Advances in Transgenic Technology for Crop Cultivation and Stomatal Regulation as Potent Role in Agriculture
Muhammad Ehsan Haider, Muhstaq Hussain, Sikandar Ali, Muhammad Riaz, Nasir Hussain, Muhammad Saleem, Shoaib Shafique, Saifullah
Page Numbers : 86-90
DOI : 10.36348/sijb.2021.v04i08.001
Gossypium hirsutum L. is most essential cash crop which provide fiber to fabric industries globally. Cotton is the world leading crop, is plenteous and produced economically, manufacturing products of cotton relatively cheap. The threads can be prepared in to a wide-ranging fabrics variety like light-weight laces and voiles to heavy-weight sailcloth’s and heavy piled velveteen’s, appropriate for large diversity of wearing apparel, furnishings and much industrial consumption. Fabrics from cotton can be tremendously long-lasting and resilient to scratch. Reduction of water loss through leaves is a crucial phenomenon in cotton plants under drought stress. ABA is one of the most important stress hormones and participates in various crucial physiological processes during the plant life cycle, including stress responses, development and reproduction. Exogenous application of osmo protectants and various plant growth regulators have been found effectively to enhance drought tolerance in cotton. To increase the tolerance in cotton against drought stress, transcription factors are excellent candidates for the plant scientists. Cotton is an important cash crop worldwide. Although it is classified as one of the most salt-tolerant major crops and considered a pioneer crop in reclamation of saline soils, its growth and development as well as yield and fiber quality are negatively affected by excessive salts in the soil.
Original Research Article
Aug. 30, 2021
Role of Biochemical Markers for Evaluation of Oxidative Stress in Diabetic Cataract
Kim Sharma, Dr. Yogita Soni
Page Numbers : 82-85
DOI : 10.36348/sijb.2021.v04i07.002
Background: -Ocular complications are common in diabetes and cataract becomes the major cause of blindness in diabetic patients. Objective: Oxidative stress was assessed by estimating lipid peroxidation product (LPO) in the form of MDA and non-enzymatic antioxidant vitamins C in the serum. Methodology: A number of 100 cases of diabetic cataract in the age group of 45-70 years, compared with 100 healthy controls. Results: Serum levels of MDA and Vitamin C between cataract cases and control groups were found to be statistically significant (P<0.0001). Conclusion: The present study revealed that low levels of antioxidants and increased oxidative stress may have a role to play in the etiopathogenesis of the diabetic cataract.
Aug. 18, 2021
Piliostigma thonningii (Fabaceae): A Comprehensive Review on its Traditional Medicinal Uses, Phytochemistry, Pharmacology and Toxicology
Medicinal plants have long been used globally for the management and treatment of diverse disease conditions. They are endowed with diverse secondary metabolites responsible for the therapeutic effects they exhibit hence the possibility of discovering novel, effective and affordable therapeutic targets with limited side effects. Scientific investigation of these medicinal plants has witnessed an upsurge in recent times. Piliostigma thonningii (Schum Milne-Redhead) commonly known as ‘‘camel’s foot’’ and ‘‘monkey bread’’and locally as ‘‘kalgo’’ in Hausa, ‘‘Omukpakpa ajalu’’ in Igala, ‘‘abafe’’ in Yoruba, ‘‘nyihar’’ in Tiv, ‘‘mchekeche’’ in Swahili and ‘‘Kharub’’ in Arab is distributed widely in tropical and subtropical regions of Africa. The different parts of the plant are known for the treatment and management of dysentery, fever, respiratory ailments, snakebites, hookworm and skin diseases, and gastro-intestinal tract problems among others. Although promising scientific reports have been published on the various parts of P. thonningii, no review comprehensively summarizes its traditional uses, phytochemistry, pharmacology, and toxicology. Therefore, this review aims to provide a critical and comprehensive evaluation of the traditional uses, phytochemistry, pharmacological properties and toxicology of P. thonningii as well as offer suggestions for future investigations.
July 17, 2021
Heavy Metal Pollutions in Soil: Sources, Speciation and Remediations; Review
Yohannse Habteyesus Yitagesu
Page Numbers : 57-65
DOI : 10.36348/sijb.2021.v04i06.001
The level of heavy metals above the permissible limit is toxic to human being as well as to animal welfare. The heavy metals enter the surrounding environment by natural and though anthropogenic activities. Soil erosion, natural weathering, mining, industrial effluents, urban runoff, sewage discharge, inorganic fertilizers, insecticides, herbicides, industrial emissions and transportations are some of the various sources of heavy metals induced to the environment, waterbody, soil and foods. Many instrumental analytical methods may be employed to measure the concentration of heavy metals in various samples. The most common techniques are atomic absorption spectrometry (AAS); atomic emission/ fluorescence spectrometry (AES/AFS); inductively coupled plasma mass spectrometry (ICP-MS); inductively coupled plasma optical emission spectrometry (ICP-OES); neutron activation analysis (NAA), X-ray fluorescence (XRF); and anodic striping voltammetry (AVS). The detection level of metals quantification depends on the instrument, method extractions and speciation. There are physical, chemical and biological techniques of heavy metals remediations in soil and human bodies. Biochar is one of the organic materials reduce the level of heavy metals, the plant species such as: Salix spp. (Salix viminalis, Salix fragilis), Castor (Ricinus communis), Corn (Zea mays),Populus spp. (Populus deltoides, Populus nigra, Populus trichocarpa), Jatropha (Jatropha curcas L.), Populus deltoides, Brassica juncea, Astragalus bisulcatus, Populus canescens can also remediate heavy metals from the contaminated soil. Chelate therapy ridding the body heavy metals with a chemical like Ethylene Diamine Tetraacetic Acid (EDTA) effective chelation of removing metals from body blood. Due to the increasing trend of HMs contamination, the negative impact on plants, environments and other organisms, it is important to mitigate the toxicity by developing effective and environmentally safe technologies. This paper therefore gives highlights of heavy metals sources, techniques of analysis and remediations.
