Anaemia is a public health problem that affect both the rich and poor, and it possess a serious challenge to the health care profession, consequently this research is therefore aim at investigating the anti - anaemic potentials of Tigernut (C. esculentus) extract administered to albino wistar rats exposed to Phenylhydrazine induced toxicity. Forty (40) male albino Wistar rats weighing between 180- 250g were used for this study. They were randomly divided into four (4) groups of ten (10) rats each. Control group received normal feed and drinking water. Extract group received 600mg/kg bw of aqueous extract of Tigernut orally, PHZ group received PHZ induction and PHZ + Extract group received PHZ induction + 600mg/kg bw of aqueous extract of Tigernut. The feeding regimens lasted for 4 weeks, after which blood samples were collected via cardiac puncture for estimation of different parameters. Results showed that ingestion of aqueous extract of C. esculentus was able to reverse the significant decrease in RBC (p<0.01), HB (p<0.001), PCV (p<0.001) and Fe+ (p<0.01) values occasion by PHZ induction, back to appreciable level. In conclusion ingestion of C. esculentus extract is capable of reversing the derogatory effect imposed on hemopoietic processes following PHZ induction. Since C. esculentus is cheap and readily available it can therefore be recommended for the management of anaemic condition pending the availability of a viable health facility.

The objectives of this research are to analyze and find legal weaknesses in the settlement of traffic accident cases using a restorative justice approach and how to reconstruct the legal settlement of traffic accident cases with a restorative justice approach. The method used in this study uses an empirical approach and a normative juridical approach with the paradigm used by the constructivism paradigm. The results of the research show that the Weakness of the law in the settlement of traffic accident cases is in the lack of integration of legal arrangements for the settlement of criminal cases in the criminal law system, especially in the Criminal Procedure Code according to the rules of each institution. As a result, arrangements for settling cases based on restorative justice have not been able to guarantee legal certainty Therefore the legal reconstruction of the settlement of traffic accident cases with a restorative justice approach proposed by the author can be done by revising the provisions of Article 230 and Article 235 of Law no. 22/2009 concerning LLAJ, so that light, moderate and severe traffic accident cases can be resolved based on restorative justice. In addition to this, for heavy traffic accidents that cause fatalities, the settlement of cases based on restorative justice must not abort the prosecution of cases as it involves fatalities and therefore it must be processed normally.

The background of this research is what are the weaknesses of the application of restorative justice in cases of medical disputes and how to reconstruct the law based on Restorative Justice value as a means to find new legal breakthroughs that are useful for the medical world as well as fulfill aspects of victim protection. The method used is an empirical approach, namely Sociological Normative, in which the study used in this research is a Socio-legal research approach. The findings of this study show that the weaknesses of the application of restorative justice in cases of medical disputes settlement is that the handling of cases of suspected medical disputes by police investigators will of course use procedures or procedures that are it is in the Criminal Procedure Code as a reference, this is because the UUPK and the Health Law do not regulate how the proceedings should be carried out if there is an allegation that a doctor has violated the articles in the UUPK as Mediation has weaknesses, namely limited juridical support for the process and its results, including the execution of the resulting dispute settlement (peace) agreement. The process and the resulting decisions cannot simply be forced. Laws that regulate mediation have not yet been enacted to provide legal certainty, so it is necessary to carry out legal reconstruction in the Law on Health and the Law on Medical Practice.

The objectives of this research are to analyze and find legal weaknesses of Victim's Protection Regulations through Claims for Damages Case Combination and how to reconstruct the Victim's Protection Regulations through Claims for Damages Case Combination based on justice value. The method used in this study uses an empirical approach and a normative juridical approach with the paradigm used by the constructivism paradigm. This study uses the constructivism paradigm. The approach method used is sociological juridical, with descriptive-analytical research specifications. The data used are primary data and secondary data, which are then analyzed. The results of the study show that the weaknesses in merging cases for compensation claims include: a) Lawsuits can only be filed at the first level; b) The public prosecutor who enters the request for compensation in the case file; c) The decision on compensation demands is very dependent on the criminal case, therefore, Based on the foregoing, the legal reconstruction as intended by the author is by adding a new article, namely article 98 paragraph (3) which reads: "That the Public Prosecutor is obliged to ask the victim whether he wants to make a claim for compensation" and also revises Article 100 paragraph ( 2) so that it reads: "If a criminal case is not filed for an appeal, then an appeal regarding the decision for compensation is still permitted."

