Worldwide, the prevalence of overweight and obesity due to lifestyle is on the rise. Numerous health problems, including metabolic disorders, diabetes mellitus, and cardiovascular diseases, are significantly correlated with it. This study evaluated the protective effects of selected varieties of Solanum lycopersicum on liver and kidney markers in albino rats fed with a high-fat diet (HFD). A total of twenty-five healthy male albino rats weighing between (150–180 g) were fed high fat diet for the first four (4) weeks, and rats weighing above 300g were randomly divided into five groups of five rats each for another four (4) weeks. Group 1 served as the normal control group, Group 2 served as the negative control (rats fed a high-fat diet only), Group 3 was administered the standard drug (5mg/kg Lovastatin), Groups 4 and 5 animals were administered 200mg/kg body weight of two different varieties of Solanum lycopersicum. After 4 weeks of administration, rats were euthanized, blood sample was collected and centrifuged for analysis. The serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), Total bilirubin (TB), Conjugated bilirubin (CB), total protein (TP), albumin, (ALB) creatinine, urea, uric acid, and electrolytes were measured. The results showed a significant (p < 0.05) elevation of liver enzymes and kidney markers in HFD-fed rats. At the same time, the Solanum lycopersicum-treated groups exhibited a marked improvement in both liver and kidney parameters compared to the HFD control. The study concludes that Solanum lycopersicum possesses hepatoprotective and renoprotective potential, suggesting its nutritional importance in preventing diet-induced metabolic disorders.

China has high-speed development in the long term, while environmental protection is also given importance by society. The evidence of China can be analyzed and emulated by other countries. The project of ESG is popular globally, and the carbon intensity is considered an essential factor for the country, and economic growth may decrease the carbon intensity because economic growth is fueled by industry transition. The primary and secondary industries are not as efficient as the tertiary industry. This essay can give evidence to policymakers or independent units to make decisions under sustainable development. This study uses Stata software to conduct the analysis, and the analysis employs Chinese economic data and carbon-related data from world bank and the OWID CO₂ Dataset, respectively, from 1965 to 2024. The model chooses Carbon Intensity as the dependent variable and chooses Economic Growth as the independent variable. After that, the model employs Coal CO₂ Emissions per Capita, Services, Value Added (% of GDP), and Oil CO₂ Emissions as the Control Variables. From the empirical analysis, we can draw the conclusion that Economic Growth and Services, Value Added (% of GDP) are significantly associated with carbon intensity. And Coal CO₂ Emissions per Capita and Oil CO₂ Emissions are positively significantly associated with carbon intensity. China is an acute evidence for the developing countries to conduct an industry transition, and the carbon intensity decrease associated with a high-quality environment, which benefits all the citizens living in the country. The air conditioning and temperature also affect the earth ecosystem indirectly. China is still investing human, political, and capital resource to the tertiary industry and is accelerating the industry transition, which boosts its economic growth. Environmental protection should be put in the right place and be associated with the quality of living standards.

This study examines Libyan computer science students’ perspectives on their English for Specific Purposes (ESP) textbook and explores the challenges associated with their use of this textbook in the tertiary education context. A questionnaire adapted from established ESP evaluation frameworks was administered to a sample of 53 undergraduate computer science students. The findings reveal a significant discrepancy between the textbook’s organizational structure and its pedagogical effectiveness. While students acknowledge the clarity of the textbook’s layout and sequencing, they report substantial shortcomings in its instructional content. Specifically, the material is perceived as outdated, overly theoretical, and a lack of authentic, discipline-relevant tasks. Moreover, the results indicate a significant imbalance in skills coverage, with a predominant focus on reading while neglecting listening, speaking, and writing skills that are essential for academic and workplace communication in computer science. The study concludes that the textbook, in its current form, does not adequately align with core ESP principles and therefore requires substantial revision and supplementation with contemporary, practice-oriented materials to better equip students with the communicative competencies demanded by their field.

