As a communication activity and featuring both cross-language and cross-cultural characteristic, translation transforms the meaning of one language into another. When it comes to translating, it is inevitable to compare features in two different languages. And the research purpose is to find the proper means to translate the culture-loaded words.

Background: Cervical cancer is a preventable disease unlike other cancers. HPV infections have a long incubation period to cause cervical cancer. Other risk factors like early age of conception, illiteracy, low socioeconomic status, use of OCPs for a long period of time, low folate level, high parity and smoking predisposes to cervical cancer. Materials and Method: Present study aimed to identify the risk factors responsible for HPV infections and its association with development of cervical carcinoma in women of age group 20 to 65 years with history of white discharge, blood-stained discharge; heavy menstrual flow, intermenstrual spotting, and postcoital bleeding attending Gynaecology OPD samples of cervical scrapping, Pap smear, Visual Inspection with Acetic Acid (VIA) and Visual Inspection with Lugols Iodine (VILI) was taken for detection for high-risk groups for cervical cancer and its association with different risk factors. Results: HPV infection prevalence in our study was 20% among total of 100 patients. PCR positivity was highest among the age group 30-39 years. HPV infection was highest among the age group 19-20 years. Multiparous women having 3 or more children had shown high positivity for HPV- DNA. Illiterate women and women with only up to primary education had shown the highest HPV infection and it was 18 %. Nonvegetarian women had highest HPV infection. Major symptom of the PCR positive cases was white discharge. PCR for HPV-DNA was 100% positive in women who had cervical growth. Conclusion: Our study shows the importance of Pap smear and HPV-DNA testing of women in our country where prevalence and risk factors are extremely high. It can identify and help in preventing or treating the condition at exceedingly early stage.

The process itself of staging of the disease during pregnancy and the treatment should comply with current standards, to the extent possible. Surgery and/or chemotherapy are considered to be fundamental methods of treatment for invasive cervical cancer during pregnancy. Tactics in the treatment of such patients is determined by a range of factors and depends on gestational age at the time of diagnosis, the stage of the disease, tumor size, as well as on the involvement of regional lymph nodes and the woman’s desire to continue pregnancy. Case Description: A 32 year-old patient, grand multipara, admitted for spontaneous metrorrhagia of low abundance during a 7 month pregnancy (date of last menstrual period is inaccurate) for which she consulted in the private sector where she underwent a gynecological examination that showed a tumoral process of the cervix, and then a biopsy that revealed a cervical squamous cell carcinoma. The patient was then referred to our departement for further care; we decided to perform a C-section at 34 weeks of ammenorrhea, giving birth to a male infant with a birth weight of 2300g, and then a CRC. Conclusion: The incidence of cervical cancer in pregnancy is itself not very high, and the symptoms are easily confused with other diseases in pregnancy. During pregnancy, gynecological examination is limited, and therefore, the rate of misdiagnosis is higher. The treatment of cervical cancer during pregnancy is related to many factors, such as tumor size, pathological type, period of gestation, lymph node involvement, and patients' willingness to maintain pregnancy.

Introduction: The p16 gene is a tumor suppressor gene located at chromosome 9p21, that is a cyclin-dependent kinase inhibitor and is essential in regulating the cell cycle. In human papilloma virus (HPV) infection, the HPV oncogenes E6 and E7 can inactivate pRB and thus lead to p16 overexpression. Materials and Methods: This is prospective and descriptive study conducted in the Department of Pathology, IMS, BHU and HIMS over a period of 1 year from 1st January 2016 to 31st December 2016. Archival, formalin fixed tumour specimens from patients were retrieved from the department of pathology for immunohistochemical staining by means of an anti-p16 monoclonal antibody. In total, there were 90 patients. We evaluated p16 expression for its clinicopathological significance. Result: HPV types and status in correlation with clinical parameters and expression of p16. Eighty five out of 90 patients with primary carcinoma of the vagina (PCV) could be evaluated for HPV status. 26 were positive for high-risk HPV and 59 were HPV negative. The majority (17 out of 26, 65%) of HPV-positive patients were positive for HPV16. The others were positive for HPV45 (4 patients, 16.6%), HPV18 (2 patient, 8.3%), HPV35 (1 patient), HPV56 (1 patient), and HPV68 (1 patient). Human papillomavirus positivity was significantly correlated with strong p16 expression (p= 0.045). In all, 7 out of the 59 HPV-negative patients were negative for p16 immunostaining, while the remaining 83% showed varying expression: 39 out of 59 (60.9%) showed moderate or strong p16 expression. Conclusion: The vast majority of HPV positive vaginal cancers showed p16 overexpression, suggesting active involvement of HPV in the malignant transformation process. More in-depth studies are needed to understand the molecular carcinogenesis pathway in these p16-negative tumors and to improve outcomes for this population.

