ORIGINAL RESEARCH ARTICLE | Sept. 3, 2023
The Trickster Archetype in Oral Literature: Unravelling Universality and Pedagogical Power across World Cultures
Agbeye Oburumu
Page no 240-247 |
DOI: 10.36348/sjhss.2023.v08i09.001
This paper delves into the intricate character of the trickster as portrayed in oral literature while conducting a comprehensive survey to explore the universality of this intriguing figure across diverse world cultures. The investigation draws inspiration from Carl Jung's proposition that these archetypal manifestations in cultural and religious literature stem from the "collective unconscious," a profound thread of consciousness connecting all human beings and societies worldwide. The essay emphasises the distinctiveness of each trickster's personality within their respective cultures while also highlighting the common traits shared among all tricksters. Typically perceived as an entertainer, teacher, judge, and sage, the trickster embodies both humorous and serious aspects of life, encompassing a wide range of roles from rewarding to punishing. Furthermore, the study asserts that the trickster character goes beyond being a mere fictional element in oral literature; rather, it serves as a powerful tool for pedagogy and satire. The study advocates for the deliberate collection and documentation of folktales. These tales serve as valuable raw materials for future research, offering insights into the cultural intricacies and shared human experiences across the globe.
ORIGINAL RESEARCH ARTICLE | Sept. 3, 2023
Clinical and Radiological outcome of Gartland Type-III closed supercondylar fracture of humerus in Children treatment by percutaneous K-wires fixation
Md. Insanul Alam, Hosne Ara, Md. Faridul Islam, Md. Ismail Hossain, Razia Sultana, Md. Mahbubul Alama, Khaleda Akter, Md. Saidul Hoque, Zubayer Ashraf, Md. Anisuzzaman
Page no 593-598 |
DOI: 10.36348/sjmps.2023.v09i09.001
Introduction: Supracondylar fracture of the humerus is the most common fracture of the elbow in children and displacement is common. Main problem regarding management of early supracondylar fracture are obtaining and maintaining reduction as they commonly present in the emergency department with varying degrees of soft tissue swelling. Objective: To assess the Clinical and Radiological Outcome Type III Closed Supracondylar Fracture Of Humerus in Children treatment by percutaneous K-wires fixation. Methods: This study was carried out at the NITOR, over a period of 24 months between January 2015 to December 2016. The total number of patients were 30. All patients suffering from closed supracondylar fracture of humerus in children. Each Gartland type-III closed Supracondylar Fracture of humerus among supracondylar Fracture in children attended at emergency, outpatient department and admitted in NITOR. Results: A total number of 30 patients were enrolled in this study as per inclusion and exclusion criteria. Diagnosis of the supracondylar fracture of humerus was made by history, clinical examination and radiological evidence. The youngest patient in our series is 3 years old and the oldest is 12 years. Majority were in 5-8years. Among 30 patients mean age was 6.85 years with SD = ± 2.37 years. In the present series, maximum patients were male 22 (73.3%) and 8 (26.7%) patients were female. Male female ratio 2.75:1. Male patients were predominant in this study. The results are shown in table-I. In the present series, 19 (63.3%) with left sided supracondylar fracture of humerus and 11(36.7%) presented with right sided supacondylar fracture of humerus. The results are shown in Table-II. Out of 30 cases 15 (50%) cases gave history of fall from tree, 6(20%) cases gave history of fall from bed, 4(13.3%) cases gave history of fall during playing, 5(16.7%) cases gave history of RTA due to fall from bicycle. In the present series, postero-medial fracture was found in 18(60.0%) cases and postero-lateral fracture in 12 (40.0%) cases. Out of 30 patient’s about 16 (53.3%) of the patient’s was operated between (13-18) hours of receiving injury, 11 (36.7%) with in (7-12) hours and 1 (3.3%) within (0-6) hours of injury and 2(6.7%) with in (19-24) hours of injury, mean interval between injury and Operation was 8.06 ± 5.52 hours. Out of 30 patient’s, 22 (73.3%) of the patients stayed in the hospital for 1 day and 8 (26.7%) of the patients stayed in the hospital for 2 days. The mean duration of hospital stay was 1.26 ± 0.45 days. In this series, among 30 Patients, 27(90.0%) had radiologically sufficient callus formation and 3(10.0%) patients had no sufficient callus formation. Functional outcome was satisfactory result (Excellent, Good and Fair) were 27(90.0%) and unsatisfactory result (poor) was 3 (10.0%). Conclusion: Finally, the result shows that in Gartland type-III closed supracondylar fracture of the humerus, closed reduction and stabilization by two lateral parallel percutaneous 'K'-wires is the good method for treatment.
