Saudi Journal of Biomedical Research (SJBR) | Volume-5-Issue-09
Original Research Article
Sept. 13, 2020
Prevalence of Mental Disorders and the Pandemic of COVID-19: A Contemporary Literature Review
Amal Ibrahim Khalil
Page Numbers : 249-254
DOI : 10.36348/sjbr.2020.v05i09.001
Background: The association between COVID-19 and mental illness started due to the inevitable fear and anxiety about the emergence of a new disease. A future so unpredictable can be overwhelming and can cause strong emotions not only in adults, but also in children. Aim: The present review aimed at collecting and corroborating the contemporary literature on the prevalence of mental illnesses symptoms and therapeutics interventions relevant to the pandemic of COVID-19. Methods: To compile this review a search of the PubMed electronic database was undertaken using the search keywords such as “novel coronavirus”, “COVID-19”, “history “prevalence of mental illnesses”, “anxiety”, “depression” and “post trauma stress” in various transformations and groupings. In addition, search was done about the availability and barriers of psychiatric, psychological and therapeutics interventions related to mental health problems in caused by the pandemics of Covid19. Conclusion: Despite the limited numbers of observational studies in this field to date, it is obvious that, the COVID-19 pandemic has Covid-19 has been a wakeup call to to a forceful and multidimensional response from psychiatrists and allied health professionals, that mental health of people during pandemics should be taken seriously at multiple levels of primary ,secondary and tertiary prevention Therefore, more work needs to be directed toward the development of community health professionals specialists, qualified to address emotional distress and identifying the basic aspect of mental health interventions Further, there is a need to develop mental health interventions which are time-limited, culturally sensitive, and can be taught to healthcare workers and volunteers to be widely disseminated among those working in this field during the pandemics.
Original Research Article
Sept. 17, 2020
Chemoprevention of Chemical Carcinogenesis Induced Colon Tumor in Experimental Animals by Nonsteroidal Anti-Inflammatory Drugs and Compare with Special Stains in Histopathology
Saeed Mahmoud Saeed Mohamed, Afaf Mosaad Amin, Suzanne William Skander, Aisha Mohmmed Osman salih, Marwan Mustafa Badawi, Mahmoud Assem Hamed
Page Numbers : 255-263
DOI : 10.36348/sjbr.2020.v05i09.002
Colorectal cancer (CRC) is among the most common types of cancer in the world. Globally a steadily increasing proportion of elderly people in the world result in approximately 16 million new cases of cancer by the year 2020. Regarding treatment; Meloxicam was shown to prevent the initiation of chemical-induced tumors, and considered as anticancer agent by virtue of its anti-proliferative effect, capacity for cell cycle arrest, and pro-apoptotic effects, also acted as free radical scavenger, in particular superoxide anion oxidation scavenge. The aim of the current study was to investigate the protective role of meloxicam against colon cancer. The study was carried out on 60 male albino rats, animals were divided into 5 groups; A: control group, B: animals received S.C. injections of 20 mg 1,2 DMH /Kg b.w, C: animals received 1, 2 DMH with ad libitum access to water and high fat diet, D: animals fed high fat diet and water ad libitum. E: animals received S.C. injections of 1,2 DMH and oral 15mg/Kg /day meloxicam/0.1 ml saline. Colon tissues from all studied groups were stained applying the following techniques: Hematoxylin & eosin, Alcian blue pH 2.5- acid mucopolysaccharide, Feulgen nuclear staining of DNA, Whole mount staining of colon. The results confirmed the efficacy of meloxicam inhibiting or delaying growth of aberrant crypt foci in colon. Further research is needed to support presented findings.
Sept. 17, 2020
Simultaneous Moderation Effect of Industry Forces and Firm Resources on Entrepreneurial Orientation: A Case Study of Small Size Hotels in Ghana
Adelaide Spio-Kwofie, Ivy Fosua Osei, Sharon Atakpa, Eric Paintsil
Page Numbers : 264-276
DOI : 10.36348/sjbr.2020.v05i09.003
This study has attempted to answer the impact of entrepreneurial orientation on business performance of small hotels in Ghana; the moderating effect of industry forces and firms’ resource. Like any other empirical related study, four constructs, namely entrepreneurial orientation, industry forces, firms' resources, and business performance were used. The study adopted a survey research design that involves the use of quantitative sampling techniques for the primary data. A sample size of three hundred and ninety-six (396) owner-managers was emailed with a questionnaire to solicit for their responses. Analysis of the independent dimensions of entrepreneurial orientation showed significant correlations between each of the variables and hotel performance. The strategic use of firms’ resource revealed that it positively moderates the relationship between entrepreneurial orientation and business performance. Although the hotel industry is turbulent, the strategic implementation of firms’ resources neutralizes the strength of industry forces on the business performance. Again, strategic implementation of these resources increases business profitability, sales growth, customer retention, and customer satisfaction. The findings of this research contribute both to small business management and measurement theory, as well as providing a basis to guide small business policymakers, educators of hospitality management and hotel managers in general.
Original Research Article
Sept. 28, 2020
Staining of Thin Peripheral Blood Smear with Modified Methanolic Extract of Hibiscus sabdariffa Calyx
Emmanuel Asuquo Etim, Oziegbe Johnson Airen
Page Numbers : 277-281
DOI : 10.36348/sjbr.2020.v05i09.004
Background/Objective: Methanolic extract of Hibiscus sabdariffa extract usually produces a brilliant reddish liquid and it is believed that modification of this colored liquid may have good staining effect on thin blood smear. Therefore, this study aims to examine the staining effect of modified methanolic extract of Hibiscus sabdariffa calyx on thin peripheral blood smear in other to obtain surrogates hematological stains. Materials and methods: Dried calyx of Hibiscus sabdariffa was obtained commercially from Yola. The calyces were pulverized to fine powder and 10g of the powder was soaked in 50ml of absolute methanol for 12hours to obtain methanolic extract and thereafter, equal volume of both methanolic extract and methylene blue were mixed to obtain a modified methanolic extract. pH of modified extract was determined using pH meter. The modified methanolic extract was further used to stain thin peripheral blood smear. Results: Modified methanolic extract of Hibiscus sabdariffa calyx had pH of 7.1. The extract produces a poor staining effect on erythrocyte but gave a deep blue coloration on leucocytes, while the control stains such as field stain and Leishman stain produces a normal coloration on leucocytes and a dark pink coloration with normal pallor on erythrocyte. Conclusion: Modified methanolic extract of Hibiscus sabdariffa calyx has PH of 7.1 and produces a poor staining effect on erythrocyte but impacted a deep blue coloration on nuclear lobes of leucocytes microscopically. More research to get a modified concentration and a molar equilibrium of acidic and basic components in this extract is recommended.