ORIGINAL RESEARCH ARTICLE | Dec. 12, 2022
The Effect of Viruses on Blood Transfusion, an Applied Study on the Hafr Al-Batin Blood Bank
Hadia Farhan Al-Dahmeshi Al-Enizi, Aref Awad Al-Shammari, Mohammed Shabout Al-Shammari, Eidah Adehim Ageel Al-Dhafiry
Page no 446-456 |
10.36348/sjpm.2022.v07i12.001
The fact that blood groups can act as receptors/coreceptors for bacteria, viruses, and parasites demonstrates the importance of blood groups in infection. Blood group antigens also aid in cell adsorption, signal transmission, and/or membrane micro-domain retention. Furthermore, blood type can influence the innate immune response to infection. This data was compiled using the risk perception of blood transfusion scale, which is part of a larger risk perception questionnaire. Blood transfusion risk perception is measured on a 7-point Likert scale based on a set of qualitative characteristics; 119 participants in Hafr Al-Batin blood bank had a significant difference in risk perception of blood transfusion due to receiving blood, whereas those who had never received blood had no risk perception. as much risk perception of blood transfusion, and because of viral hepatitis infection, those who did not have viral hepatitis had more risk perception of blood transfusion, but there is no significant difference in risk perception of blood transfusion due to gender, age, educational level, and blood donation. The implementation of strict donor pre-screening and preventative measures to control infections in the general population, as well as the introduction of new, more sensitive screening tests, could significantly reduce transfusion-transmitted viral infections across eastern Saudi Arabia.
REVIEW ARTICLE | Dec. 15, 2022
Role of Interventional Radiology in Management of Hepato-Cellular Carcinoma (HCC)
Mubarak Naji Bin Mubarak Al Yami, Mahdi Ali Bin Mohammed Al Sharyah, Ahmad Saleh Al Qahhat, Mahdi Naji Bin Mubarak Al Yami, Ali Saleh Bin Ali Almassad, Saeedah Hamad Hassan Alshaiban, Mohammed Dhafer Abdullah Alghubari, Amal Abdullah Yahya Al Shahrani, Muhammad Husain Al Mutlaq, Fahad Saleh Mohd Albakry, Fatima Mohammad Saad Al Shahranii
Page no 457-462 |
10.36348/sjpm.2022.v07i12.002
The most typical primary liver tumour, hepatocellular carcinoma, is becoming more prevalent. The two-gold standard curative treatment options are transplantation and surgical resection, but fewer than 20% of patients qualify as surgical candidates due to severe liver disease and/or co-morbidities. For the treatment of HCC that is inoperable, numerous interventional radiological techniques have been developed and thoroughly researched. The treatment of HCC currently heavily relies on interventional radiology. These methods have considerably aided in halting disease development in liver transplant candidates and extending survival in non-candidates. These medicines stand out for their low toxicity profiles, potent tumour response, and preservation of healthy hepatic parenchyma.
REVIEW ARTICLE | Dec. 15, 2022
Inflammatory Myofibroblastic Tumor of the Gallbladder: A Review of a Potential Pitfall
Shadi Alahmadi
Page no 463-465 |
10.36348/sjpm.2022.v07i12.003
Inflammatory myofibroblastic tumor (IMT) is a unique neoplasm that rarely spreads to other parts of the body. IMT has a wide anatomical distribution, with the mesentery, omentum, retroperitoneum, and pelvis being the most commonly affected. A careful search in the English literature resulted in finding seven cases of IMT arising from the gallbladder. Gallbladder IMT presents a clinical challenge and is preoperatively diagnosed as a malignant gallbladder tumor in most cases. Histopathological assessment is essential for correct diagnosis and management. The prognosis is favorable, with most cases showing no signs of recurrence or metastasis. Even in patients who have had surgical resection, long-term follow-up is required.