ORIGINAL RESEARCH ARTICLE | Sept. 3, 2023
Bitar Nazarin Ganga Dogarau a Hausa
Dr. Muhammad Mustapha Umar, Dr. Abdulkadir Abubakar Zailani
Page no 368-371 |
DOI: 10.36348/sijll.2023.v06i09.001
A clause which depends on some other clauses for its meaning is called relative clause. Relative clause can be introduced by a relative pronoun that agrees in number and gender with the head noun. This paper intends to only discuss how to constitute relative clause using only relative pronouns. This paper is product of data collection from documentary sources to obtain a sample of related examples. The finding of this paper revealed three strategies used to form some relative clauses in Hausa.
ORIGINAL RESEARCH ARTICLE | Sept. 3, 2023
Nonlinear Dynamic Analysis of Lumped Soil Mass Model against Seismic Loading
S. M. Tahmidur Rahman
Page no 158-177 |
DOI: 10.36348/sjce.2023.v07i08.001
Soil yielding mechanisms and seismic load responses are the key areas of study. The true behavior of soil is revealed by nonlinear analysis. A clump of dirt is used for the analysis. In this study, the Finite Element Model (FEM) forms the basis for the mathematical formulas. Soil analysis in the case of a lumped mass takes into account the soil's one DOF, two DOF, and multi DOF degrees of freedom. In order to determine soil characteristics for MDOF, a soil bore log must be employed. In the instance of MDOF, the soil is composed of 12 distinct layers. SAP 2000 is used to conduct a nonlinear time-history analysis for this research. The hysteresis loops of nonlinear elastic, completely flexible soil undergo permanent deformation. Therefore, it is possible to get insight into the behavior of soil mass during an earthquake by studying lumped soil mass. The soil's nonlinear behavior is investigated using a variety of linear completely plastic hysteretic loops. Soil characteristics are shown to be crucial in this regard. Inadequate soil stiffness may result in persistent deformation, which in turn can lead structures to lean out of alignment. It is also noted that near the soil's surface, amplification is greatest.
ORIGINAL RESEARCH ARTICLE | Sept. 2, 2023
Efficacy of Endoscopic Biliary Drainage in Pancreatic Adenocarcinoma
Mohamed Borahma, Emna Benour, Fatima Zahra Chabib, Aimé-Parfait Irambona, Imane Benelbarhdadi, Fatima Zahra Ajana
Page no 470-472 |
DOI: 10.36348/sjm.2023.v08i09.001
Introduction: The incidence of pancreatic cancer has increased in recent years. Pancreatic cancer accounts for 2.9% of all cancers in our registry. Biliary drainage is frequently required and is mainly indicated in cases of cholangitis and/or hyperbilirubinemia. Our work aimed to evaluate the efficacy of endoscopic biliary drainage in pancreatic adenocarcinoma. Materials and Methods: A cross-sectional study was conducted between May 2019 and October2021 and included all patients with pancreatic adenocarcinoma, who underwent endoscopic biliary drainage. Results: Forty-five patients were enrolled, including 23 males and 22 females with a sex ratio of 1.04. The average age was 61 ± 10.9 years. Seven patients (16%) had a history of diabetes, 7 patients (16%) had a history of smoking, 4 patients (9%) had a history of alcoholism, 27 patients had no history. All patients were presented with cholestatic jaundice and 17 patients (37.7%) with abdominal pain. After morphological evaluation, only 11% of our patients had a resect able tumor and 89% of the patients had an unresectable tumor. Thirty-eight patients (84%) had a metallic biliary stent and seven patients (16%) had a plastic biliary stent. Biliary drainage associated with antibiotic therapy allowed controlling cholangitis in 98% of cases, only one patient (2%) died after drainage from sepsis. The average total bilirubin level before biliary drainage was 19.7 mg/dl and 4.8 mg/dl 2 weeks after drainage (P = 0.51), representing a decrease of 76%. Conclusion: Endoscopic biliary drainage is the gold standard for relieving the obstruction in pancreatic adenocarcinoma. Most of our patients (89%) had an unresectable pancreatic tumor. Drainage was ensured respectively by the metallic stent and plastic stent in 84% and 16% of patients and provided very sufficient biliary drainage with a decrease of 76% of bilirubinemia at 2 weeks post drainage.
