Etoposide (ETZ) is a standard drug used in treatment of several malignancies. However, it is associated with increased risk of spleen damage and secondary acute myeloid leukaemia. Ginger (Zingiber officinale) is an ancient safe remedy used in management of minor health issues due to being rich in active constituents. Therefore, we hypothesize that ginger oil can ameliorate ETZ-induced oxidative stress and DNA damage in spleen tissues and leukocytes. To achieve our aim, ginger oil (75&150 mg/kg b.w.) was administered three times to male albino rats an hour prior to ETZ oral administration (1mg/kg b.w.) for 3 weeks. Results showed that ETZ induced marked biochemical alterations in the oxidative status of spleen tissues. The elevated lipid peroxidation and nitric oxide levels were statistically countered. However, the glutathione, superoxide dismutase and catalase enzymes were reduced. Moreover, the DNA single strand breaks as evaluated by comet assay in blood leucocytes also showed significant changes. The administration of ginger oil caused significant improvement of oxidative stress status and DNA damage. In conclusion, our results suggest that ginger oil could be used as a herbal remedy for reducing ETZ-induced adverse effects in male albino rats.

The research analyzed lexical aspects which have correlation among the elements in cohesion discourse systematically in the texts of Melayu Deli Folklores. Its objective was to identify and to describe the type of lexical cohesion devices in the texts of the tales, “Hikayat Putri Hijau”, ”Dongeng Batu Belah Batu Betangkup” and “Panglima Nayan”. The analysis was focused on the types of lexical cohesion such as repetition, synonym, antonym, collocation, meronym, and hyponym. The background of the research was LSF (Systemic Functional Linguistics) with the study on the theory of cohesion discourse which states that social context can interpret language structure. The research used library research, descriptive qualitative approach, and primary and secondary data. The result of the research showed that there were the aspects of lexical cohesion such as repetition, synonym, antonym, collocation, meronym, and hyponym, and the most dominant aspect.

One cannot hold a company directly liable for any criminal act until one identifies the very ego and center of the personality of the company. This paper is, therefore, concerned with the examination of the provisions made under our laws and the laws of other jurisdictions together with case laws for easy identification of those organs of the company which control the affairs of the company. The author adopted historical, expository, analytical and comparative methods in conducting this research. Part of the findings of this paper is that the de facto control of the management of the affairs of a company resides with the board of directors while de jure control is with the general meeting. The paper, recommends that Sections 246 and 255 of CAMA be amended to accommodate the right caliber of men on the board.

The research discusses the profile of Indung in Sundanese society, namely Sunan Ambu, Dewi Sri, and Ronggeng. It is conducted as an effort to unravel the existence of woman as indung or mother that has been influencing many aspects of life of Sundanese society. All those three actors have very dominant role both in social and internal aspect. The figure purpose of the research is to identify the process of value change in a series of time, particularly the change in their function caused by the particular circumstances during the past colonial era. The research employs descriptive-analytical methodology with qualitative approach, and focuses its analysis on process, event and authenticity. The findings of the research suggests that either the of Sunan Ambu, Dewi Sri or Ronggeng, have a multi-dimensional character: namely (1) as a woman who is responsible for human kind‟s life sustainability, (2) as a mother or indung, (3) as a protector and life-giver, the character of which are deeply embedded in those three figures. Those characters are manifestation of”the existence and identity of Sundanese woman” that always inspire the true meaning of life for the human kind.

The existence of the media and ideology is akin to two sides of a coin. This existence is characterized by interrelatedness and mutual influence. During the Presidential Election of 2019, partisanship became a prominent issue. The media was regarded as being partisan and supportive of the incumbent. Similar case was observed during the Presidential Election of 2014 where the author identified the partisanship of the daily the Jakarta Post toward one of the presidential candidates. This stance is reflected on the editorial of the Jakarta Post entitled Endorsing Jokowi. Through this editorial, the Jakarta Post established itself as the only daily that openly threw its support for one particular presidential candidate. The analysis of this research is based on the Critical Discourse Analysis developed primarily by Teun Van Dijk in order to identify the reasons and means employed by the Jakarta Post to demonstrate its partisanship. The choice of theme, outline, diction, vocabulary and sentences used in this editorial reflects the attempt to marginalize, trivialize and accost the other candidate. In addition, the editorial contributed in providing insight on the candidate and the unfolding event. The research also identified the ideology espoused by the Jakarta Post which included pluralism, human rights, civil society and Reformasi which influenced their stance toward partisanship in this daily. Two events that took place during the campaign, which include the bestowal of the title Islamic Commander in Chief and the proliferation of the use of memes as the form of people’s political expression are observed as the social context that spurred the publication of such editorial.