CASE REPORT | Dec. 20, 2022
Uterine Smooth Muscle Tumor of Uncertain Malignant Potential – An Unusual Case Report
M. Deepti, L. Krishna, S. Srikanth, C. Swathi
Page no 466-468 |
10.36348/sjpm.2022.v07i12.004
The term smooth uterine muscle of uncertain malignant potential (STUMP) indicates a group of uterine smooth muscle tumors (SMTs) that cannot be diagnosed unequivocally as benign or malignant. Diagnosis, surgical management, and follow-up of this neoplasm remain controversial, especially in pre-menopausal women with fertility desire, due to the non aggressive behaviour and prolonged survival rate when compared to leiomyosarcomas. Studies of STUMP are limited in population and rarity results in few analysis of its fertility outcomes and oncologic prognosis. STUMP has a lower tumor growth rate and recurrence is often delayed by years after initial event compared to high grade leiomyosarcomas which have an aggressive clinical course and behavior thus making it very important to differentiate stump from leiomyosarcomas .Recurrencerate ranges from 8.7% to 11%.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2022
Clinicopathologic Evaluation of Wilms’ Tumor in a Tertiary Care Children Hospital
Parvez M, Ahmed A, Mondal B, Sadiya S, Monowara M, Paul S K, Rashid A
Page no 469-472 |
10.36348/sjpm.2022.v07i12.005
Background and Objective: Wilms’ tumor has been recognized as the most common primary malignant tumor of kidney at childhood. It comprises 5-6% of tumors in the childhood period, and manifests with various clinical symptoms. Since there have been no sufficient studies in this field in Bangladesh, therefore, this study was conducted to investigate its histopathology and different clinical symptoms. Materials and Methods: This study was carried out on existing data from 70 children with a diagnosis of Wilms’ tumor at Bangladesh Shishu Hospital during the years 2015-2020. In this regard, personal and disease-related characteristics of patients including age, sex, tumor stage, histopathology, and involved kidney were evaluated and SPSS software and other statistical tests were used for data analysis. Results: The most common age of disease incidence was 2-4 years. In this regard, male and female ratio was 1.5. Meanwhile, the prevalence of an abdominal mass as the most common symptom was 85.0%. Left kidney was involved in 50% of cases and 58 (82.86%) of patients had a favorable histology. In addition, there was a significant correlation between site of kidney involvement and tumor histology (p<0.005). Conclusion: Considering the achieved advances in the diagnosis and treatment of Wilms’ tumor, early diagnosis with regard to clinical symptoms can have a valuable role in its effective management.
ORIGINAL RESEARCH ARTICLE | Dec. 31, 2022
Clinical and Laboratory Profile in Children with Dengue Viral Infection: A Single Centre Experience
Dr. Hossain Sahid Kamrul Alam, Tania Fardush, Aumol Kanti Banik, Mohammad Rizwanul Ahsan, A.B.M Mahfuj Al Mamun
Page no 473-479 |
10.36348/sjpm.2022.v07i12.006
Introduction: Dengue is a major health problem affecting Bangladesh. The number of cases has increased over the last few years with a large number of populations being children. However data regarding dengue among children is limited. Aim of the Study: Aim of the study was to highlight the most common clinical features and hematological and biochemical findings of patients with dengue fever. Methods: This hospital-based observational study was conducted at the Department of Pediatrics of Dhaka Shishu Hospital, Dhaka, Bangladesh. The study was carried out from 15th May to 14th Octobar 2022 with 220 patients. Result: Total 220 children were enrolled in the study. There was a slight male predominance where male constituted 125 (56.81%) of the study group, while female was 95 (43.19%). That gave a male to female ratio of 1.18:1. Out of 44 cases of raised prothrombin time dengue fever consists of 14 (31.82%), 28 (63.64%) cases of dengue Fever with warning and 2 (4.55%) of severe dengue. In our study 26 (21.7%) cases had complication that was more common in age group of less than of 4 years (31.8%). In our study, complication of dengue was more common in dengue with warning sign (35.6%). In our study 44 (18.63%) cases have complication that is more common in age group of less than of (5-8) years. Conclusion: Hepatic involvement is more common in severe dengue associated with significant rise of liver enzymes. Hepatomegaly is the most important clinical sign but alteration of liver profile can occur with or without hepatomegaly.