ORIGINAL RESEARCH ARTICLE | Sept. 2, 2023
Understanding the Dynamics of Multi-Dimensional Poverty Index: BIMARU States: An Econometrics Approach
Dr. Vikas Deepak Srivastava, Dr. Vijay Kumar, Prabhu Narayan Srivastava
Page no 400-406 |
DOI: 10.36348/sjef.2023.v07i09.001
The research study analyzes multidimensional poverty in seven states of India, namely Bihar, Chhattisgarh, Jharkhand, Madhya Pradesh, Odisha, Rajasthan, and Uttar Pradesh. The study focuses on three key dimensions of poverty: infant mortality rate, birth rate, and educational dropout rates at both primary and upper primary levels. Additionally, the study examines the availability of basic amenities such as clean cooking fuel, improved sanitation facilities, and safe drinking water. By calculating the Multidimensional Poverty Index (MPI), the study ranks the states based on their performance in these dimensions. Madhya Pradesh emerges as the top-performing state with the lowest MPI score of 0.310745, followed by Uttar Pradesh, Rajasthan, Chhattisgarh, Odisha, Bihar, and Jharkhand. The study reveals that despite having relatively low MPI scores, Madhya Pradesh and Uttar Pradesh still struggle with high infant mortality rates and birth rates. This indicates the need for targeted interventions to improve healthcare and family planning services in these states. Additionally, the study highlights the importance of education in poverty reduction. It identifies Jharkhand and Chhattisgarh as states with the highest primary and upper primary education dropout rates. This emphasizes the need for improving the quality of education and implementing strategies to encourage school completion. It also states the importance of addressing issues related to healthcare, education, and basic amenities in order to reduce poverty and improve overall well-being. The normalized index approach used in this study provides a comprehensive and objective measure of poverty, enabling policymakers and stakeholders to make informed decisions and allocate resources effectively.
ORIGINAL RESEARCH ARTICLE | Sept. 2, 2023
Antihyperglycemic and Histological Effect of Aloe vera on Alloxan-Induced Diabetes in Wistar Rats
Sample Dede, Joshua Charles Isirima, Sokiprim Akoko
Page no 120-128 |
DOI: 10.36348/sijtcm.2023.v06i08.001
Introduction: Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia and is associated with various complications if not properly managed. Aloe vera, a medicinal plant with diverse pharmacological properties, has shown promise as a potential therapeutic intervention for diabetes. This study aimed to investigate the antihyperglycemic and histological effects of Aloe vera in an alloxan-induced diabetic Wistar rat model. Method: Forty-eight Wistar rats were divided into six groups and treated with different regimens of Aloe vera and metformin, a standard antidiabetic drug. The effects of the treatments on blood glucose levels and histology of the pancreas, liver, and kidney were evaluated. Result: The results of the study revealed that alloxan injection induced hyperglycemia and pathological changes in the pancreas, liver and kidney of Wistar rats. The treatment with 100mg/kg, 200mg/kg and 400mg/kg of Aloe vera significantly reduced blood glucose levels in a dose-dependent manner. Additionally, Aloe vera administration preserved the histological integrity of the pancreas, liver, and kidney in diabetic rats. This preservation of organ histology can be attributed to the antioxidant, anti-inflammatory, and tissue-protective properties of Aloe vera. Conclusion: Aloe vera demonstrated antihyperglycemic effects and preserved organ histology in an alloxan-induced diabetic Wistar rat model. The bioactive compounds present in Aloe vera are believed to contribute to these effects. Aloe vera holds potential as an alternative or adjunctive therapy for diabetes management, but its clinical efficacy and safety need to be further explored.
