The article presents the results of experimental studies, during a 3-month period of time, devoted to the chronic toxicity research of the first synthesized compound – 7-(3-chlorobutylene-2-yl-1)-8-N-methylpiperazino-3- methylxanthine (chlomepiroxane), possessing anthelmintic activity.

The objective of this study was to establish weight estimation equations from body measurements applicable to Lagune cattle. Live weight (LW), body length (BL), heart girth (HG), and withers height (WH) were recorded in 909 Lagune cattle (506 males and 403 females) aged from 0 to 45 months at the Samiondji Breeding Farm in southern Benin. The correlation of weight with the BL (males - 0.95, females - 0.80) or with the HG (males - 0.96, females - 0.97) was higher than with the WH (males - 0.92, females - 0.79). Several types of equations between the weight and the three body measurements were compared. The equations retained for the Lagune cattle were polynomial regressions of the predicted weight (Y) on the BL (x), the HG (z) and the WH (t): Y = -77.29 - 0.07x + 1.47z + 0.18t for males and Y = -1.31 + 1.74x + 1.77z - 1.99t for females. The coefficients of determination R2 were 0.95 and 0.94 for the respective males and females, while the Mallows coefficients were identical Cp = 4.00. The residual means of differences between observed and predicted weight were small (2.6 vs. 4.2 kg for the respective males and females) indicating good accuracy of the estimates.

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems. WHO estimates traditional medicines, mostly plant drugs cater to the health needs of nearly 80% of world population. The aim was to study the influence of Trigonella foenum-graecum seed powder on the basic parameters of obesity induced by hight calorie diet. We included 40 male rats and divided them to 4 groups of 10 animals in each group. Normal rats (groups 1, 3) were fed by a standard chow, while the others (groups 1, 4) were fed with high-caloric diet during 14 weeks. From week 15 to 18, groups 2 and 4 were treated with Trigonella foenum-graecum seed powder (Fg). Liver function markers were estimated by biochemical analyzer Microlab 300 and commercial kits from Elitech diagnostic according to the standard protocols provided by manufacturers. The serotonin content was determined in brain using ion-exchange chromatography and fluorescence methods. We have shown that consumption of high-calorie diet leads to changes in food behavior and the development of obesity in rats. Treatment of obese rats with Trigonella foenum-graecum seed powder leads to normalisation of key physiological and biochemical parameters. Treatment with Fg significantly suppressed the increments of body weight, fat weight. Fg improved lipid levels. These results demonstrated the treatment effect of Trigonella foenum-graecum seed powder on the basic parameters of obesity induced by hight calorie diet.

Plants form the main ingredients of medicine in traditional system of healing and have been the source of inspiration for several major pharmaceutical drugs. In spite of great advances of modern scientific medicine, there is a rapid increase in the use of alternative medicine worldwide. To investigate the effect of the aqueous root extract, Methanol and n-Hexane root fractions of Curcuma longa Linn on Alloxan Induced Diabetic Rats. A total of thirty-six (36) rats were used and were grouped into six (6) groups of six (6) rats each. Group I served as normal control, group II served as diabetic control, Group III rats were induced with diabetes and administered with standard drug (Metformin, 100mg/kg) while Groups IV, V and VI were induced with diabetes and administered with crude aqueous extract, methanol and n-hexane fractions respectively at a dose of 400mg/kg body weight for four weeks. The research found that the methanol fraction showed highest potency with a significant (p<0.05) decrease in blood glucose level when compared to diabetic control after few days of fraction administration, it was followed by the aqueous extract which also shows hypoglycemic activity a week after administration. N-hexane fraction showed a marked hypoglycemic activity only after about two weeks of administration with the fraction. The present study demonstrated that the methanol fraction possesses the highest hypoglycemic activity.

The demonstration was carried out at the farmers’ fields of Barisal region of Bangladesh to evaluate the effectiveness of fertilizer application methods in T. Aman rice in non-saline tidal flooded soil during July to December, 2015. Twenty-five-day old seedlings of BRRI dhan52 was transplanted in randomized complete block design with three replications. The trial was conducted in five locations (Babuganj, Barisal; Nolchiti, Jhalokathi; Barisal Sadar, Barisal; Amtoli, Barguna and Kolapara, Patuakha). Deep placement of urea super granule (USG) (1.8 g size) + PKSZn from BRRI recommended dose was compared with BRRI recommended fertilizer dose and farmers’ fertilizer management. The result showed that USG treated plots produced statistically the highest grain yield and less spikelet sterility compared with BRRI recommended fertilizer dose and farmers’ practices at all locations. Also, panicles per unit area and grains per panicle were highest in USG treated plot than broadcasted urea. Thus, the results revealed that USG application is the best N source in non-saline tidal ecosystem of Barisal region in T. Aman rice.

The Neurosyphilis is the most severe neurological complication of the active syphilis. It puts real diagnostic problems because of the ascendancy of the atypical forms. Our objective is to analyze the clinical symptoms and to assess the relevance of the different laboratory findings in cerebrospinal fluid (CSF) and serum for the diagnosis and survey of active neurosyphilis. A retrospective study of six hospitalized neurosyphilitic patients at Hospital Moulay Ismail of Meknès from 2003 to 2015 was carried out. Neurosyphilis can be grouped in two categories: early (meningeal and meningovascular neurosyphilis) and late (progressive general paralysis and tabes dorsalis). All patients are HIV negative. All the patients are benefited for an examination cytochimique of the CSF and an examination immunological with the tests VDRL and TPHA for the search for the specific antibodies in the CFS and the serum. The CSF anomalies in neurosyphilis included elevated cell count with lymphocytic-plasmocytic cell reaction, increased protein content, strongly positive blood and CSF serology.