ORIGINAL RESEARCH ARTICLE | Dec. 10, 2021
Prevalence and Clinical Correlates of Pulmonary Hypertension in Systemic Sclerosis
Rezwanuzzaman SM, Al Miraj AK, Mony SK, Zaher MA, Ullah MA
Page no 186-191
Introduction: Development of pulmonary artery hypertension (PAH) worsens prognosis of systemic sclerosis (SSc) and can be either isolated precapillary PAH or secondary to interstitial lung disease (ILD). Early diagnosis is of crucial importance. There is scarcity of data on PAH in patients with SSc in Bangladesh. Objectives: To determine the Prevalence and clinical correlates of pulmonary hypertension in systemic sclerosis. Materials and Methods: The concerned non randomized cross-sectional observational study was conducted at department of Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka, Bangladesh. Clinical and functional characteristics of 100 patients of systemic sclerosis were studied and they were evaluated by echocardiography to detect pulmonary artery hypertension. Our objective was to study the prevalence and the clinical correlation of PAH in SSc. Results: PAH was found in 29% patients on echocardiography. Prevalence tend to increase with age of onset and duration of disease. However, it did not differ significantly between patients with limited cutaneous SSc (lcSSc) and patients with diffuse cutaneous SSc (dcSSc). On binary logistic regression analysis, none of the studied variables had any independent influence on development of PAH. Conclusion: PAH in SSc occurs in a remarkable proportion (29%) of patients without any ominous signs in early stages. Non-invasive screening of patients with SSc for PAH will help in early diagnosis and appropriate timely therapeutic intervention before significant end-organ damage occurs.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2021
Epidemioclinical Study of Cervical Cancer Screening by Visual Tests at the Hospital in Mali Bamako
S. Mariko, N. Doumbia, S. Sogoba, M. B. Coulibaly, A. Traore, A. Togo, A. Saye, P. Coulibaly
Page no 192-198
Introduction: Mortality from cervical cancer remains very high in Mali. The insufficient early detection of cervical cancer means that this disease still kills many women in our country and is a public health problem at the cost. The objective was to determine the place of visual tests, visual inspection after application of acetic acid (IVA) and lugol solution (IVL) in the context of the prevention and fight against cervical cancer at the level of the service. of gynecology at the Mali hospital in Bamako. Material and Methods: We carried out an exhaustive descriptive retrospective study over three (3) years between 2018 and 2019, including 2351 women who participated in the voluntary and free screening of precancerous lesions of the cervix at the level of the gynecology department at the Mali hospital. Results: IVA was positive in 4.8% of cases versus IVL positive in 5.2% of cases. The mean age of women was 38.66 ± 9.83 years. Out-of-school women were the most affected by the disease 80% of cases. The frequency of low-grade dysplasia, moderate dysplasia and high-grade dysplasia was 1.5%, respectively; 1.4%; 1.3%. The overall frequency of precancerous cervical lesions was 4.2%. Conclusion: Early detection of cervical cancer by IVA / IVL visual tests is an effective means of preventing and combating cervical cancer. Awareness should be intensified among the illiterate rural population in order to minimize the incidence of this disease in our country.