Ovarian pregnancy is a rare entity among ectopic pregnancies where the ovary is the site of implantation. Its diagnosis requires a well codified approach. The particularities of the determining factors, histopathological and evolutionary characteristics of ovarian pregnancies led us to take an interest in this form of ectopic pregnancy. We report a case of ovarian pregnancy treated during our shift. It concerns a 42 year old woman, multiparous, with a notion of delay of menstruation of 3 weeks. She presented to the gynecological emergency room with acute pelvic pain complicated by shock. On examination, the diagnosis of ampullary ectopic pregnancy was made. The patient was resuscitated and underwent emergency surgery. The diagnosis of ovarian pregnancy was made intraoperatively, for which a salpingectomy was performed. The postoperative course was simple. Indeed, the diagnosis of ovarian pregnancy is difficult and is based on intraoperative findings. The presence of the ovarian nidation zone on histopathological examination is optimal to confirm the diagnosis. Treatment is based on surgery with the development of conservative techniques by laparoscopy when the patient's hemodynamic state allows it.

Staphylococcus aureus is a common hospital and community-acquired pathogen known to be frequently associated with wound infections. Therefore, the aim of the research was to determine the incidence of Staphylococcus aureus in patients with wound infection at University of Port Harcourt Teaching Hospital, Rivers State, Nigeria. A total of 150 specimens from different types of wounds (traumatic wound, caesarean section, scrotal wound, surgical wounds, burns, diabetic foot, and plastic surgery) were collected from the Hospital for a period of six months and processed for isolation of S. aureus, following standard microbiological procedures. Samples were cultured on sterile mannitol salt agar (MSA) plates and characterized phenotypically based on cultural and biochemical identities. Data obtained showed 38.7% of the wound cases were contaminated with Staphylococcus aureus isolates. It was observed that the organism mainly occurred in burns (52.63%), while the lowest incidence was related to plastic surgery (18.2%) contamination. The study showed that 10.3% of isolates were associated with biofilm formation, while gamma hemolysis and beta-hemolysis was observed in 93.1% and 6.9% of isolates, respectively. The results of this study represent serious public health concerns, thus emphasizing the need for proper wound management.

The main purpose of this study was to examine the challenges facing visually impaired pupils on academic achievement in special needs primary schools in Bukoba District, Tanzania. The study was guided by a specific objective: to examine visual impairment challenges facing special needs pupils’ academic achievement in Bukoba District. The study was anchored on Maslow’s theory of needs. The study employed a survey research design. The target population was 791 respondents that involved 53 teachers, 735 visually impaired pupils, 2 Head teachers, and 1 DEO. The sample size was 39 teachers, 47 visually impaired pupils, 2 Head of schools and 1 District Educational Officer. The researcher used questionnaires and interviews guides as the tools for research data collection. The study found 92.3 percent agreed by saying that there were some challenges facing visually impaired pupils on academic achievement while few respondents equal to 7.7 percent respondents responded by saying there are no challenges facing visually impaired pupils in special needs primary schools in Bukoba district. Finally, the study recommends that the government should put much effort on supporting visually impaired pupils through financial support as well as allowing more teachers to go for further training, besides providing relevant teaching and learning resources. Ethical considerations were adhered to including seeking consent of the respondents and guarding against plagiarism.

We analyse the acceleration of integrated public transportation management in DKI Jakarta. Here we focus on the case of Bus Rapid Transit (BRT) or called TransJakarta. In this study the qualitative research methods are used through post-positivism paradigm. We collect the data through observation, interviews, and literature studies. We found that the acceleration of BRT-based integrated public transportation management in DKI Jakarta can be well carried out if each stakeholder understands and implements the transportation management system that has been approved whether it is for planning, organizing, or supervising. Meanwhile, there are several components that are needed for accelerating BRT-based integrated public transportation management: route restructuring, transportation integration, single bus operators, and fair law enforcement. It is also important to realize the collaboration among Indonesian regional-own enterprises (BUMD), Indonesian state-own-enterprises (BUMN), and all stakeholders for creating sustainable and equitable bus-based public transportation in DKI Jakarta.

Swine influenza strain can be transmitted from human to human and causes normal symptoms of influenza. Transmission mainly occurs between pigs and pigs and humans. Our present study is of a 72yrs old male who died of H1N1 infection. Postmortem findings showed congested and edematous lungs with patchy areas of consolidation. Histopathological findings in lung revealed edema, pneumonic changes, hyaline membrane formation and focal cytophagocytosis.

