The retro-lunar carpal dislocations are often under-diagnosed in the emergency services by the lack of knowledge of the pathology. The modalities of taking care of the lunations are still discussed; if the surgical treatment is now unanimous because it alone can limit residual carpal instability, bone necrosis or osteoarthritis. Many remedial techniques have been proposed, although controversial, the authors agree that a maximalist open-minded attitude gives the best results. Our work presents the results of a retrospective series of 12 cases of retro-lunar carpal dislocations. We will discuss the epidemiology of this condition, the different types of lesions, therapeutic modalities.

Teaching and learning of English vocabulary are the most basic parts in the whole process of English acquisition. Based on the result analysis of an extensive on-line questionnaire about the vocabulary teaching situation among some Chinese and foreign teachers, this paper points out the existing problems in college English vocabulary teaching and learning. The corresponding vocabulary learning strategies are proposed to stimulate students' interest in English vocabulary learning, enhance the flexibility of vocabulary learning and use, and thus improve the effect of English vocabulary teaching and learning.

With an objective to develop some potent, novel and less side effect having antitubercular agents here we have synthesized a series of substituted/ unsubstituted 2-phenyl tetrahydroquinoline derivatives (IIa-g). These were obtained by the reaction between substituted 2-phenyl-1, 2, 3, 4- tetrahydroquinoline and sulphur in acetonitrile. Structure of the newly synthesized compounds were confirmed on the basis of physico-chemical and spectral data (IR, 1H NMR, 13C NMR and Mass). All the synthesized compounds were screened for their antitubercular activity using Microplate Alamar Blue Assay (MABA) method. Among the synthesized compounds II b, II e and II g have shown significant antitubercular activity.

Globalization today is at a dangerous crossroads. Although many alleged it has provided enormous benefits, but the systemic risks and growing inequality it causes necessitate urgent action. The myth of a borderless world is crashing down. Traditional pillars of open markets; the United Kingdom and United States are wobbling. This is evident in the Brexit vote which stunned European Union and the world at large, couple with the recent policies of the American government towards its fellow western allies and immigrants. Many people are beginning to feel so troubled about our economic future. The failure to arrest these global developments is likely to lead to growing nationalist policies, protectionism and xenophobia, which the world is already witnessing. Globalization has created growth, no doubt. But what kind of growth? And for who? This crisis posed by globalization has forced many to question the motive behind this phenomenon. Could this be renewed imperialism? This paper adopts rational and analytic methods in exposing this argument.

Fibrous dysplasia (FD) is an uncommon skeletal disorder in which normal bone is replaced by abnormal fibro osseous tissue. Mainly, Fibrous Dysplasia is found in children, and by adulthood it usually becomes quiescent. Our case showed Fibrous dysplasia of 9-year-old female child with port wine stain on the right side of mid face since birth. Our evaluation was that growth in childhood had achieved the progressive stage. We presented all radiographic and clinical images of this case that emphasized the diagnosis of the disease.

This research reveals the improvement of Indonesian students’ mathematical problem solving skill taught by problem-based learning with realistic model. Experimental research design was used and the population of the research was junior high school grade VIII students of Muhammadiyah 25 in Rantau Prapat Indonesia. Two classes with 30 students in experimental class I and 30 students for experimental class II were chosen as the sample of the research. Moreover, data found from pretest and postest of experimental class I and II were collected and calculated by Gain Hake pattern. The finding of the research showed that students posttest result after having taught by implementing problem-based learning with realistic media was 82, 08, and students taught by conventional teaching strategy was only 76,35. Furthermore, based on Gain pattern analysis, problem solving skill of experimental class I was higher with 0,61 than students taught by implementing conventional teaching strategy with only 0,46. Then, based on t-Test it was found that students’ problem solving skill with tobserved= 3,961 and t table = 2,00. In other words, t observed> t table, 3,961 > 2,00. This research conluded that students’ problem solving skill was higher when they were taught by problem-based learning with realistic media.