The objectives of this study are to analyze and find weaknesses in the Regional Notary Assembly Supervisor Authority in Indonesia currently and how to reconstruct the law to realize a better Regional Notary Assembly Supervisor Authority based on justice value. The method used in this study uses an empirical juridical approach supported by a normative approach with the paradigm used by the constructivism paradigm. The results of the research show that there are that the regulation of the authority of the notary regional supervisory board in the context of supervising notaries is currently not optimal based on the value of justice as there are weaknesses in the regulation of the authority of the notary regional supervisory board in the framework of supervising notaries at this time as the board don't have the authority to impose sanctions on a notary. Therefore, there is a need for reconstruction of the authority of the regional notary supervisory board as stated in article 70 of Law No. 30 of 2004 concerning the position of a notary, in which the notary regional supervisory board must have the authority to impose sanctions on a notary.

The purpose of this study is to analyze and find the weaknesses of agrarian reform in the implementation of land acquisition for development that has not been fair and how to reconstruct the law based on the value of justice. This study uses a constructivist paradigm with a sociological juridical approach to solving research problems by examining secondary data and primary data by finding legal realities experienced in the field as well as qualitative descriptive methods, namely where the data obtained is then arranged systematically so that a comprehensive picture will be obtained, where later the data will be presented descriptively. Based on the research results, it was found that the Weaknesses of agrarian reform in the implementation of land acquisition for development have not been fair, namely in terms of legal structure where there is overlapping issuance of a decision from agencies directly related to land and agrarian reform. in terms of legal substance Amendments to Law no. 2 of 2012 concerning Land Acquisition for Public Interest which is regulated in the Job Creation Law and Government Regulation no. 19 of 2021 concerning the Implementation of Land Procurement for Public Interest, has made agrarian conflicts escalate. The three aspects of legal culture namely the presence of a national strategic project in an area create conflict between communities in their respective interests. Therefore, the legal reconstruction of agrarian reform in the implementation of land acquisition for development based on the value of justice intended by the author is in the Part Three of Protection of Sustainable Food Agricultural Land Article 124 paragraph (2) In the case of public interest, Sustainable Food Agricultural Land as referred to in paragraph (1) can be converted, and implemented in accordance with the provisions of laws and regulations.

Background: The challenges in healthcare continuously evolve. Patient flow, on time coordination of right care and at the same time utilization of hospital resources are all equally important to manage day to day scenarios in a hospital. Purpose: The purpose of this phenomenological study is to explore the perception of Emergency Department (ED) nursing staff about the implementation of the Urgent Care Clinic (UCC). Methods: The Phenomenological-Transcendental approach was conducted in the ED of Security Forces Hospital, Riyadh, Saudi Arabia. The target study population were ED nurses. The purposive sampling technique was used to select 15 samples, who underwent interviews. The inclusion criteria for the participants included full- time Registered Nurses with more than 1 year of experience in the ED, having a diploma or a degree in nursing and participation willingness. Exclusion criteria included newly registered nurses or those nurses holding senior management positions. Results: The interview tapes were transcribed verbatim by a transcriptionist who was knowledgeable with research data confidentiality. Colaizzi's (1978) seven stages of phenomenological technique was used to analyze the data and refine emergent information into themes. Conclusion: This research explored the perception of the ED nursing staff about the implementation of the UCC utilizing Colaizzi's process of phenomenological data analysis to achieve the description of lived experience of the ED nurses.