Developing wound infection in type Ⅰ or Ⅱ diabetic people had risk complications like gangrene. Although there are enough antibiotic ointments or creams, still it needs physician dressing and continuous monitoring of wound. So, to make it simple and more effective, a combination of transdermal drug delivery route with herbal usage contribute in controlled release of medication with minimum undesirable side effects. And also help to treat wound infections by self-medication. This work is focused, to formulate wound healing transdermal patch for diabetics with Momordica cymbalaria tuber extract. A sequence of techniques was performed to analyse antioxidant content then Starch assay was performed In vitro to evaluate its healing efficacy, determine cytotoxicity using zebra fish embryos and artemia salina using hexane extract of tuber. Optimized combination is used to prepare Patch by solvent evaporation method then evaluated the patch by organoleptic and physico-chemical properties. The result proofs, the tuber extract had Strong Antioxidant activity whereas weak cytotoxicity showed in two concentration (25 and 50µg/ml) towards brine shrimp lethality assay and fish embryo toxicity. High migration rate found in 25µg/ml and 50µg/ml in scratch assay using Human Epidermal Keratinocytes. Evaluated the patch for its organoleptic and physico-chemical properties, it shows good result. As a final observation of the study, bio compounds present in tuber extract proved to enhance wound healing and could pave way as alternate to the synthetic wound healing patches owing to its ecofriendly, economical and herbal nature be natural replacement to hasten wound healing especially in diabetic patients.

Instructive approaches for testing emerging malaria vaccine candidates could potentially have a lot of translational value. The potential of genetically altered Plasmodium species that do not grow beyond the liver stages, in triggering a protective immunity. Giardia-lamblia, Ascaris-lumbricoides, Trichuris-trichiura, Schistosoma species and Entamoeba-histolytica are most intestinal worm parasites around worldwide. Amebiasis is caused by Entamoeba histolytica invading the intestinal mucosa and causing severe mortality and morbidity. Babesiosis is tick borne infectious disease which causes anaemia, fever, haemoglobinuria, and frailty in the animals. Various bacterial species have been found in fish’s natural habitats. Bacterial colonies can be seen on fish’s gills and skin as a result of persistent contact to unclean water, whereas polluted water or food might harm the gastrointestinal tract. Salmonella nontyphoidalis is the most common zoonotic bacterial food borne infection in humans. Salmonellae are common around the world, and they are the most common pathogenic bacteria in both humans and animals. Engineering the genes which code for pathogenicity effectors and host adaptability could be the key to completely identifying the causal relationship among a gene deficiency and infections in organoids.

In this research article, Cobalt nanoparticles were green synthesized, Characterized and applied in antimicrobial study of some selected pathogens. The formation of cobalt nanoparticles was confirmed by first, its colour change from light brown to dark brown within 10 minutes. From the UV-Vis spectral analysis, it was observed that highest absorption peak appeared at 400nm reflecting the surface Plasmon resonance of Cobalt NPs from Parkia biglobosa stem which is characteristic of Cobalt Nanoparticles. From the FT-IR studies, the absorption peaks were seen at 3787.71 cm-1, 3660.31 cm-1, 3436.44 cm-1, 1638.75 cm-1, 1384.50 cm-1, 1090.80 cm-1and 798 cm-1. Investigation revealed a medium sharp peak absorption at 1090.80 cm-1which may be attributed to the stretching of aliphatic hydrocarbon (C–H). A peak at 1384.50 cm-1corresponds to C=C stretching while the absorption bands at 1638.75 cm-1and 3436.44 cm-1may be assigned to N-H and O-H stretching vibration modes respectively. Similarly, peaks were seen at 3787.71 cm-1 and 3660.31 cm-1 corresponding to O-H belonging to water and alcohol respectively. Furthermore, the very strong band at 798 cm-1emanates from C-O-C symmetric stretching and C-O-H bending vibrations of protein in the Cobalt nanoparticles. The surface morphology of the bio fabricated Cobalt nanoparticles, has revealed by SEM image, is spherical in shape having smooth surface and well dispersed with close compact arrangement. From the microbial study carried out, the surfaces of the cobalt nanoparticles might have interacted directly with the bacterial outer membrane, causing the membrane to rupture thereby killing the microbes. The antibacterial activity demonstrated by the cobalt nanoparticles in this study could be attributed to their small size and high surface to volume ratio, which therefore enables them to interact closely with bacterial membranes. From the minimum inhibitory concentration (MIC) study conducted, it showed clearly that the green synthesized cobalt nanoparticles inhibited the growth of the pathogens investigated.

