Cryptococcemia in a COVID-19 Patient: A Case Report
Loubna Darfaoui , Mohamed Esbaai , Ayoub Belhaj, El Aissaoui Youness, El Mostafa El Mezouari, Redouane Moutaj
Page Numbers : 82-83
DOI : 10.36348/sjm.2022.v07i01.013
Cryptococcosis is a frequent and severe opportunistic mycosis caused by encapsulated yeast of the genus Cryptococcus. It is common in immunocompromised patients, particularly those infected with the human immunodeficiency virus. We report in our work a case of cryptococcemia in a patient with covid-19 under anti-inflammatory treatment. The diagnosis was based on the presence of encapsulated yeasts with Indian ink and positive culture on Sabouraud medium without cycloheximide with identification of Cryptococcus neoformans as the causative agent. The patient's outcome was fatal.
Original Research Article
Jan. 28, 2022
Seroprevalence of HBV Infection in a Tertiary Care Hospital in Bangladesh
Dr. Suzauddin Talukder, Dr. Mohammad Motiur Rahman, Dr. Issa Muhammad Baker, Dr. Anupam Das, Dr. Farjana Najnin, Dr. Shamima Nasrin
Page Numbers : 71-81
DOI : 10.36348/sjm.2022.v07i01.012
An estimated 1 million people die each year from HBV infection. This investigation aimed to determine the frequency, distribution, and risk factors for HBV infection in a healthy Bangladeshi community. A cross-sectional study among the general population was conducted in Dhaka Medical College Hospital. A series of 100 patients with the chronic liver disease between 18 to 49 years. Diagnosed based on clinical and biochemical parameters were collected. All medicine units of Dhaka Medical College Hospital have been analyzed regarding the seroprevalence of HBsAg and its correlation with the demographic pattern. Among 100 cases of liver disease, the number of CLD patients was 85, of which 56 (65.88%) were HBsAg positive 29 (34.11%) were HBsAg negative. The number of patients with acute viral hepatitis was 15, of which 4(26.66%) were HBsAg positive, 11(73.33%) were HBsAg negative, and the overall seroprevalence was 60%. The age incidence was more below 40 years (83%) less above the age of 40(17%). Males had higher seropositivity (70.31%) than females (41.66%). People of all ages are susceptible, particularly the farmers (21.66%) and manual laborers (13.33%). Most of the patients belong to the poor (62.79%) and middle class (62.22%). Urban people were more (60.93%) susceptible than rural people (58.33%). Married persons were more (70.27%) prone than unmarried (30.76%). Seroprevalence of HBsAg was more in those people who had a history of blood and blood product transfusion (84.61%). Illiterate persons were more (75%) susceptible than literate (59.37%). Seroprevalence of HBsAg was more in those who had a history of instrumental tooth extraction (68.42%) than those who had not (58.02%). People who cut their beards and mustache in the barbershop were more susceptible (73.91%) than those who got it by themselves (68.29%). Among female persons, those who underwent instrumental delivery were more susceptible than those who delivered their baby by normal vaginal delivery.
Original Research Article
Jan. 24, 2022
In-Hospital Outcome and Angiographic Profile of Elderly Patients with Non-ST Segment Elevation Myocardial Infraction
Masum MS, Malik F, Mahmud MS, Zaman M
Page Numbers : 62-70
DOI : 10.36348/sjm.2022.v07i01.011
Background: Non-ST Segment elevation myocardial infarction is heterogeneous in its presentation. Like ST-segment elevation myocardial infarction, non-ST-segment elevation myocardial infarction is life-threatening of a major cause of emergency medical care and hospitalization. Patients with non-ST segment elevation myocardial infarction are at risk for adverse cardiac events, so the initial treatment is very important. Increasing age is a strong predictor of adverse events in non-ST segment elevation myocardial infarction patients. Objective: To determine the in-hospital outcome and severity of coronary artery disease of older patients with Non-ST Segment elevation myocardial infarction. Methods: This was a descriptive cross-sectional study. The study was carried out in the cardiology department, National Heart Foundation Hospital, and Research Institute from June 2011 to May 2012. Patients of Non-ST Segment elevation myocardial infarction admitted at National Heart Foundation & Research Institute who fulfill the inclusion criteria were the study population. Patients were recruited by nonrandom sampling. One hundred and thirty-four patients were recruited in this study. Data were prospectively collected in a pre-designed data collection form and analyzed using SPSS - 16 software. Results: In this study, patients had a greater prevalence of hypertension diabetes mellitus. Chest pain and shortness of breath were common presentations observed in study patients during admission. They had a lower left ventricular ejection fraction than their younger counterparts. The older group was associated with an increased risk of triple vessel disease. In-hospital complications were significantly higher in older patients. Duration of hospital stay was longer in older patients. Conclusion: Older patients with Non-ST Segment myocardial infarction strongly predict adverse in-hospital outcomes and severe coronary artery disease profiles. Older patients should alert physicians to an increased risk of morbidity and mortality, which may, in turn, support more judicious treatment, including appropriate utilization of cardiovascular diagnostic tests and therapeutics used in current cardiovascular care to optimize outcomes in these high- risk patients.