Government institutions such as the National Police of the Republic of Indonesia have given attention to the process of implementing public information disclosure by issuing several regulations. Regulations concerning public information services were issued by the agency since 2010, which were later, renewed in the regulation of the Head of the National Police of the Republic of Indonesia number 24 of 2011. Changes to the new regulation are the result of revision of regulation number 16 of 2010 concerning the public information service in the police force of the Republic of Indonesia. Public perceptions related to the quality of service of government institutions that are considered complicated, slow and too many procedures are a challenge for the Indonesian Police Agency. The process of achieving good performance as an indication of the success in the implementation of good governance. According to a survey conducted by the Partnership Governance Index (PGI) regarding the quality of the principles of good governance in Indonesia, data were obtained that based on the dimensions of the principle of good governance related to the level of government information disclosure, showed a tendency towards poor assessment on aspects of transparency. It is an indication that the public considers the level of transparency of the government and Indonesian bureaucracy needs to be improved and improved. Through the qualitative analysis method, this research is expected to produce a mapping of communication and changes in the development of good governance in the Indonesian National Police. Communication and changes in realizing good governance at the police institution are carried out through POLRI Bureaucratic Reform (RBP) as stated in Map the third wave of the National Police Bureaucracy Reform 2016-2019, which is nothing but the actualization of 8 areas of change in the Apparatus, Supervision, Accountability, Mental fields. Institutional, Management, Human Resources Apparatus, Legislation and Public Services, which confirms the importance of implementing clean government and good governance that are universally believed to be the principal needed to provide excellent service to the community, with the main program being carried out by the government to build state apparatus through the application of bureaucratic reform.

Indonesia is the largest Muslim country in the world followed by India in second place and Pakistan in third place [1], so that the majority of the population should understand the Arabic so that they will be able to read the Qur'an properly and correctly. The daily conversation learning process using Arabic we will use the android media application with the Multimedia Development Life Cycle (MDLC) research method and the Fisher-Yates Shuffle algorithm to perform a random process of problem training. At the stage of storyboarding using Belsamic Mockup tools, while collecting materials for images, sounds, text can be obtained free of charge or by ordering to other parties in accordance with the design made in the previous stage.

In OBG out-patient department abnormal uterine bleeding (AUB) is one of the commonest presenting symptoms. This condition is caused by a variety of systemic illnesses or it may be related to pregnancy, polyps, fibroids, adenomyosis, anovulation or neoplasia. Endometrial biopsy could be used as the first diagnostic step & it is effectively qualitative in AUB. This study was done for evaluation of spectrum of lesions of endometrium by histopathology and to find the cause of AUB, in different age groups.

Objective: To study the role of IgM enriched IVIg in reducing mortality in neonatal sepsis. Method: It is a prospective randomized study conducted in Special Newborn Care Unit(SNCU) of CNMCH, Kolkata over a period of two years (June 2016 – May 2018).Two groups of 248 newborn each (matched for gestational age, sex, weight and other variables) were randomly allocated to receive either antibiotics alone (control group) and antibiotics plus IgM enriched IVIg intravenously (5ml/kg/day) for 4 days(Immunotherapy Group). Result: Mortality from sepsis in control group was 88/248 (35.5%) of which death from culture proven sepsis was 70/182 (38.5%) and culture negative sepsis was 18/66 (27.3%).In immunotherapy group overall mortality was 40/248(16.1%) of which death from culture proven sepsis was 32/192 (16.7 %) and culture negative sepsis was 8/56(14.2%).Conclusion: We conclude that IgM enriched IVIg therapy in conjuction with antibiotic significantly reduces mortality in neontal sepsis,particularly in culture positive cases.

Background: Breast diseases are showing a rising trend. The present study was conducted with aim of Clinicopathologic analysis of Breast Lumps. Materials & Methods: The present study was conducted on 130 breast specimens obtained from surgery department. The method of biopsy used was either open (excision and incision) or tru-cut needle biopsies depending on size and clinical parameters at presentation. Results: Maximum patients were seen in age group 40-60 years (70) followed by 20-40 years (40) and >60 years (20). Histological diagnosis was fibroadenoma in 49, fibrocystic disease in 20, benign phyllodes in 11, duct ectasia in 6, chronic mastitis in 15, granular cell tumour in 10, neurofibromas in 2, lactating adenomas in 4, lipomas in 6 and invasive lobular carcinomas in 22. Maximum masses were seen in upper inner quadrants (30%) followed by lower outer quadrants (24%), upper outer quadrants (12%), entire breast (11%), lower inner quadrants (10%), central (8%) and middle quadrants (5%). The difference was significant (P< 0.05). Conclusion: Most common breast mass was fibroadenoma followed by invasive lobular carcinomas. Most common site was upper inner quadrant.