A nano-metallic drug called Bhasma is created from metal and minerals. It has long been regarded in Ayurveda as a trustworthy and quick-acting dose type. The following procedures—Shodhana, Bhavana, Mardana, and Marana—are used to prepare Bhasma. These processes assist in breaking down particles into their smallest components, get rid of undesirable traits, and give the substance new properties that make them more palatable to the body's tissues and organs. In the classic, various Bhasma Parikshas, such as Varitaratwa, Unnama, Rekha purnatwa, Nirutha, and Apunarbhava, are mentioned. However, these tests are insufficient to determine the safety and efficacy of Bhasma. For the examination of Bhasma, various contemporary factors are used to ensure its acceptance on a global scale like physical evaluation, chemical analysis, and instrumental analysis. Bhasma efficiency is reliant on its homogenous chemical composition, nanocrystalline structure, and biological activity. These highly sophisticated analytical tools, including XRD, SEM, TEM, NTA, ICP-MS, XRF, AAS, and FTIR, are required for the detection of crystal size, particle size, shape, surface area, dispersion state, and morphological features, in addition to chemical and physical properties like reactivity, optical behaviour, magnetism, zeta potential, and others. To understand the toxicity, pharmacokinetics, and pharmacodynamics of Bhasma, all of these methods are employed. As a result, the current paper's main focus is on characterizing Bhasma using modern sophisticated instrumental techniques.

Rasa Shastra and Bhaishajya Kalpana has evolved as a separate branch of Ayurveda, where different formulations prepared using different dravyas can be used for curing different diseases. This is called as Formulation Development. These formulations are prepared on the basis of Disease, Dose, and mainly Rasa Panchaka. While formulating different medicines, Acharyas have framed the dravyas in such a way that the end product will be having the same properties of the drug and its action which it is intended to perform. One such formulation is Hinguleshwara rasa quoted in Rasa tarangini, Vishopavishadivignyaneeya. The medicine is prepared in such a way that, half ratti i.e., 62.5mg dose is enough for curing Vataja Jwara and Ama Vata. The aim of this present article is to focus on its probable mode of action in reference to Jwara, which can be assessed on the basis of Rasa Panchaka of the drugs individually.

Background: Methotrexate helps your immune system from assaulting your body's cells by calming it down. This helps to lessen the inflammation that causes rheumatoid arthritis's swollen and stiff joints, psoriasis' thickened skin, and Crohn's disease's gut damage. Because of its powerful effectiveness and safety, In the treatment of rheumatoid arthritis, methotrexate (MTX) is used as an anchor disease-modifying anti-rheumatic drug (DMARD) (RA).Although MTX aids a huge percentage of RA patients, it is not without adverse effects. When treating rheumatoid arthritis patients with the MTX, wide a variety of adverse effects, from minor to severe, can occur, leading to therapy termination. One putative harmful effect of methotrexate on the due to a local folate deficiency, there is a reduction in hepatic folate stores and toxicity. When MTX used with other medications, further research is needed to improve efficacy while reducing adverse effects. The management of MTX therapy is also reviewed, as well as options for dealing with adverse effects that may arise. Objective: The purpose of this study was to see how methotrexate affected individuals after 6 to 12 months of treatment for rheumatoid arthritis. Methods: Data was collected at the Shalamar hospital, Pakistan, between January 2021 and June 2022. Non-Probability Purposive Sample is the sampling strategy used in this investigation. Following the assignment of a study subject, the research took around 6 months to complete. After giving their informed consent, 120 patients between the ages of 30 and 50 were involved in this study. Data will be acquired using data collection technologies when an informed written permission form has been completed. Result: In this study 120 Rheumatoid Arthritis patients were studied, with 64 males (53.3%) and 56 women (46.7%) having an average age of 40 to 45 years and a range of 30 to 50 years. took part in the study, as shown in the graph (Table 3). In this study, 4 patients are 30 to 35 years old and have a percentage of (3.3%), 18 patients are 36 to 40 years old and have a percentage of (15%), another age group is 41 to 45 years old and has a percentage of (47.5%), and the last age group is 46 to 50 years old and has a percentage of (34.2%), as shown in the table (Table 2). The (Table 5) indicates the usual range of LFTs before Methotrexate, which is completely normal with no fluctuation in LFT parameters. As demonstrated in (Tables 6 and 8) where we examine the before and after effects of Methotrexate on the basis of patient immunity in 79 patients, the values of LFTs alter and become higher in comparison to normal, with a percentage of (65.8%). We compare the impact of Methotrexate on the basis of Gender using cross tabulation, which shows that LFTs were high in 41 males (67.1%) and 38 females (64.9%), as indicated in (Table 10). Finally, we compare the effect of Methotrexate on the basis of age factor as shown in (Table 11). After MTX therapy, RA patients experienced gastrointestinal side effects such as nausea, vomiting, and diarrhea, implying that MTX therapy will definitely affect the LFTs level and, most likely, according to the current study, will raise the LFTs level in blood, which will be treated promptly before further serious complications arise. A timely follow-up will be advised to all patients with consistently high LFTs levels. Conclusion: In this study, we discussed rheumatoid arthritis and the effects of methotrexate on rheumatoid arthritis patients' lives. It would appear that methotrexate is gaining popularity in the treatment of rheumatoid arthritis. Although there is risk of infection & probable cancer, the hazards are much outweighed by the potential therapeutic benefits. We also talked about R.A. diagnostic procedures. We covered the many characteristics of this autoimmune condition as well as several diagnostic approaches in this study.

