Vitamin D plays a role with hormones in their receptor sites. Without vitamin D, hormones cannot function the way they would normally. The receptor sites malfunction, leaving estrogen, progesterone, testosterone, luteinizing hormone, and follicle stimulating hormone in the lurch. Without healthy action at receptor sites, hormones don’t get utilized. The menstrual cycle fails as a result PCOS results. There is no published data about the relationship between vitamin D deficiency and polycystic ovaries syndrome among Sudanese ladies with infertility disorders. To know the association between vitamin D deficiency and polycystic ovaries syndrome among Sudanese ladies with infertility disorders. Descriptive, cross-sectional study, 39 Sudanese ladies with known PCOS and infertility disorders were involved in the study. 71.8% of ladies with polycystic ovaries syndrome were vitamin D deficient. Further studies must be carried out, using large sample size and more than one diagnostic technique.

The aim of this research is to know the effectiveness of drinking of mung bean on the increase of Hemoglobin in female adolescents in Paguyaman District. Research type pre-experiment with one group pretest-posttest design. Sample in this research is done with total sampling. The result of the statistical test and the onesample test results obtained p = 0.000 is known that there is a significant difference between pretest and posttest group, therefore the significant value is less than 5% (p = 0.000 <0.05) so that in this case there is effectiveness of giving mung bean drink with hemoglobin increase in adolescent girls in Paguyaman District. This research can be used as input to improve healthy lifestyle and give special attention intake of nutrition consumed by adolescent itself.

H pylori infection is well known to be the most common human infection worldwide on the basis of the fact that approximately 50% of the worldwide populations are infected and that human beings are the main reservoir. Infection is more prevalent in developing countries, and incidence is decreasing in Western countries. Moreover, it has been proved to be associated to endocrine system regulation of various hormones in the body, prolactin (PRL) is one of the reproductive hormones, which is secreted by the anterior pituitary gland. The biological actions of prolactin hormone are Lactotrophic effects, metabolic effects influence to action of other hormones, osmoregulatory effects, and Influence of prolactin on the immunological system. This study was conducted in Khartoum State at the period from December 2015 to May 2016, and aimed to determine the possible effect of H. pylori infection on serum prolactin levels in Child-bearing females age (15 – 45). Sample size was 50 females infected with H. pylori and 50 uninfected females as control group. Stool Samples were taken from the entire study subject (100) samples to confirm the results of H. pylori Ab ICT in serum. The stool samples were analyzed by using H.pylori stool Ags detections ICT. Serum prolactin level was measured by using Cobas e411chemistry analyzer, the results showed that Prolactin concentration was higher in the patients compared with controls. In this study hyperprolactinemia due to H.pylori infection was reported in 52% of the patients. Statistical analysis showed that there was significant difference in the mean of prolactin concentration between infected and uninfected females group (P= 0.000). Regarding correlation between prolactin concentration and subject’s age, H. pylori infection duration or recurrence of infection, no significant was found to be observed.

Periodontitis are multifactorial infections that begin with a period of inflammation of the supporting tissues of the teeth and then progress destroying the tissues until loss of the teeth. The goal of periodontal treatment is to stop the progression of the disease, restore functions and regenerate the damaged tissue. However, regeneration of different tissues, by conventional treatments, still remains great challenge. To address this, there are several approaches to tissue engineering for regenerative dentistry, among them, the use of stem cells by including dental pulp stem cells (DPSCS), periodontal ligament stem cells (PDLSCS), stem cells from the dental apical papilla (SCAPS), stem cells from human exfoliated deciduous teeth (SHEDS), dental follicle stem cells (DFSCS), dental epithelial stem cells (DESCS), bone marrow mesenchymal stem cells (BMMSCS), adipose-derived stem cells (ADSCS), embryonicstem cells (ESCS) and induced pluripotent stem cells (IPSCS). This novel approach may represent an effective therapeutic tool for periodontal regeneration. However, there are still obscurities regarding the mechanisms underlying in periodontal regeneration and challenges in applications of dental stem cell. Further efforts are necessary before moving to clinical trials for future applications.

