Acne vulgaris is a common dermal ailment which is reported globally. Currently, a cross sectional survey (manual and online) in selective districts of Punjab region was conducted and it was concluded that disturbance in sebum production and frequent blockage of skin pores occur due to different potent factors which include improper dietary habits, side effects of medication, genetic complications, environmental conditions and lack of awareness of personal hygiene. Thus the future research efforts should be channelized to ensure provision of low coat and side effects free local pharmacognosal products for acne treatment along with its programmed general public awareness.

Hemangiomas are one of the most common benign soft tissue tumors. Vascular tumors of the female genitalia are unusual and pedunculated vulvar hemangiomas are extremely rare .Usually they are asymptomatic and quite small in size. Here we report a rare case of pedunculated vulvar hemangioma in a 46 year old patient who presented in the gynecology department with a painless mass in vulva for duration of 2 years.

Myxoinflammatory fibroblastic sarcoma (MIFS) is a malignant mesenchymal tumor most commonly occurring in the distal extremities of adults, it generally behaves like a low-grade tumor but is still able to progress locally and metastasize to distant sites, rarely resulting in death. It is a tumor whose unusual morphology can lead to misdiagnosis, either in the non-neoplastic sense (infectious or inflammatory) or as another sometimes malignant tumor entity. The genetic abnormalities detected in MIFS are the t(1;10)(p22:q24) translocation, with rearrangements of TGFBR3 and MGEA5 genes associated with increased levels of FGF8, with chromosome 3 marker/ring formation, and amplification of the VGLL3 locus.

Involvement of the ovary with malignant lymphoma is a well-known late manifestation of disseminated nodal disease. Primary ovarian Burkitt lymphoma is very rare and mainly affects young children. We present a case of a 25-year old woman at 37 weeks pregnant with sporadic Burkitt lymphoma who presented as having ovarian cancer. The patient was managed via elective cesarean section and unilateral oophorectomy. Histopathological examination and immunohistochemical stains were carried out, revealing non-Hodgkin B-cell Burkitt lymphoma. After the diagnosis, the patient was referred to the oncology center for chemotherapy.

Introduction: to compare the clinical, biological, and evolutionary profiles of sepsis with multi-drug resistant and non-multi-drug resistant bacteria in the newborn population. Methods: we performed a prospective, observational, comparative study to monitor all the episodes of blood stream infection, received from the neonatal intensive care, from June to December 2019. Collected data included demographics, symptoms at the time of sepsis, laboratory values, microbiologic results, preliminary and final outcomes. Results: Out of 219 positive blood cultures, 93 episodes were retained. The median age was 6,66 days, 63.4% of newborns were male and 62,4% were premature, 39% of whom had a gestational age of less than 34 weeks. Multidrug-resistant (MDR) bacteria caused 68 sepsis episodes, while non-MDR resistant bacteria caused 25. Bacteremia with MDR organisms, in comparison with non-MDR organisms was associated with poorer preliminary outcomes after empirical antibiotherapy (14% vs 32%; P= 0,001), higher overall mortality rate (20% vs. 51%, P =0.003), and longer antibiotic intake (9.84 vs 7.56 ; P=0,02). The major risk factor found is prematurity (70% vs 40%, P<0,001), No statistical significance was found when other clinical features or laboratory values were compared for infections with MDR vs. non-MDR bacteria. Conclusion: Septicemia with MDR bacteria is more common than non-MDR one in NICU, and it is related to higher morbidity and mortality rates.

Introduction: Brain tumors are the most common tumor of the childhood and the second most common malignancies after haematological malignancies. Childhood central nervous system (CNS) tumors differ significantly from adult brain tumors in reference to their sites of origin, clinical presentation, tendency to disseminate early, histological features and their biological behaviour. Aims and Objective: Analyse the Clinical and histopathological spectrum of brain tumors, in pediatric patients ≤18 year of age. Materials and Method: This was a cross sectional study conducted at the department of pathology, SMS medical college, Jaipur from January 2020 to October 2021. This is a laboratory based descriptive type of observational study and data of brain tumors in children equal or less than 18 year of age procured and their clinico-histopathological spectrum were analyszed. Result: In our study, Out of 116 patients 51.8 % were male and 48.2 % were female. Mean age for the male cases were 10.11 and for female cases were 9.78. we observed intracranial pediatric tumors 67 cases (57.7%) were located in infratentorial region and 49 cases (43.3%) were located in supratentorial region and incidence for intracranial tumor was 39(33.62%) cases of astrocytomas followed by 25 (21.55%)cases of medulloblastoma, 20 (17.24%)cases of ependymoma, 13 (11.20%) cases of craniopharyngioma, 5 (4.31%) cases of pituitary adenoma, 4 (3.44%) cases of meningioma, 3 (2.58%) cases of embryonal and choroid plexus tumor, 2 (1.72%) cases of ganglioglioma and 1 (0.86%) case of Schwannoma and PNET. In this article, Based on tumor location, the symptoms of CNS tumors on the supratentorial region were headache (22 cases, 44.8%), impaired vision (10 cases, 20.4%), seizures (6 cases, 12.2%), vomiting (4 cases, 8.1%). Symptoms of CNS tumors on the infratentorial region were headache (48 cases, 71.6%), vomiting (5 cases, 7.4%), impaired vision (4 cases, 5.9%), seizures (3 cases, 4.4%). Conclusion: Infratentorial cases, maximum number of cases were medulloblastomas and supratentorial cases, maximum number of cases were astrocytic tumours. Overall astrocytic tumours in all senses constituted the most common group of CNS tumours. Within astrocytoma, low grade astrocytoma (grade I & II) was most common CNS paediatric tumour.