Saudi Journal of Biomedical Research (SJBR) | Volume-5-Issue-03
Volume-5-Issue-03
Original Research Article
March 6, 2020
Acute Toxicity Study and Serum Lipids Profile of Pet-Ether Extract of Leave, Stem Bark and Root of Jatropha curcas in Wister Rats
Abdulmumin T.M, Abdulmumin Y, Ibrahim AM, Sarki S I and Murtala M
Page Numbers : 30-35
DOI : 10.36348/sjbr.2020.v05i03.001
This study was carried out to evaluate the toxicity and serum lipid profile of pet- ether leave, stem bark and root extract of jatropha curcas in male albino rats. Fourty-nine (49) adult wister rats weighing between 160-240mg/kg was purchased and 14 wister rats were used for acute toxicity study while the remaining 35 rats were randomly divided into 7 groups of 5 rats each. The normal control (group 1) received normal saline, while groups 2 to 7 administered with leave, stem bark and root extracts of jatropha curcas at low dosse (200 mg/kg body weight) and high doses (400 mg/kg body weight). The extracts were administered orally for seven consecutive days, while the animals were sacrificed on the 8th day; blood samples were collected, allowed to stand for fifteen minutes and then centrifuged to obtained the serum for lipid profile analysis. This result showed that the oral administration of the leave, stem bark and root extract of Jatropha Curcas possess hypolipidemic activity and may be useful in the management of cardiovascular disease. While acute toxicity (LD50) of the Leave, Stem Bark and Root Extract of Jatropha Curcas is greater than 5000mg/kg hence its declared practically non-toxic to the experimental animals.
Short Communication
March 6, 2020
Behaviors and Believes Against Coronavirus
Mosab Nouraldein Mohammed Hamad
Page Numbers : 36
DOI : 10.36348/sjbr.2020.v05i03.002
No Abstract
Review Article
March 8, 2020
Neonatal Jaundice
Yousif M Elhaj, Mosab Nouraldein Mohammed Hamad
Page Numbers : 37-38
DOI : 10.36348/sjbr.2020.v05i03.003
This review article discussed on neonatal jaundice which is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels Other clinical features may include excess sleepiness or loss of appetite. Consequences may include seizures, cerebral palsy. It may happen due to physiologic or pathologic etiologies. The need for treatment relies on bilirubin levels, the age of the child, and the underlying cause treatment may include more frequent feeding, phototherapy, or exchange transfusions.
Original Research Article
March 16, 2020
Assess the Knowledge, Attitude, and Practices about Biomedical Waste Management among Healthcare Personnel
Dr. Tamilselvi, Ms. Devanithya
Page Numbers : 39-40
DOI : 10.36348/sjbr.2020.v05i03.004
Background: The waste produced in the course of healthcare activities carries a higher potential for infection and injury than any other type of waste. Inadequate and inappropriate knowledge of handling of healthcare waste may have serious health consequences and a significant impact on the environment as well. Objective: The objective was to assess knowledge, attitude, and practices of doctors, nurses, laboratory technicians, and sanitary staff regarding biomedical waste management. Setting: The study was conducted among hospitals (bed capacity >1000) of Allahabad city. Participants: Medical personnel included were, nurses (15) and sanitary staff (15) conclusion: The importance of training regarding biomedical waste management needs emphasis; lack of proper and complete knowledge about biomedical waste management impacts practices of appropriate waste disposal.
Original Research Article
March 21, 2020
Cross-Sectional Study of Prevalence of Genu Varum in Children 6-10 Years of Age in Urhobo, Delta State, Southern Nigeria
Peter D. Okoh, John N. Paul, Emmanuel Tobore
Page Numbers : 41-45
DOI : 10.36348/sjbr.2020.v05i03.005
Background: Genu varum (bow leg) is a deformity of the knee marked by medial angulations of the leg in relation to the thigh, an outward bowing of the legs, giving the appearance of a bow. This study was carried out to determine the prevalence of genu varum among children between 6-10 years old in some Urhobo communities in Delta state, Southern Nigeria. Materials and Methods: The study populations were drawn by purposive sampling from Ughelli, Warri, and Sapele. Data were collected on 1000 children (500 males and 500 females). Physical examination of the children was carried out by measuring their medial intercondylar distances by using calipers and meter rule while the children stood erect with their ankles touching. Children with medial intercondylar distances greater than 0.2cm (the mean value for normal Nigeria children) demonstrates the deformity (genu varum) and the frequency, age. sex was recorded. Results and Discussions: Based on this data, 43 in 1000 volunteers had genu varum. It was also seen that the prevalence was highest in 6 years old age group and lowest in 10 years old age group. It was noted as the ages increase, the prevalence rates among the age groups decreases. The prevalence of this deformity in Urhobo communities is low when compared with the overall prevalence in Nigeria. The Urhobos live in the riverine area of Southern Nigeria and their occupation are mainly farming, hunting and fishing. Their meals consists mainly of products from the farm, hunting and sea foods which are very rich in protein/calcium. Children in Urhobo Communities are also well exposed to sunlight. Conclusion: The prevalence of this genu varum in this ethnic nationality although low can be further reduced with enlightenment and education of parents and children on the importance of balanced diet.
Review Article
March 30, 2020
Minocycline Superior to Chloroquine Phosphate as COVID-19 Treatment
Mosab Nouraldein Mohammed Hamad
Page Numbers : 46-47
DOI : 10.36348/sjbr.2020.v05i03.006
COVID-19 infection is the current challenge that faces the research community worldwide. Although chloroquine phosphate, an old drug for management of malaria, revealed to have clear value and tolerable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China, we theorize that minocycline combined with suitable non-steroidal anti-inflammatory drug will give better result than Chloroquine phosphate monotherapy. Nouraldein theory needs invitro and Invivo experiments to confirm it.
