Sphingomonas are ubiquitous bacteria, widely distributed in the nature, soil and water including the water sources in the hospital environment, contains at least more than 30 species, which of only paucimobilis is an occasional pathogen.1 It is one of the non-fermenting Gram-negative bacilli that is emerging as an opportunistic pathogen . S.paucimobilis is considered to be the organism of low virulence likely owing to absence of endotoxin and typical polysaccharide and thus responsible for less mortality and morbidity but sometimes can lead to septic shock. To support this, retrospective study conducted at our hospital on total 1580 inpatient (IP) blood samples for culture yielding positivity of 0.44% for the growth of S.paucimobilis, did favour the survival of the all the patients. All the blood isolates produced distinct white or off-white coloured colonies on blood and chocolate agar hence referred as “Bleached Sphingomonas paucimobilis.”
REVIEW ARTICLE | Nov. 9, 2020
Spinal Tumors- A Case Series of 5 Cases with Clinicopathological Review
Nitika kumari, Sai Sudha, Mary Lily
Page no 453-458
Background: Spinal tumors are tumors that can occur within or adjacent to the spinal cord. It can be primary tumors or secondary/ metastatic tumors. Primary tumors of the spine are rare and most of these lesions are asymptomatic. Primary spinal cord tumors account for 2 to 4 percent of all primary central nervous system (CNS) tumors. Spinal tumors are classified based on their location as extradural and intradural. Intradural tumors can be intramedullary spinal cord tumors (IMSCT) or intradural extramedullary (IDEM). Objective: To review the clinicopathological features of 5 histologically confirmed spinal tumor cases. Material & Methods: This study includes 5 cases of spinal tumors diagnosed by histopathological examinations. Result: Out of 5 cases we got 2 meningiomas, 1 spinal angiolipoma,1 schwannoma, and 1 myxopapillary ependymoma. Conclusion: The study can contribute to epidemiologic knowledge of Spinal cord tumors
ORIGINAL RESEARCH ARTICLE | Nov. 16, 2020
A Prospective Study on Medullary Carcinoma of Thyroid with Possible Clinical, Cytological and Histopathological Correlation
Dr. Bodepudi Madhavi
Page no 459-465
It is a prospective study done between 2010 to till date on 1123 thyroid lesions to estimate the incidence of medullary carcinoma of thyroid. Fine-needle aspiration (FNAC) was the initial diagnostic procedure to evaluate thyroid lesions. This study correlates FNAC cytology results with clinical, radiological and histopathological findings. Repeat FNAC and Ultrasound guided FNAC was done for inadequate samples and for difficult to palpate lesions. Medullary thyroid carcinoma is a hormone-producing malignant tumor that synthesizes calcitonin. MTC can be Sporadic or Familial. MTC is suspected after physical examination by measuring plasma calcitonin. For a positive diagnosis, histopathological confirmation is required. The extent of the tumor and the presence of metastatic spread are determined by using ultrasonography (USG), Computed tomography (CT) and Magnetic resonance imaging (MRI). A ims and objectives: To study the Incidence, cytological, histopathological and clinical correlation of medullary carcinoma of thyroid and to confirm the previous findings mentioned in the literature and to find any other additional findings from the histological and cytological view. To show the unique nature, rarity, and associations of medullary carcinoma. Marterials and methods: This study was conducted in the department of pathology in Mamata Academy of medical sciences Hyderabad and Mamata medical college. The material comprises of FNACs and thyroid specimens from Mamata General Hospital, Khammam and Mamata Academy of medical sciences from January 2010 to January 2020. Data was obtained from the surgical and pathology departments of Mamata General Hospital Khammam and Mamata Academy of Medical Sciences, Hyderabad Telangana. Routine Hematoxylin and Eosin, Pap stains were used to stain the smears and slides. For confirmation Congo red and calcitonin special stains were used and by checking baseline Calcitonin levels.
REVIEW ARTICLE | Nov. 16, 2020
Antimicrobial Activities of Selected Medicinal Plant with Potential Role of Chemical Compounds
Aysha Iftikhar, Adnan Shahid, Syed Saifullah Shah, Sajid Ali, Mohsin Raza, Ebadet Ali, Shaheena Umbreen
Page no 466-470
Several studies about the medicinal plants provide the evidences about the chemical compounds found in onions. These compounds included the catechole as well as ferulic acids, quercetin and kaempferol. The efficiency of the kaempferol has maximum as compared to the quercetin to inhibit the growth of the B.cereus. The antimicrobial activity of the plants has been precisely studied in the experimental investigations. The ultimate goal of all chemicals obtaining from the plants to target the major groups of the bacteria that causes diseases in human body, fishes and also other animals. There are certain gaps in literature about the different activities of the extracts of the onion. The antimicrobial activity of the onion extract remains unclear because of different microbes such as E.coli and S.aureus showing the resistance against the particular compound. Several relevant data and other research based studies showed comprehensive relationship to the antimicrobial activity of the onions in vitro against the different types of the microbes that causes different diseases such as Escherichia coli, Salmonella shigella, Vibrio cholera and Staphylococcus aureus. Quercetin and its related compounds possess the sulphur as a functional group. So, onions broadly used to treat the medical related disease in such a way that less side effected products obtaining from the plant in comparison to the industry that completely synthesized the products chemically and hence has more side effects.