Despite widespread use, little is known about the risk associated with insecticides exposure to human health hence, this study. 48 wistar rats (90-120g) were randomly grouped into six (n=8). All except Normal control (NC) were exposed to domestic insecticide fumes once every 48 hours. Group 2, insecticide control (IC) was exposed to (20% of 81.55mg/m3) 0.20mg/ml of DAKSH insecticide. Group 3, positive control (PC) was treated with a standard testosterone drug-Nugenix. Groups 4, 5 and 6 received 400mg/kg b.w each of crude extract (CE), ethylacetate and n-hexane fractions of Vernonia calvaona (VC) daily via orogastric intubation for 21 days. After administration, animal sacrifice and blood collection was done via cardiac puncture for analysis. The result presented a significant decrease (p<0.05) in testosterone of IC group compared to NC. Groups 3 and all treated groups effected progressive increase in testosterone concentration compared to IC group. FSH was significantly reduced (p>0.05) in IC and n-hexane fraction of VC compared to control. However, nugenix treated and ethylacetate fraction caused a remarkable increase in FSH compared to IC. WBC was significantly decreased (p<0.05) in IC and n-hexane groups compared to control. The Crude Extract treated group significantly increased WBC count compared to IC group. Histopathological studies of the testes showed varied levels of histological derangements in IC while Ethyl acetate treated group showed highest regenerative ability. This study revealed that insecticides adversely affected male gonads while the extracts showed ameliorative effects with the highest effect seen in ethyl acetate fraction in managing the insecticide induced damage.

Wounds are a significant cause of morbidity worldwide, studies show that for every million wound patients, at least 10.000 die from microbial infections. The skin is a vital organ that serves as a protective barrier between the human bodies on its external environment. Staphylococcus aureus has been known as a cause of deepseated wound infection for close to a century, having recognized as a cause of nosocomial infection and super infection in patients receiving antimicrobial agent such as surgical cases. MRSA colonizing the anterior nares and skin of human are the major sources of surgical site infection as well as nosocomial spread. Methicillin-resistant Staphylococcus aureus (MRSA) are bacteria resistant to penicillin and cephalosporin classes of antibiotics and are often resistant to many other classes of antibiotics. Importance of S. aureus as persistent nosocomial and community acquired pathogen has become a global health concern. The aim of this study to determine the frequency and antibiotic susceptibility pattern of S.aureus isolated from wound infected patient attending Wad Madani Teaching Hospitals. Two hundred samples collected from patients with infected wound at the period from April to July 2016. Out of 200 samples examined, 60 (30%) isolates of S. aureus obtained, 116 (58%) other bacterial species and 24 (12%) samples showed no growth. The highest isolation rate of S. aureus 60% occurred among age group (41-60) and according to gender 32 (53.3%) S. aureus isolated from male and 28 (46.7%) from female. The overall profile of susceptibility pattern showed that vancomycin and linezolid were more sensitive (100%), amoxicillin and penicillin were the least sensitive (10%) and (36%) respectively. The result of the study showed that frequency of S. aureus isolated from infected wounds 60 (30%) and vancomycin and linezolid are more effective in the management of S. aureus in this locality.

Majority of the drugs used for the treatment of various diseases are administered by oral route using conventional delivery. The major drawback of the oral administration is the poor bioavailability due to the poor water solubility, chemical stability and pre-systemic metabolism. Numerous researches are going on for the improvement of oral bioavailability of drugs using novel drug delivery systems as an alternative to conventional delivery systems. Majority of the novel delivery system includes; solid dispersion, sustained, controlled buccal, gastro retentive, nano carrier delivery systems such as lipid nanoparticles, and self-emulsifying systems. The oral bioavailability improvement by these delivery systems might be due to the increased particle size, improved dissolution and/or permeation and subsequently bioavailability of the drugs. In this review, we attempt to discuss the various novel delivery systems developed for the enhancement of oral bioavailability of poorly water soluble therapeutics.

Lip prints are normal lines and fissures in the forms of wrinkles and grooves present in the zone of transition of human lip, between the inner labial mucosa and outer skin. Examination of this lip prints is known as cheiloscopy. Some authors have worked on lip print in the past and made some striking points on its application in forensic studies and human identification. The study was carried out to identify and compare the lip prints patterns among the Igbos. The study was done to investigate and document the characteristic cheiloscopic pattern of Igbos and to assess the distribution of lip print patterns among males and females. A total of 300 subjects were used for the study. 150 were males, 150 were females, all of which were normal subjects. Subjects were selected and identified based on an oral interview. These subjects were selected through purposive convenient sampling method. The males and females had their highest percentage distribution in type I (35.73%) and (30.53%) respectively; the least percentage was in type IV (9.33 %) for the males and type I’ (7.80%) for the females. this study has been able to establish the cheiloscopic patterns for the Igbo ethnic group in Nigeria. The dominant pattern of the population was type I followed by type II and the least was type I’. It also revealed sexual dimorphism in the patterns and frequency of distribution of lip prints.