ORIGINAL RESEARCH ARTICLE | Jan. 25, 2020
Cerebrospinal Fluid Glutamic Oxaloacetic Transaminase and Lactate Dehydrogenase Levels in Alzheimer’s disease
Subhramay Chatterjee, Sandip Chakraborti
Page no 6-8
Glutamic oxaloacetic transaminase and lactate dehydrogenase are present in brain. The present study was undertaken to investigate whether there was any change in cerebrospinal fluid glutamic oxaloacetic transaminase and/or lactate dehydrogenase levels in Alzheimer's disease. In the present case control study cerebrospinal fluid glutamic oxaloacetic transaminase and lactate dehydrogenase levels were assayed in 162 Alzheimer's disease cases and 149 healthy controls. Glutamic oxaloacetic transaminase levels of cases were highly significantly increased with respect to the levels of controls. Lactate dehydrogenase levels of cases were not significantly increased with respect to the levels of controls. Data from the present study might help in understanding the biochemical basis of Alzheimer’s disease. It is stressed that these findings should be supplemented by further prospective research.
ORIGINAL RESEARCH ARTICLE | Jan. 14, 2020
Effect of Human Papilloma Virus Type 16 and 18 infections on Young Married Women Aged 18-24 Years in River Nile State 2017
Abd alwahab Jahalnabi Jubara Bakheet, Mosab Nouraldein Mohammed Hamad, Mohammed Ahmed Ibrahim Holie
Page no 1-5
The study was done in river Nile state, from September to November 2017. The research applied on 50 urine samples which collected from married ladies with young ages (18-24 years) unvaccinated against Human Papilloma Virus 16 and 18 that known as high risk viruses to detect DNA of it and probability of it to cause cervical cancer. The study aimed to detect affection of high risk HPV type 16 or 18 on young married ladies (16-18 years)an vaccinated against it Then probability to cause cervical cancer. Used molecular method to detect presence of high risk HPV DNA (16or 18) in urine sample which collected from the study group. All 50 samples were negative, that mean no detection for HPV16 or 18 DNA.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2020
Assessment of Seminal Plasma Trace Elements among Infertile Sudanese Males in Khartoum State, 2019
Mutaz Ibrahim Hassan, Abdelrhman Mohamed Sid Ahmed, Mosab Nouraldein Mohammed Hamad, Gamal Mahmoud Elimairy
Page no 9-13
Background: Male infertility is a multifaceted state and overlaps a lot of factors and affects infertility in about 8–5 % of the people in the world and the man is responsible for 40% of these cases. Dietary insufficiency of trace element, zinc and copper may play a role in male infertility as trace element plays an important role not only in normal testicular improvement, but also in spermatogenesis and sperm motility. Objective: The current study was intended to analyze the level of seminal plasma trace elements mainly zinc and copper amongst dissimilar groups of infertile men. Method: The concentrations of zinc and copper were measured in 160 semen samples from normozoospermic, oligoathenospermic, and azoospermic men using the atomic absorption spectroscopy, data was analyzed using the statistical software package SPSS version 17. Result: Outcomes showed that the mean values of seminal plasma zinc concentrations were significantly decreased in the two groups of infertile male subjects, azoospermic (P.value=0.000), and oligozoospermic (P.value=0.013) compared with fertile males, while there was significant decrease in seminal plasma copper concentration of azoospermic patients compared to control (P.value=0.000), and significant decrease in oligozoospermic patients compared to control (P.value=0.000).