Original Research Article
Jan. 19, 2022
Superficial Mycosis at the Avicenne Military Hospital in Marrakesh: 5-Years Review
Raja Nakhli, Mohamed Sbai, Salma Rouhi, Redouane Moutaj, El Mostafa El Mezouari
Page Numbers : 52-56
DOI : 10.36348/sjm.2022.v07i01.009
Superficial mycosis were diagnosed in 1231 cases, a prevalence of 62.07%. The average age of the patients was 45 years, the sex ratio M/F was 1.19. The majority of the patients were followed as outpatients (96.99%). Of all superficial mycosis, onychomycosis was the most frequent with a rate of 52.32%, followed by epidermomycosis (37.44%), scalp mycosis (8.37%), oral mycosis (1.71%) and genital mycosis (0.16%). Dermatophytes were the most isolated (85.05%), followed by yeasts (13.65%), molds (1.30%). The main dermatophytic species were represented by Trichophyton rubrum (80.99%), followed by Trichophyton mentagrophytes var. interdigitale (8.88%) and Microsporum canis (6.59%). The most common yeasts found were Candida albicans (67.86%), followed by Malassezia furfur (22.02%). Scopulariopsis brevicaulis was the most isolated mold (68.75%). At the end of this study we conclude that mycological examination is essential in the management of patients with superficial mycoses; which must also include the elimination of favourable factors in order to avoid recurrence.
Original Research Article
Jan. 19, 2022
Obesity, A Preventable Burden of Disease among Children
Dr. Asma Abdul Qadeer, Dr. Rabia Mehmood, Dr. Nadia Junaid, Dr. Sara Bashir, Dr. Saadia Baran, Dr. Saira Mahmood
Page Numbers : 57-61
DOI : 10.36348/sjm.2022.v07i01.010
Background: In last few decades, childhood obesity has become a burdensome challenge globally. The most important long-term consequence of childhood obesity is its persistence into adulthood, with all the associated health risks. Persistent obesity is established before the age of 11. Methods: A descriptive cross sectional study with non-probability convenient sampling was carried out over a period of three month in a private sector school Islamabad, Pakistan. The sampling frame was 250 students of grade 4 of roots school system. The response rate was 67%. Results: Mean age in our sample was 10 years. Mean BMI was 18.14 with a standard deviation of 4.4. The frequency of obesity in children was 22% (more than 97th percentile and equivalent to BMI of 30kg/m 2) and that of overweight was 32% (more than 85th percentile and BMI of). Among obese children 28% were reasonably physically active the past week. Regarding eating habits 52% children ate their breakfast every day, 16% of the children never had their breakfast because they didn’t like breakfast or because they were never given breakfast at home. 55% of the children thought that obesity can be prevented by making sure that children are into sports and games, by promoting healthy snacks and banning fast foods, by launching fitness programs and by health education. Conclusion: We found a high frequency of obese and overweight children in the private sector school of Islamabad. Physical inactivity and relationship with other factors like watching TV, gaming and over consumption of junk food was found to be associated with overweight and obesity adds some useful data to the previous researches.
Review Article
Jan. 17, 2022
Among The Largest Population Which Age Group is the Most Having Polycystic Ovarian Syndrome
Muhammad Bilal, Syeda Khadija, Nosheen Arshad, Sana Saleem
Page Numbers : 42-44
DOI : 10.36348/sjm.2022.v07i01.007
Background: Polycystic Ovarian Syndrome (PCO), also called Hyper androgenic anovulation (HA), or Stein-Leventhal syndrome is a very common disorder of ovaries that only occurs in females mainly of reproductive age of 4% to 20% approximately. It is a condition in which multiple cysts, almost 9 to 10 are noted in the ovary, can be on one side or both sides and the volume of the ovary exceeds 10ml. The common representation of PCOS includes obesity, acne, hirsutism, and complications in pregnancy. Objective: To evaluate among the largest population which age group is the most having polycystic ovarian syndrome. Methodology: A literature search was performed with the use of search engines. The search engines that provided the articles for systemic review are Google Scholar, MDPI, PubMed, Medscape, and NCBI. For article searching following keywords were used: Polycystic ovaries, reproductive age changes, and age group. Conclusion: It is concluded that there is a specific age that has Polycystic syndrome ranging from 12-25.
Original Research Article
Jan. 17, 2022
Attenuation of Fear and Anxiety Related Behaviours by Ethanolic Leaf Extract of Gongronema latifolium in Swiss Albino Mice
Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. To cope with anxiety, people employ potentially harmful strategies like alcohol, cigarettes, medication, withdrawal etc. which may cause panic disorder to worsen. Gongronema latifolium (GL) is one of the medicinal plants used in the treatment of ailment including mental disorders. This study was therefore aimed to elucidate effects of administration of ethanolic leaves extract of fear and anxiety using light/dark transition box. Thirty (30) adult male Swiss white mice were assigned into three groups of ten mice each, thus: control, low and high dose groups placed on 0.9% normal saline, 200 mg/kg and 400 mg/kg of ethanolic leaves extract of GL respectively. All the animals were allowed food and water ad libitum. Results showed significant (p<0.001) increase in the frequency of line crosses, rearing activities in the extract treated groups when compared to the control. There was a corresponding decrease (p<0.001) stretch attend posture, freezing, grooming frequency and grooming duration in the test groups when compared to the control. These indices show that the extract treated groups of mice exhibited decreased fear and anxiety behaviours when compared to the control group. In conclusion, extract of Gongronema latifolium could be used as an anxiolytic for anxiety related disorders due to its ability to attenuate fear and anxiety related behaviours in mice.