Nursing research has become increasingly important in health care environment. This paper explores the barriers to research among nurses at the Ministry of National Guard-Health Affairs in Saudi Arabia. This cross-sectional quantitative study was conducted between November and December 2020. The study has utilized a questionnaire comprising of demographic data and a set of perceived barriers categorized into groups, i.e. nurse, institutional and educational barriers. 482 questionnaires were analyzed. The strongest barrier in the nurse category was not knowing how to get involved at 43.1% (n=208; Agree), not having access to mentors with research experience, 45% (n=217; Agree) in the institutional category, and lack of training in research, 46.7% (n=225; Agree) in the educational preparation category. The study showed that multiple factors contributed to lack of engagement in research among this nursing cohort. Therefore, any interventions require a systematic and multiple-pronged approach to support nursing research.

The aim of this research is to find and analyze the weaknesses of the judge's decision on the obscure lawsuit exception in Indonesia and how to reconstruct it based on justice value. This study uses the constructivism paradigm, the approach method is sociological research, the research specifications are analytical descriptive, the data used are primary data and secondary data, primary data is obtained by interview while secondary data is obtained by means of literature study, data analyzed qualitatively by using the Dignified Justice Theory, Legal System Theory, and Progressive Legal Theory. The results of the study show that the Weaknesses include weaknesses in legal substance, namely weaknesses in the provisions of Article 136 HIR. Weaknesses in Legal Culture are that positivism is still the mainstream of judges therefore the Panel of Judges often does not read and study cases together from the start and the Chairperson of the Panel of Judges as a senior judge is still decisive in making decisions, next, the weaknesses in the Legal Structure including the acceptance stage, where, after starting their career as a judge, they must submit themselves to the supervision of judges and structures outside the court. Therefore, the legal Reconstruction intended by the author is related to the values of Pancasila, as the Reconstruction of the Norm is an exception to the obscure lawsuit being considered and decided before the examination of the main case.

The objectives of this research are to analyze and find out the weaknesses in the legal construction of the authority to implement Deponering (the authority of the attorney general not to prosecute a case for policy reasons) in relation to the principle of opportunity by the prosecutor's office and how to reconstruct the law based on justice value. The method used in this study uses an empirical approach and a normative juridical approach with the paradigm used by the constructivism paradigm. The results of the research show that the Weaknesses in the legal construction of the implementation of Deponaring by the Attorney General in relation to the application of the opportunity principle, one of which, is the basis for consideration of the public interest which does not yet have clear and measurable indicators. In addition, minimal supervision of the implementation of the Attorney General's authority. In order to tackle this, a legal reconstruction of the authority to implement Deponaring in relation to the principle of opportunity based on the value of justice is needed to determine the indicators and conditions for the Attorney General in making decisions overriding cases in Government Regulations, so that the implementation of the Attorney General's sole authority does not escape supervision and fulfills justice for society. As a counterweight to Deponering authority, the public prosecutor must be given the authority to stop prosecution based on restorative justice which is based on the discretionary authority of the Attorney General's Office as a response to the development of society that wants misdemeanor crimes and crimes with low economic value not to be continued with the prosecution process, by prioritizing the principle of restorative justice. Termination of prosecution based on restorative justice by the public prosecutor, which in practice is very beneficial for the wider community, especially for victims and perpetrators of crimes.

The objectives of this study are to analyze and find weaknesses in government policies in the field of women's empowerment in realizing gender equality and how to reconstruct the law to realize better Gender Equality. The method used in this study uses an empirical juridical approach supported by a normative approach with the paradigm used by the constructivism paradigm. Results of the research show that the Weaknesses in government policies in the field of women's empowerment in realizing equitable gender equality is that there is still low knowledge and skills (competence) of HR planners in OPD regarding how to prepare PPRG (GAP and GBS), due to weaknesses in regulations in Permendagri No. 67/2011, which has not regulated the obligation of PUG Pojka to organize and provide training to focal points in each SKPD. Therefore, a legal Reconstruction of government policies in the field of Women's Empowerment in realizing a just Gender Equality is needed, namely by following up on regulations that require the implementation of gender mainstreaming in regional development by reconstructing Article 10 of Permendagri No. 67/2011, namely by regulating the obligations of PUG Working Groups to organize and provide training and at the same time providing sanctions for violations of duties by PUG Working Groups.

