Nutritional anaemia in pregnant women continues to be one of the major public health challenges. Anaemia contributes to one fifth of the maternal deaths and large number of preterm deliveries and low birth weight babies in India. The objective is to study the prevalence, various epidemiological factors, clinical presentation in pregnancies complicated with iron deficiency anaemia in a tertiary care teaching hospital in central India. A Prospective observational study was conducted for a period of two years from September 2012 to August 2014. A total of 1644 pregnant women were investigated for evidence of iron deficiency anaemia by performing haemoglobin estimation and peripheral blood smear examination. Information on epidemiological factors was collected through interview and information on clinical profile was collected in predesigned and pretested structured proforma. Statistical analysis was done by finding out percentages, proportions, Mean and Standard deviation (SD), Chi square test. It is found that the prevalence of anaemia among pregnant women was 49.40%. Mild, moderate and severe degree of anaemia was seen in 19.46%, 25.06% and 04.86% cases respectively. Prevalence of anaemia was more in women with early marriages and teenage pregnancies, women without antenatal care, who had not taken iron folic acid tablets, who were less educated and who belonged to families with low per capita income, from rural area and those who were grand multi-gravida with short inter-conceptional period of less than 24 months in regards to the index pregnancy. The study revealed high prevalence of iron deficiency anemia among rural pregnant population. Improvement in female literacy, health education, prevention of early marriages and teenage pregnancies, strengthening the peripheral health care delivery system , improving contraceptive use and provision of safe abortion facilities to control unregulated fertility can reduce the prevalence of anaemia in pregnancy

Corneal blindness account for 20 to 30 % of all blindness in the developing countries of the world. Corneal blindness is a major public health problem in India and infections constitute the most predominant cause. Various etiological factors have been observed in corneal blindness and factors associated with it. To study incidence of infectious keratitis and factors associated with it. All the patients of suspected of infectious keratitis were enrolled in the study. The detail of these patients such as age, sex and other demographic detail were entered in a prestructured Performa. In results the incidence of infectious keratitis amongst the ocular injuries was 63%.majority 37%of patients between 41 to 60 yrs of age .Males were affected more than females. Agricultural injuries & occupational accidents were most common cause if infectious keratitis. In conclusion the Trauma was found to be the most important predisposing factor for both bacterial and fungal keratitis and was found 63 patients in bacterial ulcer (58.97%) cases were because of trauma in fungal corneal ulcer (83.87%) were attributed to trauma

We present a patient exposed to minocycline for 3 years for treatment of resacea, presenting with disfiguring buccal mucosa hyper pigmentation. Discontinuation of the minocycline resulted in dramatic improvement documented in the serial images.

The effect of myeloid leukemia therapy has been widely noticed especially in acute myeloid leukemia mainly of liver enzymes. The objective of this study was to estimate the concentrations of some liver biochemical parameters (enzymes and proteins) including total protein, albumin, globulins, AST, ALT, ALP, and GGT, as well as to study correlation between these parameters in myeloid leukemia patients. This is a cross-sectionalstudy conducted in Institute of Nuclear Medicine and Oncology in Wad Madani City, Gezira Stateduringthe period from October to November 2015. The blood samples were obtained from 110 patients, 60 newly diagnosed myeloid leukemia with nottreated yet, and 50 patients treated with chemotherapy, all biochemical parameters were assessed using reagent kits, spectrophotometric method (BioSystem, Spain-Bercelona) was used. The mean of AST, ALT, GGT showed statistical significant increase, p. values (0.01,0.005, 0.026, 0.04), respectively compared to reference values.Mean levels of AST, ALT were higher in pretreatment <20years when compared with post-treatment <20 years, p.values (0.008, 0.025), respectively, as well as in pre and post treatment >20 years group also they observed significance values (0.000, 0.001), respectively. ALP enzyme level was significantly elevated in only the post treatment >20 years group, p.value (0.03). Pearson's correlationsbetween (age/disease, AST/ALT, AST/ALP, ALT/ALP) of the pretreatment group was found significant positiver. values (0.438, 0.886, 0.540, 0.492) p.value (0.000), while in post treatment group r.values were (0.272, 0.511, 0.960, 0.512), respectively and p.value for each (0.000). This study revealed that, thechemotherapy of myeloid leukemia in patients causes significant change in serum liver enzymes AST, ALT and GGT. There was a positive correlation between the myeloid leukemia disease and elevation of liver enzymes of pre and post treatment patients groups