Background- Pyogenic granuloma is a common reactive oral lesion characterized by rapid vascular proliferation and tissue remodeling. Matrix metalloproteinase-2 (MMP-2) and its regulators, TIMP-2 and RECK, are key modulators of extracellular matrix turnover and angiogenesis, but their roles in pyogenic granuloma remain unclear. Aim- This study aimed to assess the expression and possible role of MMP-2, TIMP-2 and RECK in the biologic behaviour of Pyogenic granuloma. Methods- This was a laboratory based immunohistochemical study of pyogenic granuloma cases seen at the Department of Oral Pathology/Oral Medicine, UCH Ibadan, Nigeria between January 2000 and December 2011. 50 cases of pyogenic granuloma were sectioned and stained with commercial antibodies for MMP-2, TIMP-2 and RECK. Immunohistochemical staining of cells in individual cases was assessed at X100 magnification. Immunohistochemical assessment of MMP2, TIMP2 and RECK were expressed in proportions/percentages. Mean scores for MMP-2, TIMP-2 and RECK as well as MMP-2: TIMP-2 and MMP-2: RECK in all the cases of pyogenic granuloma were compared using the Independent Sample T test. Results- All of the cases expressed MMP2 and 88% of cases expressed TIMP-2 while RECK is positive in 80%. The mean MMP2: RECK ratio in pyogenic granuloma is 2:1. TIMP -2 is significantly higher in males than females (p = 0.005) while mean MMP2:TIMP2 is significantly higher in females than males (p = 0.000). Pearson correlation and regression analyses were performed to explore the relationships between MMP-2 and its inhibitors, TIMP-2 and RECK, in pyogenic granuloma. A weak negative correlation was observed between MMP-2 and TIMP-2 expression (r = −0.093), which was not statistically significant (p = 0.521). Similarly, simple linear regression analysis showed that MMP-2 expression was not a significant predictor of RECK expression (β = 0.02, p = 0.882), with the model explaining virtually none of the variance (R² = 0.00). Conclusion- MMP-2 is expressed in all pyogenic granuloma cases and exceeds the levels of its inhibitors, TIMP-2 and RECK, consistent with its role in driving angiogenesis. Its expression appears largely independent of TIMP-2 and RECK, suggesting additional regulatory factors influence MMP-2 activity in these lesions.

Background: Hypertensive crisis is a continuum of elevated blood pressure that may cause acute target-organ damage and represents life-threatening complications if not treated and controlled urgently. Although the emergency department (ED) setting has historically been advocated as the appropriate environment for acute blood pressure control, the importance of enhanced primary care in responding to some high-risk vascular presentations is increasingly emphasized in modern healthcare systems. Comparative “Real-world” data on outcomes in the management of HC by ED and primary care (PC) perspectives regarding treatment of patients presenting with HC in the Middle Eastern health system is scarce. Objective: To compare clinical management, time to blood pressure control, complication rates and outcome of hypertensive crisis between emergency department (ED) and primary care setting in Qatar. Methods: A parallel observational study was done in 75 adult patients diagnosed with hypertensive crisis from January to November 2025. Patients were treated in ED (n = 45) or primary health care (n = 30). Demographics, comorbidities, treatment approaches, time to response and outcomes were described and compared by statistical methods using test of significance (p < 0.05). Results: In ED patients who were managed with IV antihypertensive treatment, blood pressure reduction was significantly faster, intravenous antihypertensive use was significantly greater, and early complication rates were significantly lower. The majority of cases of hypertensive urgency were effectively controlled with oral pharmacracy and outpatient follow-up at primary care centers. Blood pressure was controlled in total in 66.7%, partially in 25.3% and was uncontrolled with continued medication in 8.0%. Conclusion: Emergency departments are essential for hypertensive emergencies, but appropriately resourced primary care facilities can safely and effectively treat hypertensive urgency, preserving healthcare resources and mitigating inappropriate hospital use.

The fingerprint examination is one of the most reliable methods of personal identification in forensic science due to the uniqueness and permanence of friction ridge patterns. In addition to primary ridge characteristics and minutiae, microscopic features such as sweat pores (level 3 fingerprint details) provide valuable information for detailed Forensic analysis. The present study was conducted to evaluate the potential of sweat pores characteristics in determining the age and sex of individuals through Poroscopic examination of fingerprints. A total of 150 participants were included in the study and categorized into three different age groups, each consisting of 25 males and 25 females. The fingerprint samples collected from all participants were examined under a digital microscope at 50x magnification, and specific pore parameters such as pore size, pore shape, interspacing between pores, and pore density were analysed. The combined analysis of these pore parameters indicates that poroscopy can provide useful microscopic information that may assist forensic examiners in estimating the approximate age group and differentiating between individuals based on sweat pore characteristics.

Movement is one of the major characteristics of every living thing. Transportation involves the movement of people, goods and services from one place to another and with increased population congestion is inevitable. Eastern mass junction Nkwo Triangle Nnewi North (Cross intersection) is not exempted from traffic congestion as it was taken as a case study for this work which focused on the analyses of traffic characteristics and design of traffic signaling control for management of busy intersections. Eastern mass junction Nkwo triangle Nnewi is connected by four roads leading Eastwards to the junction is Eke Amobi road, Westwards is First bank road, Northwards by Nnobi road and Southwards by Round-About junction road. The geometry of the junction is symmetrical towards North and South (8.1 meters) and asymmetric towards East (13.425 meters) and West (12 meters). Based on traffic volumes converted to the PCU values, a traffic signaling scheme was designed mostly based on the Webster’s method of signaling design using the geometries of the roads leading to this junction. Results from signal design showed an optimum cycle lengths of 73 seconds with total effective green times of 55 seconds and amber time of 5 seconds. The designed traffic signal is recommended for Eastern mass junction and other similar junctions to improve their traffic characteristics and reduce the demerits of congestion and delays.