Basaloid squamous carcinoma of the uterine cervix is a rare tumor type characterized by an ulcerated, infiltrating growth pattern; nests or cords of small basaloid cells; prominent peripheral palisading of cells in the tumor cell nests; and the absence of significant stromal reaction. The characteristic microscopic features are nests, lobules, trabeculae and groups of round to oval basaloid tumor cells. These tumor cells are small with high nuclear cytoplasmic ratio and shows peripheral palisading. There may be areas of comedo type necrosis and areas showing typical squamous cell carcinoma differentiation.

This research article presents a numerical simulation of the extensive severe cyclonic storm Fani and its impact along the coast of Bangladesh, which made landfall in the coastal region of Odisha, India, on May 3, 2019. A semi-implicit finite difference method in Cartesian coordinates was employed in this study to solve vertically integrated shallow water equations. The approach allowed for effective forecasting of the storm Fani's impact on the region of choice. Our considered physical domain is discretized with high-resolution gird to cover all the big and small offshore islands. The model predicted water levels for a total of sixteen coastal stations of the Bay of Bengal along the coast of Bangladesh (from 2 May to 03 May 2019, at 3-h interval). Simulated water levels are found closely co-related to the reported data. The simulation results demonstrate that the semi-implicit finite difference method is an effective tool for simulating the storm surge and flooding caused by any severe cyclonic storm. The study also shows that the storm surge and flooding caused by Fani were significant, with a maximum surge height of over 5 meters in some areas. The simulated results provide insights into the spatial and temporal evolution of the storm surge and flooding, which can be useful for designing and implementing appropriate disaster management strategies in the affected regions. Overall, this research article contributes to the scientific understanding of the behavior of severe cyclonic storms and the associated storm surge and flooding, and provides a valuable tool for policymakers and stakeholders to develop and implement effective disaster management strategies in cyclone vulnerable coastal regions.

Background: Type 2 diabetes mellitus is a prevalent hereditary condition that has multiple genetic risk factors as well as environmental influences. Aim: The Work aimed to find if there is an association between the presence of Single Nucleotide Polymorphism of the Adiponectin gene & its association with type II diabetes in Egyptian patients. Material & Techniques: This case-control research had been conducted at Molecular Biology and Biochemistry, Genetic Engineering & biotechnology institute, university of Sadat city. This research had been conducted on eighty patients; separated into 2 groups diabetic group and the control group. Results: significant reduction in adiponectin level in type II diabetes studied cases compared to normal control subjects (p <0.001). GG genotype is significantly more predominant in type 2 diabetes (54%) while the GT genotype is more predominant in control (60%) (p-value =0.04)., while no variation in allele distribution among both groups (p value=0.6). Conclusion: In studied cases with type 2 diabetes, there was a significant reduction in adiponectin levels in type II diabetes patients. GG genotype is significantly more predominant in type 2 diabetes. The genotype GG significantly rises the risk of occurrence of type 2 diabetes.

As a follow-up to an earlier report on the antihyperlipidaemic activity guided fractionation study on the chloroform extract from the sclerotia of the edible mushroom Pleurotus tuber regium, this present study is reporting the isolation of a sesquiterpene enol carboxylic from the active chromatography fraction of the chloroform extract of this edible mushroom. The purity of the compound was confirmed from TLC and Melting point determination. The chemical structure was elucidated using spectroscopic techniques (Mass spectrometry, 1&2D Nuclear magnetic resonance and Infra red spectroscopy). The isolated compound coded as compound P, exhibited molecular mass of 256 with molecular formular of C14H24O4 and from the 1 &2D NMR and IR analyses, the compound P was identified as a sesquiterpene enol carboxylic acid with a sytemic name of 2,3-dihydroxy-10-propylcyclodec-2-ene-1-carboxylic acid.