Squamous cell carcinomas represent approximately 90% of cervical cancers. Squamous cell carcinoma with sarcomatoid differentiation is a rare histological variant with a very limited number of cases reported in the literature. This entity has been described more frequently in other locations (oral cavity, pharynx, esophagus, skin and larynx). It usually affects postmenopausal women. The histological diagnosis is based on a squamous cell carcinoma fusing with a spindle cell component. Cytokeratin is positive in both components. Because of its rarity, no treatment recommendations are available and it is generally managed as a squamous cell carcinoma of the cervix. We report a case of a 70-year-old female patient presenting an invasive squamous cell carcinoma of the cervix with foci of sarcomatoid differentiation.
July 9, 2021
Incidental and Interesting Pathologies Diagnosed at Autopsy –A Case Series
Dr. K. Subitha
Page Numbers : 240-245
DOI : 10.36348/sjpm.2021.v06i07.002
Background: The role of autopsy is to find out the cause of death, time of death and identify diseases which could have attributed to the death. Autopsy may reveal many histopathological findings which may or may not have been diagnosed ante mortem. A retrospective study of medicolegal autopsies for a period of 2 years was done in a tertiary care centre in Kerala. Clinical findings and ante mortem clinical diagnosis, gross pathological findings and histopathological details were noted. The results were analyzed based on gross findings and histological examination. Histopathological findings which were diagnosed incidentally or co-existing pathology which may or may not have been the cause of death were specifically noted. All the data were analysed using the SPSS software version 17. Results: The present study was based on 212 male and 92 female autopsies. Coronary arterial disease, myocarditis, pneumonia and cirrhosis liver were the common findings. Some of the other pathological findings noted were tuberculosis, burns, pancreatitis, meningitis, encephalitis and cardiomyopathy. There were 6 cases which showed rare and incidental findings. Conclusion: The diagnosis of incidental findings which were not diagnosed ante mortem emphasise the relevance of histopathological analysis in all cases of autopsy .This can also help in epidemiological studies.
Original Research Article
July 12, 2021
Emergence of Diphtheria in Western Part of Gujarat - A Microbiological Case Series from a Tertiary Care Hospital of Rajkot
Dr. Madhulika Mistry, Dr. Arpita Bhattacharya
Page Numbers : 246-249
DOI : 10.36348/sjpm.2021.v06i07.003
Objectives- The burden of diphtheria is more than what it seems to be, so early diagnosis and appropriate treatment is needed to prevent catastrophe. The study is aimed to stipulate the importance of microbiological diagnosis in cases of diphtheria. Thus, we report some confirmed cases from this region. Materials and Methods- 17 clinically suspected cases were studied from October 2020 to February 2021. Two throat swabs were collected. One swab was used for making two direct smears which were subjected to Gram stain and Albert stain respectively. Another swab was inoculated on Nutrient agar, Mac-conkey agar, Blood agar, Chocolate agar and Potassium tellurite blood agar (PTBA). Growths were observed after 48hrs of incubation at 37 o C aerobically. Colonies isolated from PTBA were subjected to Gram stain and Albert’s stain. Results- 6 out of the 17 cases showed positive growth on PTBA. Macroscopically grey-black opaque colonies were obtained. Microscopic examination of the Gram-stained smears showed gram positive, pleomorphic, club shaped bacilli with L and V patterns. Albert’s stain showed green colored bacilli with bluish-black polar metachromatic granules. Conclusion- Awareness among people, widespread universal immunization coverage, availability of modern microbiological support and rapid early diagnosis are the cardinal steps to control diphtheria resurgence.
July 23, 2021
Agriculture and Plant Sciences Based Aspects of Chickpea and Its Importance as a Potential Crop in Plant Sciences
Asia Arooj, Sidra Faiz, Javed Anwar Shah, Amina Ramzan, Muhammad Ihsan, Muhammad Saleem, Muhammad Sheeraz Javed, Sohail Ahmad
Page Numbers : 250-253
DOI : 10.36348/sjpm.2021.v06i07.004
The pulses such as chickpeas or garbanzo beans, lentils and the dry peas, are progressively being documented for their major role in health promotion. Chickpea is reflected as a unique due to the presence of higher level of protein (40%) in it. The drought stress is the major cause of reduction of growth of plants by disturbing the molecular, physiological and the biochemical processes like ion uptake, respiration, signaling pathways, photosynthesis, and induction of hormones, nitrogen assimilation, carbohydrates and the amino acids metabolisms. Nonstop decrease in the productivity of chickpea is indorsed to inadequate genetic variations and the different stresses. Chickpeas comprise a soluble fiber called raffinose, a kind of oligo-saccharide which is fermented in colon through the useful bacteria called the Bifidobacterium. There are some earliest investigations which demonstrate that the individuals eating chickpeas can lesser their danger for diabetes. Chickpeas also play a vital role in the diet of those people who are effected by osteoporosis for its prevention. The protein ratio to starch can be adjusted to target definite textural characteristics of textured pea-protein to closely mimic the various products of meat such as chicken, beef and fish. . Not only do chickpeas produce a valued crop but at the same time they also are responsible for a natural organic technique of breaking disease cycle in barley and wheat crops.
July 23, 2021
Enlarging Retroperitoneal Mass after Chemotherapy in Mixed Germ Cell Tumor of Testis: Growing Teratoma Syndrome
Shanthi Vissa, N. Rukmangadha, Aruna K Prayaga, Venkatarami Reddy V, B. Swathi
Page Numbers : 254-257
DOI : 10.36348/sjpm.2021.v06i07.005
Back ground: Growing teratoma syndrome is a rare entity characterized by growing tumor mass in different locations (like retroperitoneum, abdomen, pelvis, liver, chest, bone, or lymph nodes) in patients with non-seminomatous germ cell tumors of ovary or testis, during or after chemotherapy. Tumor markers will be normal. Histopathological examination confirms the diagnosis. Case report: We report a case of 29 years old male presenting with slow growing retroperitoneal mass after complete treatment for non-seminomatous germ cell tumor of testis. Conclusion: Growing teratoma syndrome occurs in patients with non-seminomatous germ cell tumors and have serum tumor markers with in normal limits. Early diagnosis of this condition helps for complete curative resection of the tumor for better prognosis.
Original Research Article
July 27, 2021
Mycosis Fungoides in UAE
Hamodat Mowafak M, Al Maashari Raghda S, Al Zaabi Eiman
Page Numbers : 258-260
DOI : 10.36348/sjpm.2021.v06i07.006
Primary cutaneous lymphomas (PCL) are defined as extranodal non-Hodgkin Lymphomas . Among the cutaneous lymphomas, nearly two-thirds are of the T cell type with Mycosis Fungoides (MF) being the most common T cell lymphoma (CTCL) . We will be reviewing the incidence, risk factors, prognostic factors, radiology findings, staging and treatment of the disease. To our knowledge this is the first study of its kind to be conducted in the United Arab Emirates (UAE).