Acute myeloid leukemia (AML) is a very heterogeneous group of hematological malignancies, Characterized by clonal proliferation of abnormal myeloid precursors and altered normal hematopoiesis. The world Health organization (WHO) classification retains the diagnostic threshold the infiltration of the bone marrow by more than 20% of non-lymphoid blasts. AML 2 represents 30% to 40% of AML, the translocation (8; 21) is identified in 5% to 10% of all AML cases and 10% to 22% of AML2 cases. We report a case of AML 2 discovered in a 56-year-old woman, during a paraclinical assessment of acute pancreatitis. The hemogram showed a pancytopenia. The blood smear revealed the presence of circulating blasts estimated at 36%. The medullogram revealed a medullary invasion by undifferentiated blast cells estimated at 59%, Myeloperoxidase staining was positive. The patient was given antibiotic therapy and rehydration. An extra-renal treatment was performed due to the installation of acute renal failure. Evolution was marked by death following infectious complications

In the present study an investigational work was performed to find out the effect of population density on the breeding of domesticated zebra finch. For the present experiment three different types of cages were used namely: type A, type B and type C cages. Type A cage was utilized for colonial breeding of zebra finch. Ten adult compatible pairs of zebra finches were kept in type A cage. Five type B cages were built for the study; two adult compatible pairs were kept in each type B cage. Ten type C cages were constructed for the present study; one adult compatible pair was released in each type C cage. In type A cage 5 pair produced eggs and only one pair hatched and reared chicks successfully. In type B cages none of the pairs produced eggs. In type C cages all pairs produced eggs, hatched eggs properly and reared chicks successfully.

Tuberculosis (TB) is commonly associated with poverty and under-nutrition in both developed and developing countries. Being underweight has been associated with a higher risk of tuberculosis in several studies. A retrospective descriptive study was conducted to analyze TB surveillance data from the chest clinic teaching hospital Batticaloa, in SriLanka. Finally, 103 TB patient’s records were analyzed and available data were extracted. The prevalence of underweight among TB patients is 39(37.9%). Obesity and overweight were associated with a significantly lower risk of both clinically active and culture-confirmed tuberculosis

Phytochemical study of medicinal plants is essential to determine the presence of active constituents in them. Alkaloids, the largest class, are the most important from medicinal point of view. Alkaloids are low molecular weight nitrogen containing compounds and are typically alkaline. Approximately more than 2000 alkaloids have been isolated so far. They are found in those plant parts where there is great vitality and growth. The medicinal use and their biological source along with family has been discussed in their review.

This study was designed to examine the relationship between organisation design and organisational effectiveness in the Nigerian construction industry. The population of this study was the entire managerial staff population of Julius Berger Nigeria Plc and Setraco Nigeria Limited, both construction companies in Nigeria. The study adopted the survey research design and copies of structured questionnaire were administered to a sample of 341 respondents. Proxies for organisation design were drawn from Kates and Galbriath “Star Model” of organisation design. Descriptive statistics were used to analyse the data, while simple linear regression analysis was used to test the hypotheses formulated for the study. The findings of this study indicate that the five elements under study have strong positive relationship with organisational performance. Consequently, it is recommended that management of organisations in the Nigerian construction industry should consider all five elements when designing or re-designing their organisation.

Determination of antibody titre of dogs vaccinated against canine distemper in Jos North and South local Government Areas of Plateau State was carried out by collection of sera of vaccinated dogs and administration of wellstructured questionnaires to dog owners. The samples collected were analyzed using the immune-blot ELISA Kit to determining the antibody titre (immunoglobulin G). It indicated that dogs vaccinated against the disease mounted adequate protective immunity. The result revealed that 54 (90.0%) of the sampled dogs have protective immunity, with those given more than one dose having higher level of protective antibody. Statistically, the result showed that the antibody titre did not differ significantly in relation to immunity and sex, breed, age and location but significant difference was seen in relation to number of primary vaccination. The result also revealed that those dogs that received booster doses (secondary vaccination) had more protective antibody. The study was aimed at evaluating the antibody titre of dogs vaccinated against canine distemper in Jos, Plateau State.