This study aims to comparative analyze performance ratio of PT. Permata Bank Tbk. The method used in this study is paired t test. The result are Performance of PT Bank Permata Tbk are had 8 data increasing are Minimum Capital Requirement (KPMM), Problematic productive assets and non-productive assets of total productive assets and non-earning, Problematic productive assets against total earning assets, Non-Performing Loan (NPL) net, Return on Assets (ROA), Net Interest Margin (NIM), Return on Equity (ROE) and Loan to Deposit Ratio (LDR ). Ratio Performance of bank are had 3 data decreasing are Reserve for impairment losses (CKPN) of financial assets to earning assets, Non-Performing Loan (NPL) gross and Operational Expenses on Operating Income and (BOPO) but there are not difference significant between Performance Ratio of Bank Permata in 2018 and Performance Ratio of Bank Permata in 2017.

Gastrointestinal lesions are the major group of specimens received in the surgical pathology department. This includes endoscopic biopsies from gastric and duodenal mucosa, appendicectomies, cholecystectomies and colonoscopy biopsies. This study was a retrospective analysis done between January 2015 and December 2017 which included 838 biopsies, both mucosal and resected specimens. These biopsies were fixed in 10% buffered formalin, routinely processed and paraffin embedded sections were taken and stained with Hematoxylin and Eosin. The stains were interpreted and statistical analysis of the data obtained was done. The most common specimen received was appendix which accounted for 49%, followed by cholecystectomies accounting to 38%, 5.5% biopsies from rectum and anal canal, 3%gastric mucosal biopsies, 3% biopsies from colon, 1% mucosal biopsies from small intestine, 0.5% mucosal biopsies from esophagus. In this study it was observed that appendix was the most common specimen received, followed by gall bladder. The most common tumor of esophagus was squamous cell carcinoma. The most common tumor of stomach was adenocarcinoma. Inflammatory lesions were more common in small intestine. Histopathological analysis of gastrointestinal lesions helps the clinicians for proper follow up and specific treatment. This study gives an overview of the various histopathological specimens received in the pathology department.

The paper will outline the basic SWOT and PEST analysis features of the Bayer-AG company from Leverkusen. In this paper, we will present the strengths and opportunities, as well as the weaknesses and threats of the mentioned company. The Bayer AG demonstrates its strength through its strong business relationship and focus on research and development for product improvement. All human resources and financial flow management are well utilized. The paper also deals with the political and technological environment in which the company is located and how it affects the business strategy.

Background: Blood transfusion services play a vital role in the modern healthcare scenario, and blood and its components requirements widely outstrip the supplies therefore a stringent guidelines for transfusion, blood donations and utilization should be laid down and adhered. This study analyses the causes for discard of blood and its components. Materials and Methods: This was a retrospective study of various causes of discard of blood and blood components carried out in blood bank unit of a tertiary care hospital from the data collected from the blood donations by the voluntary donors from January 2014 to May 2017. Results: A total of 3442 blood bags were collected of which 3378 (98.14%) were from male donors and 64 (1.85%) were female donors. majority of the donors were in the age group of 21-30 years (55.37%). a total of 5453 blood /blood components were prepared of which 393 units of blood /blood components were discarded with an overall discard rate of 7.22%. discard rate for WB, PRC, FFP and platelets were 9.22%,4.12%,7.9% and 28% respectively. Conclusion: To prevent wastage of blood a proper coordination should be present between the clinicians and blood bank personnel. An updated software and automation, proper training of staff and a properly implemented blood transfusion policies would go a long way in reducing wastage of this vital body resource

This paper is premised on the findings of a study that sought to find out the challenges faced by Kenyan Interior Designers in relation to their Interior Design Diploma Programmes’ training. The thesis for this paper is that challenges are a reflection of relevant knowledge and skills resulting from having the relevant curriculum and training facilities. As such, acquisition of relevant knowledge and skills by the Kenyan Interior Designers, coupled with the right training facilities and curriculum, leads to minimized challenges thus competences of IDDGs. Consequently, the relevance of the Kenya Interior Design Diploma Programmes to the manpower needs of the industry is therefore enhanced. The study employed a descriptive survey research design and was conducted in Nairobi County, Kenya. 120 Kenyan Interior Design Diploma Graduates formed the study sample. Data was collected using questionnaires, interviews, and observation; analyzed using Statistical Packages for Social Sciences (SPSS version 25) and presented using frequencies. From the study, it was established that KIDDGs face challenges creating detailed drawings from the initial sketches, using CAD, using computer Software applications for 2D & 3D, less team work in construction projects in Kenya between architect and interior designers. Due to inadequate training, majority of KIDDGs cannot deliver given tasks effectively until after retraining. It was also noted that the KIDDGs were looked down upon by architects and other design practitioners during practice making it a challenge to negotiate their salaries. This paper thus calls on the government and the public technical institutions to work towards expanding their contribution of interior design to society through the exchange and development of knowledge and experience in education and practice.