ORIGINAL RESEARCH ARTICLE | Aug. 31, 2023
Prevalence of Antibiotics Resistance among Patients in Iraqi Hospitals
Wifaq M. Ali Alwatar, Suha A. Al Fakhar, Saad Hasan Mohammed Ali, Khalil Ismail Abid Mohammed, Jenan M. Mousa
Page no 118-126 |
DOI: 10.36348/sjls.2023.v08i07.005
Background: Antibiotics are medicines that fight bacterial infections. If they are used probably, they can save lives. Still there is a growing problem of antibiotic resistance. It happens when bacteria undergo some mutation and become able to resist the effect of an antibiotic. Objectives: This cross sectional study was to determine the prevalence of antibiotics resistance among group of patients and to know the causes that lead to antibiotic resistance crisis to compare the results with previous studies concerning this subject in order to identify the risks of antibiotic resistance to offer some solutions (if any) that can minimize this problem at Iraqi hospitals. Methodology: This cross sectional study was conducted from May to October 2019. The sample was 128 patients (their specimens were cultured and antibiotic sensitivity was tested) especially toward a group of antibiotic. Results: At the end of this study the result showed that a higher group of resistance especially to penicillin group and a lower rate to azithromycin, another finding was the bacteria which infect (admitted in patients) were resistant to multiple drugs than those which infect (out patients). Conclusion: A high resistance to penicillin group, Staphylococcus aureus was found to be the most resistant microorganism as culture results showed.
ORIGINAL RESEARCH ARTICLE | Aug. 31, 2023
Constraints to Environmental Hygiene Practices among Boarding Students in Awka-South L.G.A of Anambra State
Onyejieke Josephine Nwadimkpa, Dr. A. O. Onyeaso
Page no 323-331 |
DOI: 10.36348/jaep.2023.v07i08.011
This study investigated constraints to environmental hygiene practices among boarding students in Awka-South L.G.A of Anambra State. Three research questions and two hypotheses guided the study which adopted descriptive e survey research design. The population for this study consisted of the 5336 boarding students (2,348 male and 2,988 female) in the 10 secondary schools in Awka-south Local Government Area of Anambra State. A multi-stage sampling procedure was adopted to draw the sample size of 800 boarding students. A questionnaire designed by the researcher entitled: “Constraints to Environment Hygiene Practices among Boarding Students Questionnaire (CEHPABSQ)” was used for data collection. The instrument was properly validated and a reliability index of 0.76 was obtained using Cronbach Alpha. Data generated were analysed with mean and standard deviation to answer the research questions while z-test was used to test the hypotheses at 0.05 level of significance. Results of the study revealed that constraints to environmental hygiene practices to include inadequate provision and maintenance of sanitary facilities by school authorities with aggregate mean scores of 2.90 > 2.5 criterion mean. Based on these findings, it was concluded that school authorities and parents should address environmental constraint without any compromise for promotion of good health of the students. Based on the conclusion the following recommendations were proffered; school authorities should ensure that there is constant water supply in their schools for good environmental hygiene practices.
