Benign prostatic hyperplasia (BPH) is a non-malignant proliferation of prostatic cells resulting in glandular and stromal enlargement. It afflicts men in their advancing years resulting in lower urinary tract symptoms and alteration of quality of life (Qol). Diabetic patients seem to have larger prostate volumes than non-diabetic counterparts and this has formed an area of intense research interest. The aim of this work was to answer the research question: whether there is any significant difference in prostate volume between diabetic and non-diabetic men diagnosed with BPH. Materials and Methods: We retrospectively studied one hundred and thirty two (132) patients over a period of one year between October 2022 and September 2023 who presented in our Urology clinic for evaluation. Information were retrieved from their case notes and entered into a proforma. Data generated were analysed and used for this study. Results: Out of the 132 patients, diabetic men were 36(27.3%) while non-diabetics were 96 (72.7%). Mean overall age was 62.61±8.83 years, mean prostate volume was 59.53±45.50m/s and there was a significant mean difference in prostate volume between diabetic and non-diabetic populations (P=0.027). Conclusion: The research concluded that prostate volume in diabetic patients was higher than prostate volume in non-diabetic BPH patients.