Original Research Article
June 11, 2021
Non-High-Density-Lipoprotein Cholesterol in Morocco Hemodialysis Patients
A. Marou, A. Laraqui, L. Balouche, Y. Bamou, F. El Boukhrissi
Page Numbers : 52-56
DOI : 10.36348/sijb.2021.v04i05.001
Introduction: Disturbances in lipid profile are very common in hemodialysis patients. Non-high-density lipoprotein cholesterol (non-HDL-c) has been proposed as a good predictor of atherogenic potential in the general population, but there is little data on this parameter in hemodialysis patients. The objective of this study is to assess the prevalence of lipid abnormalities in a series of hemodialysis patients and to appreciate the contribution of non-HDL-c in the identification of non-traditional risk factors related to lipoprotein subclasses. Materials and methods: we performed a case-control study which included 100 chronic hemodialysis patients, from October 2014 to February 2015. We evaluated anthropometric markers and lipids parameters in HD patients and control patients, and the correlation between them was investigated. Results: One hundred chronic hemodialysis patients with a mean age of 48 ± 17 years participated in this study. The most common lipid abnormality was a decrease in HDL-c (47%), followed by an increase in HDL-c (27%) and hypertriglyceridemia (20%). Total cholesterol (TC), LDL-c, and CT/HDL-C ratio are significantly higher in the group of patients with high non-HDL-c compared to the low non-HDL-c group. In addition, a significant correlation was demonstrated between the levels of non-HDL-c and either LDL-C (r = 0.917, p = 0.000) or TC (r = 0.941, p = 0.000). Conclusion: Our study suggests that non-HDL cholesterol is an indicator valuable in the diagnosis, monitoring of dyslipidemia and assessment of cardiovascular risk in hemodialysis patients. It amply deserves to be included in the parameters of the lipid balance within the framework of the follow-up of hemodialysis patients.
May 23, 2021
Enzyme Vs Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia
Hadia Naseem, Iqra Kanwal, Muhammad Haseeb Anwar Tarar, Sabahat Irfan, Taiyyibah Basharat, Muhammad Adnan, Nabeela Fatima, Usman Ghani
Page Numbers : 42-51
DOI : 10.36348/sijb.2021.v04i04.002
Cancer is re-unowned by production of neoplastic cells. In cancer, un-developed cells are produced by bone marrow. After their entry into the blood normal cells are un-able to produce and cause anemia. Several oncogenes, including the p53, c-fms and Ras genes, can be activated by point mutations that change the amino acid sequence in the critical portion of protein. L-asparaginase is an enzyme which, by hydrolysis, produces aspartic acid and ammonia. It is used as medicine and in the food industry. It acts as a chemo-therapeutic agent to diagnose the ALL and lymphoproliferative syndrome. The level of Asparagine reduced in plasma decreases the formation of Deoxy ribonucleic acid and Ribonucleic acid. In ALL, asparaginase used in chemotherapy medicines for dealing the patients. it donates the important development in therapy results and helps achieve reform sullener approximately 90% of patients.
Original Research Article
May 22, 2021
Phosphocalcic Status of Morocco Chronic Hemodialysis Patients and Adherence to Kidney Disease Improving Global Outcomes (KDIGO) Recommendations
S. Khlil, L. El Akkari, N. El Hammoumi, Z. Bennani, L. Balouche, Y. Bamou, F. El Boukhrissi
Page Numbers : 37-41
DOI : 10.36348/sijb.2021.v04i04.001
Introduction: Phospho-calcium balance disorders are very common in chronic hemodialysis. They are accompanied by a high risk of mortality, mainly due to cardiovascular complications. In this context, the KDIGO finalized recommendations updated to improve the quality of life of chronic hemodialysis and warn the complications which can engage the prognosis for survival. The objective of our study was to analyze the phosphocalcic status in Morocco chronic hemodialysis patients and to estimate the conformity of the results with the recommendations KDIGO. Materials and methods: This is a retrospective study over a period of 8 months from January to August 2018 which includes chronic hemodialysis patients followed at the laboratory of Biochemistry-Toxicology of the Moulay Ismail military hospital and the nephrology-hemodialysis clinic from Meknes. The biochemical parameters evaluated were determined on Cobas®6000 from Roche Diagnostics and then compared to the targets of the KDIGO recommendations. Results: A total of 86 patients were enrolled in the study. The average age of our patients was 44.86 ±12.65 years, with a sex ratio of 1.38. The percentages of patients with phosphocalcic data consistent with the KDIGO recommended targets for calcemia, phosphoremia and PTH1-84 were 75.5%, 50% and 43% respectively. Finally, 17.4% of patients met the KDIGO 2009 recommendations by combining all three criteria. Conclusion: The results obtained during this study should encourage clinicians to improve management of chronic hemodialysis patients.