SUBJECT CATEGORY: HUMAN ANATOMY | Aug. 31, 2023
Sole Dermatoglyphic Pattern of Elele People, Rivers State, Nigeria
Gospel Chimenma Dimkpa, John Nwolim Paul, Confidence Waribo Ihua, Henry Ajulor Amadi-Ikpa, Anelechi Kenneth Madume, Monday Didia, Hebinuchi Amadi, Chizam Treasure Nwokanma, Chimezunem Mandah, Ada Mercy Ugbe
Page no 86-91 |
DOI: 10.36348/sb.2023.v09i07.002
Background: There is no known study on the sole dermatoglyphic pattern of the Elele people that could serve as their baseline data; hence, this study was done to provide baseline data for the sole dermatoglyphic patterns of the Elele people of the Ikwerre ethnic group in Rivers State, Nigeria. Material and methods: A Non-experimental analytical and cross-sectional study. 200 subjects [males 107, females 93] pure-breed indigenes of Elele extraction were purposively sampled, on the basis of both parents and grandparents to the fourth generation being natives of Elele. Participants who had distortions and malformations of the sole were excluded from the study. The parameters studied includes: the dermatoglyphic patterns on the soles and toes participants in Elele, Rivers State, Nigeria. The patterns on the sols and toes were observed and classified following the standard procedure. Result and Discussions: The study also showed the following distribution on the toe for the males [arch 253 (47.5%), whorl 134(25.2%), loop 145(27.3%)]; the females on the other hand had [arch 383(40.9%), whorl 289(30.9%), loop 264(28.2%)]. The arch pattern was most frequent in both genders. And the total distribution showed thus: arch 636(43.3%), whorl 423(28.8%), loop 409(27.9%). Dankmeijer’s index [male 1.32, female 1.880, total 1.50]; Pattern Intensity Index [male 84.2, female 41.3, total 125.5]. The results show that the pattern intensity index is greater in females than in males. While the Dankmeijer’s index was higher in males than females. Conclusion: The study showed that the loop pattern was most frequent on area I and II in both genders, whorl pattern was most frequent on area I and II in the males and area I and IV in the females, and the arch pattern was most frequent on area I and II in both genders. The absence of whorl on the toes of males was seen as a characteristic pattern for the males in Elele.
ORIGINAL RESEARCH ARTICLE | Aug. 31, 2023
Legal Reconstruction of Standard Agreements with Exoneration Clauses on Peer-To-Peer Financial Technology Based on Justice Values
Dwi Afni Maileni, Adi Sulistiyono, Anis Mashdurohatun
Page no 461-466 |
DOI: 10.36348/sijlcj.2023.v06i08.010
This research aims to examine and analyze standard peer-to-peer lending contract agreements with exoneration clauses that are not based on the value of justice. To study and analyze the weaknesses that arise in implementing peer-to-peer lending Financial Technology agreements at this time. To study and analyze the reconstruction of standard agreements with exoneration clauses on peer-to-peer lending Financial Technology based on the value of justice. The method used in this research is sociological juridical. The paradigm in this research is constructivism. The theory used in this study is the Pancasila legal theory of justice as a grand theory, the working theory of law as a middle ranged theory, and the progressive theory as an applied theory. Based on the research conducted, it was found that standard peer-to-peer lending contract agreements with exoneration clauses that are not based on the value of justice are due to overlapping rules, the lack of reach of law enforcement in standard contracts made by Financial Technology institutions, and the influence of globalization which has resulted in the growth of financial institutions. technology is getting out of control. So it is necessary to amend the provisions of the Financial Services Authority Circular Letter Number 13/Seojk.07/2014 in which the financial services business actors are not only entitled to make procedures regarding standard agreements, but it is necessary to regulate the position of Financial Technology institutions in the Republic of Indonesia Financial Services Authority Regulation Indonesia Number 10/Pojk.05/2022 concerning Information Technology-Based Joint Funding Services is clear. It is necessary to regulate information on the process of public complaints against the OJK, especially in the case of Financial Technology institutions. It is also necessary to control sanctions related to Financial Technology that violates the law, especially in standard agreements with exoneration clauses.