Thyroid lesions are a common encounter in clinical practice. Standardisation in the reporting of these cases in radiology and cytology is a recent advance. TIRADS system is the standard in the reporting of radiology and Bethesda system (TBSRTC) has been used as the benchmark in cytology. We have undertaken this study with the aim of studying the patterns of thyroid lesions in cytology and compare the same with reporting system in radiology (TIRADS). All the cases coming to the Departments of Endocrinology & Surgery were included and we have 47 cases with a female predominance, 43.7 years was was the mean age of presentation with female predominance, only 2 cases were seen in males. Benign lesions (80%) was predominant over the malignant cases (10%). Most of the cases come under category II in the TBSRTC system in cytology which includes nodular colloid goiter, adenomatous goiter & thyroiditis. Taking the TIRADS system into consideration, most of the cases were included under category 3(probably benign) with the malignancy rate as low as 5%.Maximum concordance was seen between TIRADS 3 and TBSRTC IIresults. Thus our results were in par with other similar studies. Fine needle aspiration can thus be performed only in cases which belong to TIRADS IV or V and thus avoid unnecesary aspirations.

Thyroid diffuse large B cell lymphoma (DLBCL) presents typically as a rapidly growing neck mass that is sometimes accompanied by respiratory compression symptoms. It is more predominant in women and has a peak onset age of 50 to 70 years [1]. DLBCL should be treated with chemotherapy and radiotherapy after diagnosis through biopsy, and extensive surgery should be avoided. Here we describe a rare case of 63-year-old woman who was admitted in our ENT department due to rapidly growing (2 months), painful thyroid enlargement with compressive cervical symptoms.

This study aims to determine the integrity of the financial statements of plantation companies listed on the Indonesia Stock Exchange 2017-2020. This study began to observe information on cases of disclosure of corporate financial statements that are published and do not meet the characteristics of accounting standards in several business sectors which are thought to be influenced by various factors such as managerial ownership, profitability ratios, and company size. This study used quantitative methods with multiple regression analysis through statistical data analysis software SPSS. The data used is secondary data which is collected through literature review and downloading the issuer's financial statements via IDX.co.id. This study found a negative effect of managerial ownership and firm size on the integrity of financial statements, while the effect of profitability was not found. This finding explains the function of managers as agents and at the same time as a principle of providing great opportunities for managers in making policies that benefit themselves so that the integrity of financial reports is low, as well as the fact that the level of company prosperity encourages management to take policies that have an impact on low financial statement’s integrity.

This report validates the anti-hyperlipidemic property of Pleurotus tuber reguim an edible mushroom widely used for weight loss among other ailments, using Triton X-100 induced hyperlipidemic rats. The lipophilic chloroform (CHE) and hydrophilic 70 % aqueous ethanol (AQE) extracts were obtained by successive cold maceration in increasing order of solvent polarity. Anti-hyperlipidemic activities of the extracts at 100 and 200 mg/kg body weight, was evaluated using Triton X-100 induced hyperlipidemic rats. Artovastatin was used as the standard drug. Compared to the hyperlipidemic untreated control group, there was a significant (p<0.05) dose dependent reduction in the plasma total cholesterol (TC), triglyceride (TG), very low density lipoprotein (VLDL), low density lipoprotein (LDL), and increase in the high density lipoprotein (HDL) after 7 days treatment with the extracts. The trend in the ameliorative activities of the extracts and atovastatin were in the following rank order: atovastatin (43.5%)>CHE-200mg/kgbw (41.4%)>CHE-100mg/kgbw(38.4%>AQE-200 mg/kgbw (35.9%)>AQE-100 mg/kgbw (27.6%) for TC; atovastatin (73.5%)>CHE-200mg/kgbw (68.0%)>CHE-100mg/kgbw(64.5%>AQE-200 mg/kgbw (62.3%)>AQE-100 mg/kgbw (62.2%) for TG; CHE-200mg/kgbw (114.4 %)> AQE-200mg/kgbw(87.3%) >atovastatin (68.7%)>CHE-100mg/kgbw (38.5%)>AQE-100mg/kgbw(8.8%) for HDL; atovastatin (73.5%)>CHE-200mg/kgbw (68.0%)>CHE-100mg/kgbw(64.5%>AQE-200 mg/kgbw (62.3%)>AQE-100 mg/kgbw (62.2%) for VLDL; and CHE-200mg/kgbw (78.5%) > atovastatin (66.8%)>AQE-200mg/kgbw (63.5%)>AQE-100mg/kgbw(26.8%) for LDL. Triterpenoids (phytosteroids), fatty acids, and cardenolides are present in the CHE while, amino acids, saponins and carbohydrate were present in the AQE as metabolites with alkaloids and anthraquinones were absent. P tuber reguim possesses anti-hyperlipidemic effects which could be due to the phyto-constituents present thus justifying its traditional use for weight loss.

This study aims to determine the effect of current earnings, operating cash flow and accrual quality on future earnings. The population of this research is manufacturing companies listed on the Indonesia Stock Exchange for the period 2016-2018. The sample used purposive sampling and obtained a sample of 100 companies with a time period of 3 years to obtain 300. Earnings are proxied by net earnings after tax which is scaled to total assets or Return on Asset, Accrual quality is proxied by discretionary accruals of working capital, Future earnings are earnings. In the period t+1. The research method concludes that there is a positive and significant effect of current earnings and operating cash flows on future earnings, while accrual quality has no effect on future earnings.