Cefotaxime is a 3rd Generation Cephalosporin and mainly acts by binding to penicillin-binding proteins and inhibits final transpeptidation step of peptidoglycan synthesis, resulting in cell-wall death; resists degradation by beta-lactamase; proper dosing and appropriate route of administration are determined by condition of patient, severity of infection, and susceptibility of microorganism. Indicated in the various conditions like Gonococcal Urethritis/Cervicitis, Gonorrhea, Rectal, Infections Caused by Susceptible Organisms, Prophylaxis of surgical infection. A child of 5 years old of male patient came to pediatrics department with chief complaints of seizures and admitted in pediatrics department-II and his treatment chart was phenytoin 100mg PO BD and valproic acid 200mg – 200 mg – 300 mg Po OD. During his second of treatment child developed fever of 1020F and to reduce the condition physician prescribed cefotaxime 500mg BD IV on 4th day of treatment child developed macular rash all over the body. Better vigilance is necessary for implementation of safe and effective treatment for each individual patient.in order to prevent serious adverse drug reactions of this drug,close monitoring drug treatment course, creating awareness, recognition of the problem and careful management of all the patients who receive medication are essential, because use of cefotaxime causes Colitis, Diarrhea, Elevated blood urea nitrogen (BUN) and creatinine, Elevated hepatic transaminases, Eosinophilia, Fever, Injection site pain, Nausea, Pruritis, Rash, Thrombocytopenia, Transient neutropenia, Vomiting.

This research focused on the enhancement of Indonesian accounting vocational students’ achievement andcharacter taught by applyingTwo Stay Two Stray model. This model was derived from cooperative learning model that provided the opportunities for students who weredivided into some groups to share and to exchangeboth knowledge and information with other groups. To achieve the aims of the research, quantitative method was used with 2 x 2 ANAVA research design. By applying random purposive samplinggrade X vocational students of SMK Al Washliyah Medan were chosen as the sample of research. There were 32 students for each experimental class I and II. The instruments used for students’ achievement was test, while, questionnaire with Likert scale was used as the instrument of students’ character. Then, all data found were analyzed by using general linear model with SPSS 22 IBM to identify both the score achieved and each indicator of questionnaire related to students’ character and achievement on accounting subject. Based on data analysis, through Kolmogorov – Smirnov with Sig 0.325 <0.05, it showed that all the data were distributed normallyand the data were distributed homogenouslyas well by applying Levene’s test with Fobserved> Ftable (0.639 > 0.05).Furthermore, by applying general linier model with Sig < 0,05 (0,000 < 0,05), it is found that students’ character were not affected by implementing Two Stay Two Stray Model withSig > 0,05 (0,791 > 0,05). Ho was accepted with Sig 0.491 > 0.05 which showed that there was no interaction occured between students’ achievement and character taught by Two Stay Two Stray Model. However,students’ characeter in experiment class 1 was higher than experimental class 2 with some characters’ value built, namely; religious, respectful, honest, discipline, creative, independent, communicative, and responsible.

Hydroquinone (HQ) and clobetasol 17-propionate (17PC) are two medicinal agents commonly incorporated because of their skin bleaching properties into lightening cosmetics sold out in some sub-Saharan regions (Senegal, Togo, South Africa, Cameroon…). The aim of this study was to quantify these agents in lightening creams and body lotions marketed in Douala, the economic capital city of Cameroon. A preliminary investigation was carried out at the main cosmetics sales outlets (pharmacies, perfumeries and supermarkets) of the city, in order to come out the overall proportion of lightening cosmetics and to inventory the mainly bleaching agents listed as ingredients in these products. About forty lightening creams and body lotions were purchased and then analyzed in other to come out their respective hydroquinone and 17PC concentrations. The results have revealed a compliance rate of 79%, with 47.5% of the samples containing hydroquinone at a higher concentration than the one allowed in cosmetics (≤ 2%). Clobetasol 17-propionate, forbidden in cosmetics, has been identified in all the samples with 77.5% having a dosage above the 0.05% accepted medicinal creams, what may lead to systemic repercussions when used chronically.

The article investigated students attitudes towards choosing Information technology and computer science courses in relation to gender. The study adopted an observational, cross-sectional exploration design with both quantitative and qualitative methods of data collection. A structured questionnaire and an interview guides were employed togather information from the respondents. Data was analyzed using frequency tabless. Study findings showed that there was a positive correlation between attitudes of students towards choosing Information technology and computer science course relating it to gender. The study recommended that there is need to advertise and give scholarships to young females to specifically pursue Information technology and computer science courses. There is need to encourage girl child education through the practice of positive discrimination and affirmative action in society. The society should be sensitized on the importance of a girl child so that elimination of gender stereotyping becomes easy. The study also suggests encouraging female candidates to apply for Information technology and computer science course and addressing gender-imbalance through student development programs. Universities should organize workshops or visit secondary schools and complain for a girls to take up Information technology and computer science course and also tell them that it is possible for them to do the course and should be told that Information technology and computer science is not only meant for males only, everyone can do it irrespective of sex and gender.