ORIGINAL RESEARCH ARTICLE | Aug. 31, 2023
Comparative Assessment of the Immunological Significance of Semaphorin 5A and Anti-Cyclic Citrullinated Peptide Antibodies in Iraqi Patients with Rheumatoid Arthritis
Khalil Ismail AbidMohammed, Ali Abdul-Ameer Oglah, Mohammed Hadi Alosami, Athraa Y Al-hijazi
Page no 111-117 |
DOI: 10.36348/sjls.2023.v08i07.004
The objective of this research was to assess the predictive potential of Semaphorin 5A in comparison to Anti-Cyclic Citrullinated Peptide antibodies for forecasting disease progression and treatment responses among Iraqi patients with Rheumatoid Arthritis (RA). Conducted as a case-control study, the investigation encompassed a total of 150 participants, comprising 100 RA patients and 50 healthy individuals. The study took place at Baghdad Teaching Hospital over the period from November 2021 to February 2022. Enrolled participants were selected based on the 2010 criteria established by the American College of Rheumatology. The levels of biomarkers were assessed using the enzyme-linked immunosorbent assay (ELISA) method. The findings demonstrated a noteworthy elevation in the levels of both ACCP and Semaphorin 5A among RA patients compared to the control group (p<0.001). Furthermore, these levels were found to be higher in individuals with active disease as opposed to those with inactive disease. In both active and inactive disease states, the levels of both ACCP and Semaphorin 5A remained considerably higher compared to the levels observed in the healthy control group (p<0.001). In patients who had not undergone treatment, the levels of both ACCP and Semaphorin 5A exhibited considerably greater significance compared to those who received Methotrexate or etanercept (p<0.001). A noteworthy and positive correlation was observed between ACCP and Semaphorin 5A, with a correlation coefficient of 0.476 (p<0.001). The sensitivity for ACCP and Semaphorin 5A was determined to be 72% and 83% respectively, while the specificity values were 98% and 76%. The study's conclusion highlighted the promising prognostic potential of both ACCP and Semaphorin 5A, establishing them as potential biomarkers for distinguishing between Rheumatoid Arthritis patients and healthy individuals. Predict disease activity and response to methotrexate or etanercept. Active disease patients and without treatments patients ACCP and Semaphorin5A levels were higher than inactive and received treatments (methotrexate or etanercept).
ORIGINAL RESEARCH ARTICLE | Aug. 31, 2023
Influence of Parents’ Expectations on Course Choice in Vocational Training Centres in Taita Taveta County, Kenya
Raphael Mwasi Chola, Hoseah Kiplagat, Joseph Mubichakani
Page no 317-322 |
DOI: 10.36348/jaep.2023.v07i08.010
This study examines the relationship between parental influences and a young person's job decision, particularly in the context of choosing courses before enrolling in higher education institutions like Vocational Training Centres (VTCs). The research aims to understand how trainees' perceptions of parental influential factors predict their career choice intention in Taita Taveta County, Kenya. The study analysed data from 2,386 trainees and 29 principal managers in Taita Taveta County VTCs in 2022 using a descriptive survey design. Data was collected using structured interviews and questionnaires. Male trainees comprising 63.1%) were more than female participants 261 (36.9%) (χ2= 6.76, d.f.=1, p = 0.0093). In 2022, 21-year-old trainees in Taita Taveta County VTCs enrolled in car repair, with 18.9% choosing this course, while 0.1% chose agriculture. Parents were the most influential factor, with 58.50% of trainees agreeing with this statement (35.70%) (χ2= 139.95, d.f.=4, p< 0.0001). When asked if other family members had the most impact on their decision to enrol in a course, the majority of respondents 351 (49.60%) agreed with the statement (χ2= 93.53, d.f.=4, p< 0.0001). In relation to opinion that counsellors had greatest influence in their course choice, majority of the respondents agreed 384(54.30%) while the rest disagreed (χ2= 93.53, d.f.=4, p< 0.0001). Also, when the trainees in the VTCs were asked whether the teachers had influence in their course choice, most of them 405(57.1%) agreed, with a significant difference (χ2= 122.93, d.f.=4, p< 0.0001). Parents’ expectations significantly predicted course choice, F 0.05 (1,706) = 6.381, p< 0.05, which indicates that parents’ expectations play a significant role in shaping the course choice (b= 0.599, p < 0.05). The study found trainees' course selections influenced by parents, relatives, counsellors, and instructors, but their personalities, intellectual capacities, and practical and theoretical skills limited their participation. Parents, family members, counsellors, and trainers should influence trainees' course selections based on personalities, intellectual prowess, KUCCPS needs, and course management capacity, ensuring beneficial outcomes.