This study aimed to study the effects of age and body mass index on infertility, preovulatory endometrial thickness, and pregnancy outcome after ovulation induction/intrauterine insemination. Twenty unexplained infertility women and thirty polycystic ovary syndrome women subjected to ovulation induction/intrauterine insemination were enrolled in this study. Only two polycystic ovarian syndrome women (4%) became pregnant. There was significant effect of age on endometrial thickness for unexplained infertility and polycystic ovarian syndrome women (P=0.02, P=0.05, respectively). Body mass index and endometrial thickness were independent factors for unexplained infertility and polycystic ovarian syndrome women (P=0.26, P=0.4, respectively). Age adversely affected endometrial thickness while body mass index was not correlated with endometrial thickness

Competitive business environment organizations are facing today has prompted them to develop business strategies geared to improve performance in order to sustain competitive advantage. However choice of strategy alone cannot guarantee performance without considering the role of macro environment in that relationship. The study therefore sought to establish the moderating effect of macro environment factors on relationship between combined strategy choices and performance. Over and above the direct effect that moderating factors (macro environment factors) may have on company performance their moderating effects on the relationship between strategic choice and performance were tested. Overall, it can be concluded that the four components of company’s macro environment manifest and affect strategy-performance relationship in varying degrees. The findings imply that companies are environment dependent and to manage this company-environment interface, an appropriate strategy choice is necessary. The study also presents a clear link between environment-strategy-performance such that managers of such companies should consider in enhancing company survival and growth.

In a preliminary research, the authors reported that solvents extracts of Alstonia boonei (Egbu) possess strong antimalarial activity against NK-65 Chloroquine sensitive Plasmodium berghei infected mice with aqueous extract having the highest decrease in mean percentage parasitaemia. This research is therefore aimed at evaluating the acute and sub-chronic toxicity of solvents extracts of the plant on kidney. The (LD50, oral) was conducted in two phases. In the first phase, oral doses of 10, 100 and 1000 mg/kg body weight of the extracts were administered and mice observed for sign of toxicity and death. In the second phase, 1600, 2900 and 5000 mg/kg body weight of the extracts were administered and signs accompanying toxicity and possible death of animals were also monitored. Sub-chronic toxicity studies were carried out to assess the effect of the solvents extracts on kidney function indices after 28 days of oral administration of the extracts at 150, 250 and 500 mg/kg body weight. The (LD50, oral) of all extracts was found to be greater than 5000mg/kg which is practically non- toxic according to standard scale of toxicity. The result of sub-chronic toxicity study showed a significant increase (P<0.05) in mean levels of creatinine, urea and serum electrolytes in all extracts administered groups in a dose dependent pattern compared to normal control. However, histopathological analysis of the kidney tissues shows no pathological changes between test groups and normal control. Thus, solvents extracts of Alstonia boonei modifies biochemical parameters (Crea, Urea and Electrolytes) but within the context of duration of this research, no significant pathology was observed in kidney tissues. Alstonia boonei stem bark should be used with caution

Nutritional and industrial processes have increased the demand of oils and this in turn has led to the search for oils from different types of seeds for possible development and use. It is in this vein that the Tetracarpidium conophorumfruit nuts were extracted with n-hexane (soxhlet extraction at 650C). The proximate composition,antinutrient and mineral content of freshly harvested Tetracarpidium conophorum(African walnut)seed from 4 weeks after anthesis (WAA) to fruit maturation were assessed in this study. Data obtained for the proximate composition at matured stage of fruits developmentrevealed significant high amount of fat(43.4±0.82) %; moisture(36.7±1.39) %; crude protein(30.1±1.38) %; carbohydrate (16.91±1.07) %;low crude fibre (2.59±0.64) %, and ash content(7.3±0.07) %[which contained higher amount ofminerals such as of Fe (130.81 ± 3.8) ppm, Mn (40.11 ± 1.00) ppm, Ni (2.92 ± 0.81) ppm, and Cu (12.01 ± 0.71) ppm, decrease inCa (1.082 ± 0.08) %, Cr and Cd were not detected throughout the period] at 20 WAA compare to immature stages of 4, 6, 8, 10, 12, 14 and 16 WAA. The level of antinutrientfactors are oxalate (0.46±0.05) mg/100g; Phytate (29.2±0.44) mg/100g and cyanogenic glycosides (0.17±0.07) recorded lower content, except tannins (90.5 ±3.93) mg/100gwhich recorded significant (p < 0.05) higher content at 20 WAA when compared with immaturestages in 4, 6, 8, 10, 12, 14 and 16 WAA. This study revealed the nutritional profile of the fruitnut as good sources of plant protein, carbohydrate and fat, with reduction in the level of some anti-nutrients in matured fruits which are potentials that could be exploited by food and pharmaceutical industries.

