Unani system of medicine is based on the theory of Mizaj and Akhlat which is considered as the basics of Unani therapeutics. Mizaj is defined as the admixture of four humours (Akhlat), the quantity and quality of which determines the particular Mizaj of an individual. Every individual has its own unique Mizaj (temperament), hence reacts to various internal and external stimuli viz.air, water, diet, drug, climate, emotions, body reactions etc. differently according to temperament. Hence, Mizaj plays an important role in diagnosis and treatment of any disease. Since, Hypothyroidism is considered as one of the most common endocrine disorders in which patient has somnolence, fatigue, cold intolerance, constipation, loss of libido, gain in weight etc. According to the classical texts of Unani Medicine, it is the concentration, quality and quantity of humours which forms the base and cause of health and disease in an individual. As per Unani doctrine, Mar’d (Disease) is caused either due to Su’ Mizaj (abnormal temperament), Su’tarkib( abnormal composition/structure) or Taffaruk Ittesal (discontinuity).This study was conducted at Regional Research Institute of Unani Medicine, University of Kashmir ,Srinagar Jammu & Kashmir to evaluate the Mizaj (Temperament) of patients of Hypothyroidism. Out of 60 patients enrolled for the study, 52 (86.6%) were Balghami, 03 (5%) were Damwi, 05 (8.3%) were Safravi and none was of Sawdawi Mizaj. Thus, it was evident that Hypothyroidism is more common in Balghami Mizaj patients.

Medicinal plants play a vital role to preserve human health. The genus Argemone consists of herbs, that are widespread in all over India and represents highly valuable plant species having therapeutic and nutraceutical importance. Genetic variation is essential for long term survival of species and it is a critical feature in conservation. Argemone mexicana (Papaveraceae) also known as Ghamoya. Traditionally the plants used the world for the treatment of several ailments including tumors, warts, skin diseases, inflammations, rheumatism, jaundice, leprosy, microbial infections, and malaria. It is an exotic weed indigenous to South America. In the present study an attempt has been made to assess the preliminary phytochemical screening and TLC profile of various leaves extract of A.mexicana.