REVIEW ARTICLE | Jan. 14, 2020
Efficacy of Kumari [Alove Vera (L)] on Agnidagdha Vrana (Burn Wound) With Special Reference to Ayurvedic and Modern Aspect: A Review
Dr. Pansare TA, Sole AP
Page no 1-11
Nature has gifted numerous plants to mankind for prevention and management of diseases. Kumari [ALOVE VERA (L.)] belonging to Family Liliaceae is traditionally advocated by the IndianAyurvedic medicine to treat a huge variety of health problems. Its burn wound (Agnidagdha vrana) healing action has been mentioned in Ayurvedic classics viz. Kaiyadev Nighantu, Bhavprakash Nighantu and Shaligram Nighantu. According to Ayurveda, due to its Dahaprashman (cooling), Rasayana (rejuvenating), Vishaghna (anti-toxic), Balya (strength providing) actions and Kledashodhan (removes kleda) acions, it helps in burn wound healing. This plant contains Lupeol, salicylic acid, Anthraquinones, Glycoproteins, Polysaccharides etc. which are accountable for speedy wound healing. It is endowed with varied pharmacologicalactivities like antiseptic, anti-inflammatory, immune-modulatory, analgesic, anti-bacterial, moisturizing and cooling and anti-oxidant that aid wound healing.This plant has potential to cure sunburns, burns and minor cuts, and even skin cancer. The present review compiles information on Ayurvedic aspect as well as phytoconstituents and relevant pharmacological studies of Kumari regarding burn wound (Agnidagdha vrana) healing action. The present data is an endeavour to give scientific justification to the acclaimed activity i.e. its burn wound healing potential (Agnidagdhavranapaha) as stated in Ayurveda. It provides encouragement to investigators for conducting further research in order to develop an efficient and safe innovative chemical entity for the cure of burn wound.
ORIGINAL RESEARCH ARTICLE | Jan. 27, 2020
Anti-Inflammatory and Central Analgesic Effect of the Aqueous Extract of the Leaves of Vitex Madiensis Oliv (Lamiaceae-Viticoïdeae)
Nsonde Ntandou GF, Dianzitoukoulou Matsima L.D., Ingabire J, Makemba Nkounkou GS, Nkundineza JC, ABENA AA
Page no 12-17
Vitex madiensis Oliv is a plant of the family of the Lamaceae-Viticoideae used in traditional medecine in Congo against: dysenteriform diarrheas, barreness of the women, madness, otitis, tooth decay, oral affections, malaria, inflammation of ganglia and stiffness. The aqueous extract of leaves of Vitex madiensis oliv. was the subject of an investigating by the carraghenine and the histamine induced inflammation, and on the central pain of thermal origin at the doses of 50, 100, 200 and 400 mg/kg per os. A significant anti-inflammatory effect (***p< 0,001) at the dose of 400 mg/kg from the thirst hour and at the dose of 200 mg/kg from 3hours was observed. A significant (***p< 0,001) analgesic effect was observed at the dose of 400 mg/kg from 30 minutes. These effects are due to the presence of the numerous metabolites contained in this extract.