Diffuse large B cell lymphoma (DLBCL) of the ethmoid sinus is very rare entity. The presenting symptoms are usually similar to those of benign inflammatory diseases. We report a case of a 50-year-old male patient who presented with acute onset progressive proptosis right periorbital swelling, redness and treated initially as periorbital cellulitis secondary to right maxillary and ethmoidal fungal sinusitis, but proven to have be a diffuse large B-cell lymphoma (DLBCL) of the ethmoid sinus. HIV serology was negative. The patient was referred to the department of oncology where chemotherapeutic treatment for the lymphoma. We emphasize the importance of considering primary lymphoma of the ethmoid sinus in the differential diagnosis of periorbital cellulitis and refractory rhinosinusitis, to help in early diagnosis, which can improve prognosis.

Educational systems all over the world have acceptable and justifiable best practices necessary for impartation of knowledge, skills, attitudes, values and modes of thinking to learners by teachers and those who occupy similar positions in society. But it is evident that there are also some objectionable methods employed in the classroom, and similar places, among them are drilling, conditioning, indoctrination, instruction, and so on. This paper casts a critical look at indoctrination: its sources, the necessary conditions for a person to be indoctrinated, and an assessment of indoctrination vis-à- vis education. The paper finally examined the implications of indoctrination for education in Nigeria, and made recommendations to ameliorate perceived deteriorating trend in the system.

Normal-Phase High Performance Liquid Chromatography method was developed for determination of Rapamycin, Temsirolimus Regio isomer (monoester) and Temsirolimus diester in Temsirolimus drug and pharmaceutical formulations. The separation was accomplished on YMC Pack SIL (250 x 4.6 mm, particle size 5μm) column under isocratic mode. The column oven temperature was set at 35° C and Auto sampler temperature used at 5°C. The mobile phase is a mixer of n-hexane, ethanol and trifluoroacetic acid in the ratio of 90:10:0.01 and PDA detector set at 280 nm used for detection. The retention times of Rapamycin, Temsirolimus peak, Temsirolimus monoester and Temsirolimus diester peaks are 12.29, 21.24, 33.11 and 51.91 min. respectively. The method has been fully validated and is linear. Results of analysis are validated statistically and by recovery studies. During the process development of Temsirolimus, three process impurities (Rapamycin. Temsirolimus monoester and Temsirolimus diester) are detected by high performance liquid chromatography (HPLC). This method offers advantages over using photodiode-array UV detection (LC-PDA) for the determination of peak purity, namely components with similar UV spectra can be distinguished, the molecular mass of the impurity can be determined, and structural data can be obtained by using LC-MS. The result of studies shows that the proposed normal phase-HPLC method is found to be precise, linear, accurate, rugged, selective, specific, and robust. Hence this method may be used for the routine analysis in bulk drug and in its pharmaceutical dosage forms.

This paper takes „postgraduate degree authorization evaluation of China University of Geosciences (Beijing) in 2016-2017‟ as an example to analyze the evaluation index system, evaluation process and existing problems of degree authorization institutions in China, and finally proposes corresponding policy recommendations for improvement, in order to provide reference for the qualification evaluation of postgraduate degree authorization units and the construction of students‟ training quality supervision system.

A simple, precise, and rapid ultra-performance liquid chromatography (UPLC) method for the determination of fluoxetine level in human plasma using clomipramine as an internal standard (IS) was developed and validated. Plasma samples containing fluoxetine were spiked with the IS and extracted with hexane and iso-amyl alcohol (98:2,v:v) under alkaline condition. Extracted samples were kept at –80ºC for 10 minute then organic layers were transferred to clean tubes and dried under gentle steam of nitrogen at 40 °C. Residues were reconstituted in 200 µl of 0.05% phosphoric acid and 10 µl were injected in to the UPLC system. The compounds of interest were efficiently separated on 2.1 x 100 mm, Acuity UPLC, C18, steel column (at 30°C) and detected with a photodiode array detector set at 230 nm. The mobile phase consisted of water (pH= 2.4, adjusted with phosphoric acid) and acetonitrile (68:32, v:v) and was delivered at a flow rate of 0.3 ml/minute. No interference in blank plasma or by norfluoxetine or commonly used drugs was observed, and the detection limit of fluoxetine was 0.005 µg/ml. The relationship between fluoxetine concentration in plasma and peak height ratio of fluoxetine /IS was linear (R2 ≥ 0.985) in the range of 0.01 –1 µg/ml. Inter-day coefficient of variation and bias ≤ 13.0%, and < 9.4, respectively. Extraction recovery of fluoxetine and IS from plasma samples was ≥ 87%. Using the method, fluoxetine was found to be ≥ 85% and ≥ 89% stable in processed (24 hours at room temperature or 48 hours at -20 °C) and unprocessed (24 hours at room temperature or 23 weeks at -20 °C) samples, respectively.