The study aims at: Preparing exercises using (S.A.Q) method and its impact on developing some physical fitness and skills abilities for youth handball players. Identifying the effect of (S.A.Q) exercises in developing some physical fitness abilities for youth handball players. It is hypothesized that: There are statistically significant differences between the two groups (experimental and control) for the pre and posttests in the development of some physical fitness and skill abilities for youth handball players. There are statistically significant differences between the two groups (experimental and control) for the post-test in the development of some physical fitness and skill abilities for youth handball players. The researchers have used the experimental method by designing the experimental and control groups with pre and post tests for its suitability and the nature of the current research problem. The research community is represented by the youth players of Salah El-Din Handball Club for the sports season 2020/2021 numbering to (22) players. A number of (4) players are excluded as follows (2) goalkeepers and (2) players, due to their participation in the pilot experiment. So, the number of sample members is (18) players constituting (81.8%) of the research community. Conclusions: The (S.A.Q) exercises have brought about a development in the studied fitness variables of quickness and agility. The exercises used have led to a development in the level of the offensive side, especially the skill of shooting, whether from the remote areas or those close to the goal.

As the allocated forestland for pulp and paper production in Bangladesh is very limited and a substantial amount of crops residues are generated each year, the latter can substitute for pulp and paper production. In this context, eight residues of crops produced in Bangladesh were evaluated. Final pulp yields were 40 -65% with the kappa number of 11-32% depending on crops residues. The experimental processes are outlined. The physico-mechanical properties of handmade papers are estimated by standard procedure. Gram per Square Metre (GSM), brightness percentage, thickness and tearing strength of different handmade paper sheets shows acceptable papermaking properties. FT-IR analysis were carried out for identifying types of chemicals bonds (functional groups).The study indicates that these hand-made papers can be used for making eco-friendly paper bags, packaging material which will be suitable alternative to the non-biodegradable plastic, a cause of ecological and environmental pollution.

Jute is highly flammable in character. Due to its high degree of flammability, the versatile use of this fibre is handicapped to some extent, particularly in some specific purpose where jute products with flame resistance finishes and demanded. Considering this disadvantage, a research project was undertaken to make this fibre flameproof and therefore safer in specialized textile uses. The study was performed using yarn and fabrics which were desized with diastase and lissapol-N. Yarn and fabrics were scoured with sodium carbonate, sodium hydroxide under some standard conditions. These pretreated yarns and fabrics were used in the whole experimental work. The treated yarns were tested for flame retardant by subjecting them to the luminous flame of Bunsen burner and by observing the time of flaming (after flame) and time of glowing (flameless combustion, after glow), if any Percentage losses of strength of the treated yarn and fabrics were also measured by standard method. Different solutions of fire resistant chemicals were prepared to change the chemical, concentration and pH ratio of the solution. Jute fabrics and yarns treated with 65% solution of urea and ammonium dihydrogen phosphate (the ratio of urea and ADP being 3:2) together with 2% Turpex NP and 3-6% perapret PE-40% were found durably flame retardant causing minimum loss of the strength. This research was focused on fire resistant treatment of jute yarn and fabrics with different chemicals to make jute products for diversified textile uses.

This work is an attempt to understand the effect of climate in an environment, therefore the effect of driving rain on buildings and on monuments is considered a case study. The study area is Port Harcourt Metropolis, a subequatorial climate environment, located in southern part of Nigeria. The study made use of questionnaire, and response were analyse using a descriptive statistical tool (simple percentage and pie chart). The study observed among other things that driving rain defaces buildings and monuments. Furthermore majority of those interviewed are of the opinion that driving rain has made them spend more money in building and monument maintenance as the case may be. It was also observed that driving rain contributes to rill erosion within and around buildings and monuments. The study also finds out that driving rain affects the strength of buildings negatively, and that electrical appliance can also be affected. This work suggests among other things, that water resistance paints and material should be used on buildings and monuments. The windward side of buildings should be designed in a way that the effect of driving rain should be minimal on the wall or windows. Furthermore, materials like books, cloths and other weather sensitive materials should be kept away from the damp windward side of the rooms. This implies that wardrobes should not be fixed or constructed in the windward side of the building. The study suggested that strong materials and standard specification of concrete mixture and standard original materials should be used in building construction especially in a humid environment like Port Harcourt metropolis. Finally, geographical factors need to be considered before building construction and professionals should be engaged in the business of building of houses and monuments construction to avoid collapse and damages.