Nurses are facing practice problems that causes disturbing and stressful situation. The most common and prevalent issue is moral distress. Moral distress is affecting performance of professional nurses at health care setting. Cross-sectional study design was used. Questionnaire consisted on 5 point Likert scale adopted was used to know the impact of moral distress on nurse’s performance with sample size 187 Nurses from Public Hospital Lahore. Finding of the study shows that there is a significant negative (reciprocal) impact of moral distress on performance of nurses The current study concludes that moral distress decrease the job performance of the nurser’s at hospital settng. This study revealed the negative relationship between moral distress and nurses’ performance. The study findings will enable the health care organizations to enhance the performance of staff nurses by minimizing the factors that are causing moral distress among nurses. Hospital can arrange workshops and education sessions to give awareness to deal moral distress situations

The antioxidant properties of oil and fruit extracts of Tetracarpidium conophorum (African walnut) from four weeks after anthesis(WAA) to fruit maturation were assessed in this study. The oils from the fruits were extracted with chloroform-methanol 1:2 (v/v), and the methanol extracts of the fruit seeds were also prepared using standard procedures. The in vitro antioxidant capacity of the fruits and oil extracts was determined by spectrophotometric methods using 2, 2-diphenyl-1- picrylhydrazyl (DPPH) radical, H2O2 and malondialdehyde (MDA) assays. Results from the study indicated that DPPH and H2O2 scavenging capacity as well as percentage inhibition of MDA were significantly (P˂0.05) higher inoil 20 WAA (48.34±0.12%,46.9±1.03%,53.5±0.46%)and whole fruit extracts at 20 WAA (31.84±0.33%, 19.0±1.12%, 51.7±0.26%) respectively,but with significant (P˂0.05) lesser percentage of inhibition at 4-12WAA in both the oil and the whole extracts. The hepatoprotective effects of the extracts were examined in vivo in male wistar rats challenged with sodium arsenate. Results showed that the rats fed with the oil and whole fruit extracts had significant reduction (p<0.05) in lipid peroxidation, increase in superoxide dismutase (SOD) and catalase (CAT) activities especially at 16-20 WAA relative to control values. African walnutextracts treated rats also showed similar decrease in serum AST (122.7±2.58U/L), ALT (59.1±2.49U/L), ALP (20.4±0.15U/L) and GGT (229.0±0.36U/L) levels at 20 WAA when compared to 4 WAA extracts treated rats, AST (129.3±0.64U/L), ALT (72.3±2.59U/L), ALP (34.4±0.08U/L) and GGT (299.7±1.27U/L). The results suggest that the various fruit extracts possess varied degrees of potent antioxidant activity both in vitro andin vivo and may serve as important sources of antioxidants in food, cosmetics and pharmaceutical industries.

Maternal nutrition during pregnancy has been associated with healthy outcomes for both mother and child. This study investigated the factors influencing the nutritional practices of pregnant women attending antenatal clinic at a State Hospital in Ogun State, Nigeria. Study employed a descriptive, non-experimental research design. A non-probability convenience sampling method was used to select 210 pregnant women and questionnaires were administered after obtaining ethical approval and written consent. Data obtained was analyzed using Statistical Package of Social Sciences (SPSS 22.0. version). Inferential statistics of chi-square was used to test the hypothesis at a significant level of 0.05. Findings revealed that the nutritional practice of participants is inadequate. Although more than half of the participants (52.9%) claimed they eat whenever they felt like, only 29.8% respondents eat variety of food in moderation whereas 43.4% respondents eat fruits and vegetable daily. 82.2% respondents confirmed that they forbid the intake of certain food item when pregnant. Factors that hindered women from maintaining adequate nutritional practices in pregnancy includes low socio-economic status (42.4%), inadequate knowledge about the food item (20.4%), ignorance (13.1%), lack of husband support (12.6%) and forgetfulness (11.5%). Provision of health information was identified as a key measure for improving nutritional practices of women during pregnancy. Nutrition education and counselling given during each antenatal visit should be intensified. Special programs which elicit husband support should be organized in order to increase men’s knowledge of adequate nutrition intake in pregnancy and also enhance supportive care which would positively affect women’s nutritional practice.

This work discussed expression of the energy and millennium relativity of energy in Einstein generalized special relativity and pression of direct modification of Newton kinetic energy by using Taylor series he four vectors energy momentum of total energy formula is derived through energy relation and Lorontz transformation.

The involvement of the ovary by malignant lymphoma is a well-known late manifestation of disseminated nodal disease. Primary ovarian lymphoma is rare. We report a case of primary ovarian non-Hodgkin’s lymphoma with unilateral involvement which was managed by surgery and chemotherapy. A 42-year-old woman was admitted with signs and symptoms suggestive of an ovarian cancer. Computed tomography revealed a tumor of the left ovary measuring 12 cm in diameter, without enlarged lymph nodes. The tumor was classified as a diffuse large B-cell lymphoma. The patient has been advised 6 cycles of CHOP regimen and is presently on treatment. She has now been without disease for 36 months after the surgery. According to previous reports the treatment principles and prognosis of primary ovarian large b-cell lymphoma is the same as that of other nodal lymphomas