ORIGINAL RESEARCH ARTICLE | March 22, 2022
Antibacterial Activity of Silver-Conjugated Magnetic Iron Oxide Nanoparticles
Abiola Olanike Adesina
Page no 23-28
Silver-conjugated magnetic iron oxide nanoparticles (Ag-MNPs) were successfully synthesized and characterized and its effect on certain bacteria was evaluated. The synthesized nanoparticles were tested against six isolates which include Serratia marcescens, Staphylococcus aureus, Escherichia coli, Enterobacter cloacae, Salmonella enterica and Acinetobacter baumannii. The result showed that antibacterial activity of the synthesized Ag-MNPs was found to be effective against Serratia marcescens and Staphylococcus aureus, while the compound was ineffective against some clinical bacterial isolates. The diameters of the zones of inhibition were found to be 20 mm and 27 mm for Serratia marcescens and Staphylococcus aureus, respectively. The Minimum Inhibitory Concentration (MIC) was 10 mg/ml for both organisms. Also, the Minimum Bactericidal Concentration MBC for the two organisms was found to be 20 mg/ml. Therefore, the synthesized compound has antibacterial activity and could be a reliable compound of choice for treating bacterial infections.
ORIGINAL RESEARCH ARTICLE | March 25, 2022
Evaluation of the antioxidative properties of different Fractions of Ethanol extract of Jatropha tangorensis
Unegbu, C. C, Ajah, O, Nnaoma, I. E, Joseph, R. C
Page no 29-32
The antioxidant potential of crude ethanolic as well as ethyl acetate and n-hexane soluble fractions of Jatropha tanjorensis which is widely used in indigenous system of medicinal for different purposes were studied. The antioxidant potential of extract different Fractions were evaluated using different in vitro antioxidant models which includes Ascorbic acid, Beta carotene, flavoniods, total phenols, ABTS, H202, FRAP and reducing power. The estimation of the crude extract showed ascorbic acid (93.51mg/kg), beta carotene (10.564mg/kg), flavoniods (7.88mg/kg), total phenols (64.03mg/kg), ABTS (64.21%), H2O2 (6.39%), FRAP (0.221µmol/ml) and Reducing power (2.913µmol/ml). That of ethyl acetate fraction and n-hexane fractions for Ascorbic acid, beta carotene, flavoniods, Total phenols, ABTS, H202, FRAP and reducing power are as; 227.8mg/kg, 9.21mg/kg, 0.59mg/kg, 33.94mg/kg, 96.47%, 2.5%, 1.1911 µmol/ml, 4.500µmol/ml and 228.7mg/kg, 9.21mg/kg, 0.59mg/kg, 33.94mg/kg, 98.93%, 2.32%, 1.578µmol/ml, 4.456µmol/ml respectively. However, the result of this Study reveals the plant contains some appreciable amount of the antioxidant models analyzed which is vital to illnesses associated with oxidative stress thereby revealing that the plant is a good source of natural antioxidant.
ORIGINAL RESEARCH ARTICLE | March 30, 2022
Synthesis and Characterization of Activated Carbon Prepared from Jute Stick Charcoal for Industrial Uses
M. Nurul Islam, Jahid Sarker, Ayesha Khatton, S. M. Mahruf Hossain, Helena Akhter Sikder, Rashed Ahmed, A. M. Sarwaruddin Chowdhury
Page no 33-39
Activated Carbons (ACs) were prepared from jute stick charcoal by chemical activation using H2SO4 and H3PO4 ranging temperature from 3000C to 3500. The activated carbons and charcoal prepared from jute sticks were characterized by evaluating the surface chemistry, structural features and surface morphology. The properties of the carbons were characterized by Scanning Electron Microscope (SEM), Brunauer – Emmett-Teller (BET), X-Ray Diffraction (XRD) and the FT-IR method. The jute sticks were converted to activated carbons with the highest surface area (135–245m2/g) and largest mesopores volume (0.14–0.16 cm3/g). The FT-IR spectra exhibited that the pyrolysis of jute stick resulted in the release of aliphatic and O - containing functional groups by thermal effect. However, the release of functional groups is effect of chemical reaction in the ZnCl2, H3PO4, and H2SO4 activation process. A honeycomb carbon structure in activated carbon was formed as observed on SEM images. Although charcoal and activated carbon were prepared at 3000C to 3500, the activated carbon exhibited much lower Raman sensitivity due to the formation of condensed aromatic ring systems. Due to high surface area and high porous structure with abundance of functional groups, the activated carbon prepared from jute sticks charcoal absorbed molecules with much higher than those of other activated carbon.