تشهد على تمكنه في قرض الشعر, والتعبير عما في ضميره وشعوره بكل فصاحة وبلاغة, يهدف هذا البحث إلى الوقوف على نونية الشاعر في ذكرى وفاة والده الحاج محمد نَتَعَالَى, لإخراج ما تضمنته من صور بلاغية وتحليلها حسب توظيف الشاعر لها, ثم الإشارة إلى أهم ما وصل إليه البحث من نتائج. ويشتمل البحث على الكلمات الافتتاحية التالية: الشاعر أحمد صابر, عرض القصيدة, صور بلاغية في القصيدة ,الخاتمة ونتائج البحث..
ORIGINAL RESEARCH ARTICLE | March 19, 2025
Levels of Interleukin-39, C–Reactive Protein in Patient's Serum with H. Pylori Infections
Khalil Ismail Abid Mohammed, Ameen Abdul Hasan AL-Alwany, Sarmad M. Zeiny, Saad Hasan Mohammed Ali, Wifaq M. Ali, Suha A. AL-Fakhar, Jinan M. Mousa
Page no 119-122 |
DOI: https://doi.org/10.36348/sjm.2025.v10i03.008
The study was carried out to detection of H.pylori in (200) patients who attended two teaching hospitals in Baghdad. The diagnosis done by Immunochromatography methods. Stools and blood samples was taken from each patient as well as other (30) healthy control matching in their age. The study included detection the Levels of Interleukin-39 and CRP in sera of patients and control. The result indicated presence of H pylori antigen in 115 cases 59 cases of males and 51 of females, Also, the result indicated increasing levels of IL-39 and CRP in patients sera in comparison with healthy control.
Bone fracture is considered to be one of the common problems faced by the majority of population all over the globe. In this context the only option available with the person affected is the either the plaster or the surgery followed by the plaster. Along with this the anti-inflammatory medications as well as calcium containing drugs are being recommended for the early recovery of the patients. The problem with the medication and plaster is that the person feels a lot of discomfort. Itching, skin irritation, poor blood circulation due to tight plaster, pressure sores, infection with wetting of plaster and displacement of bones with losing of plaster might take place. Even the drugs recommended in this case like analgesic and anti-inflammatory medications might results in potential side effects. In this regard it is better to find some alternate for the same. In the recent, herbal plants are being recommended for the treatment of bone fracture. The different formulations can be designed for the delivery of the herbal constituents as the medication for fracture. In the present paper the detail description of herbal plants are being highlighted which have shown the potential of healing fracture.