Background: Surgical cancellations at the day of surgery present major difficulties to both health care organizations as well patients and families. In a low middle income country (LMIC), cancellations stress an already resource limited system and result in significant financial burden and loss of resources. Due to a limited number of tertiary care hospitals, most families have to travel great distances and outpatient visits for preoperative assessment are unfeasible. We describe a protocol using screening phone calls and patient’s family counseling prior to admission to reduce same-day cancellations rates. Objective: To determine whether implementation of nurse –led protocol involving screening phone call and standardized questionnaire, along with patient’s family counseling 48 hours prior to surgery results in reducing day-of-surgery cancellations. Methods and measures: Pre-intervention data to calculate rate of cancellations was collected. Patient’s families were called 48 hours prior to surgery. A standard assessment checklist was used to cover pertinent points. A brief counseling session was also carried out regarding the surgery .In case of any concerns, attending surgeon and cardiologist were informed and a follow up call made on the day before surgery. A satisfaction survey regarding the effectiveness of the phone call was carried out after discharge from the hospital. Post intervention data was then collected and cancellation rate calculated. Results: Post-intervention, data from 144 screened patients was collected. Day of surgery cancellation rate decreased from 15.2% to 1.43 %( p<0.05) (fig 3). An average cost of $540 (Pakistan Rupee 80000) was saved per cancellation. Most families reported overall satisfaction with the phone call. Conclusion: Implementation of standardized protocol for preoperative assessment has decreased day of surgery cancellations, resulting in better resource utilization and reducing overall hospital costs. It has also helped in improving communication between patient’s family and heath care providers and improved overall patient satisfaction.

Education is undeniably a potent tool for facilitating latent knowledge and development of skills. But more importantly, education has come to play a significant part in cultural re-orientation and social engineering. In this era of cultural integration and environment sensitization, education (and even more so environmental education) has come to play a central role in determining individual and group cultures (locally and internationally) and in their modification are they relate to the environment. These are the issues highlighted in this paper which examines the imperatives of environmental education for sustainable development in a constantly degrading environment.

We attempt to understand the cross-country impact of interest rate on macroeconomic economic activities among a few major economies such as advanced economies (US, Japan, and Germany) and emerging economies (China, India, and Russia). Using Generalized Impulse Response analysis of VAR model, we find that advanced countries' interest rate affects economic activities relatively higher than emerging economies' interest rate. Contrastingly, among emerging economies, China's interest rate influences economic activities of all while interest rates of India and Russia have either marginal or no impact on others' aggregate economic activities, including advanced countries.

Rhabdomyosarcoma is a malignant mesenchymal tumor with striated muscle differentiation. Most commonly developing in children or adolescents. Previously three subtypes have been described: embryonic, alveolar and pleomorphic. Spindle cell / sclerosing rhabdomyosarcoma is a rare new subtype described in the latest edition of the WHO soft tissue, it develops in children and adults and it is subdivided into 3 genomic groups with different prognosis according to the latest advances in cytogenetics. We report a case of sclerosing rhabdomyosarcoma in a 15-year-old boy with painful swelling of the forearm that has progressed for 3 months. Microscopic examination shows entirely tumor fragments, consisting of an eosinophilic hyaline matrix delimiting tumor lobules and nests, sometimes with a pseudo-vascular and alveolar appearance. Tumor cells have small, irregular and hyperchromatic nuclei with coarse chromatin and eosinophilic cytoplasm. Rare rhabdomyoblast cells are noted. Immunohistochemistry shows expression of Desmine; Myogenin; CD99; Myo D1 and loss of SMA expression.

This research purpose to further investigate the role of Investment Policy, Organizational Strategy and Company Performance towards Corporate Social Responsibility. This research took 21 companies on manufacturing sector that still active on the IDX during 2014-2016 as research studied. This research were validate the hypothesis which stated that Investment Policy, Organizational Strategy and Company Performance had a partially or wholly affects the Corporate Social Responsibility. Through multiple regression analysis, it was found that the Investment Policy and Company Performance statistically had a positive impact substantially on Corporate Social Responsibility, but not to Organizational Strategy which did not have a substantial impact on Corporate Social Responsibility. Thus, Investment Policy and Company Performance served as the main determinants of corporate social responsibility disclosure in the manufacturing sector in Indonesia.

Knowing the impact of the auditor's competence, work experience, and internal control on audit quality is a goal to be achieved. This type of research uses quantitative research with saturated samples. The data collection technique is primary data that comes from questionnaires, then secondary data is taken from company documentation. The population in this research was 32 internal auditors as respondents at PT Bank Rakyat Indonesia (BRI) Tbk, which is headquartered in Jakarta in the Internal Audit Unit (SKAI). The data analysis technique used SEM with Smart PLS software for windows version 3.0. The results of this research show that audit quality is significantly affected by auditor’s internal control, while competence and work experience have no significant effect.