ORIGINAL RESEARCH ARTICLE | Aug. 30, 2023
Development of a Pharmaceutical Formulation Containing Clove (Syzygium aromaticum) Extract for the Management of Oral Candidiasis
Ashraf O. Abdellatif, Alaa-Aldeen A. Mohamed, Safa S. Seed-Ahmed, Mehaira M. Said, Noora A. Mohamed, Kamal A. A. Mohammed, Raja Y. Alghadi, Mohammed O. Alqamar
Page no 160-165 |
DOI: 10.36348/sjbr.2023.v08i08.005
Introduction: Oral candidiasis is a common fungal infection caused by various yeast species, including Candida albicans, Candida krusei, Candida parapsilosis, Candida tropicalis, and Candida glabrata. Clove, a well-known plant in traditional medicine, has been used as an antiseptic remedy for diverse infections, including those affecting the oral cavity induced by yeasts and bacteria. The emergence of resistance to numerous antifungal agents among Candida species necessitates exploring alternative treatments. Hence, this study aims to evaluate the antimicrobial activities of clove extract and develop a suitable pharmaceutical formulation containing clove extract for managing oral candidiasis. Method: The antimicrobial culture and sensitivity test were conducted using the agar-well diffusion assay, evaluating different concentrations of clove extract against Candida albicans. The minimum effective concentration was then formulated into a gel dosage form, and its antimicrobial activity was assessed, comparing it with miconazole oral gel. Result: The results showed that the prepared clove extract gel had antifungal effects on Candida albicans that were similar to those of the miconazole oral gel. The zone of inhibition for the clove extract gel was measured at 25 mm, while the miconazole gel showed a zone of inhibition of 27 mm. Conclusion: The results of this study show that clove extract gel may be an effective antifungal agent, especially against Candida albicans. This suggests that it may be a promising herbal alternative to conventional medicines for treating oral candidiasis.
ORIGINAL RESEARCH ARTICLE | Aug. 30, 2023
Association of Preoperative Neutrophil to Lymphocyte Ratio in Patients with Epithelial Ovarian Tumor
Shahana Rahman, Sabera Khatun, Dilruba Ferdous, Nazneen Choudhury, Towhida Nazneen, Reeta Rani Sarkar, Jannatul Ferdous
Page no 338-344 |
DOI: 10.36348/sijog.2023.v06i08.006
Objective: Ovarian cancer is a leading cause of gynecological cancer death among women worldwide. Silent growth of the tumor and challenges associated with preoperative evaluation of an ovarian mass are responsible for late presentation. The aim of this study was to evaluate the association between preoperative neutrophil to lymphocyte ratio (NLR) and epithelial ovarian tumor. Methods: A total of 60 patients diagnosed with ovarian tumor who fulfilled the selection criteria were recruited as study population. The ovarian tumor was subsequently diagnosed by histopathological analysis as either malignant epithelial ovarian tumor or benign epithelial ovarian tumor. Preoperative demographic and laboratory variables are reviewed in all patients. Association of preoperative NLR was assessed in benign and malignant epithelial ovarian tumor using unpaired t test. Receiver operating characteristics curve was used to calculate optimal cut off value for NLR to predict ovarian cancer preoperatively. A p-value of <0.05 was considered to indicate statistically significant differences. Results: There was statistically significant difference between the groups in terms of age, menopausal status, and NLR (all p=0.001, except for menopausal status p=0.007). NLR value was significantly higher (3.47±1.52) in patients with malignant ovarian tumor (p=0.001) than that of benign ovarian tumor. Higher NLR value predicted ovarian cancer at the cut-off value of 2.78, with 75.6% sensitivity and 78.9% specificity (95% CI, 0.97-1.0). Conclusion: Malignant epithelial ovarian tumor is associated with higher NLR. Preoperative NLR may be helpful for prediction of malignant ovarian tumor.