Psoriasis is a common chronic, recurrent, immune mediated disease of the skin and joints. It can have a significant negative impact on the physical, emotional and psychosocial wellbeing of affected patients. Many Ayurvedic texts have explained skin diseases, which resembles Psoriasis. According these references, Psoriasis can be considered as the vitiation of Vata and Kapha. The “wrong diet” is the major link for disease manifestation. Hence elimination of this „wrong diet‟ & implementation of corrective diet plays a major role in breaking the „Samprapti‟. The Dietary interventions for Psoriasis or any skin disease can have the following seven components- Nidana Parivarjana, Avashta anusara ahara sevana, Matra consideration, avoiding unwholesome diet, observing proper mental status during food intake, Prescription of specific disease related diet, and very important one- Education about Aahara. The article intends to uplift the importance of holistic approach towards diet prescription rather than only disease specific diet.

The current clinical study was planned to assess the efficiency of Jeemootakaphala Avapeedaka and Pradhamana Nasya in Kosthashakhashrita kamala. The study was completed on 30 patients diagnosed with Kosthashakashrita kamala of either sex, among the age faction of 20 to 60 years who were arbitrarily chosen. The patients were categorized into 2 groups i.e Group A & group B. Jeemootaka phala Avapeedaka Nasya was given to group A, while Jeemootaka phala Pradhamana Nasya was administered in group B. The dosage of Nasya was -1.5 ml in every nostril in group A, 65 mg in every nostril in group B. The evaluation was made before the treatment and after treatment. Patients were followed up after 7 days of Nasya. Hence whole study period was 15 days. Both Nasya showed considerable improvement in Kosthashakhashrita kamala. Clinical efficiency of group A was better than to group B however statistically both groups showed similar efficacy.

Ayurveda being a science learnt, practiced and taught over generations is a discipline codified through centuries in written documents called manuscripts. Manuscripts on medicine ranges between 20,000–1,00,000 in number. A mere 2% of the available material from manuscripts is in printed form. Several treatment priniciples methods and medical formulations are yet to be discovered from the manuscripts for the present day needs. Therefore, a scientific protocol of research methodology for accessing and exploring this knowledge treasure is of immediate necessity. This article provides an alleyway towards the methodology in Medical Manuscriptology to be adopted by a scholar who intends to take up research in Ayurveda manuscripts.

This complete enumeration, cross-sectional comparative study was conducted on 62 (29 females; 46.77% and 33 males; 53.23%) first-year MBBS students of a municipal medical college. After explaining the purpose of the study and orienting students about the OSPE procedure and its marking system, written informed consent was obtained from those willing to participate in the study. In the traditional practical examination (TPE), each student tested near and distant vision, which was followed by viva voce on the same procedure and overall marks (out of 20) were allotted by the examiners. During the OSPE, the examiners were provided with a pre-validated checklist containing 10 steps each for examining near vision and distant vision. These examinations were to be carried out within an allotted time of 5 minutes each. One mark was given for correct performance of each step mentioned in the checklist. The maximum marks obtainable were 20 marks - 10 marks each for testing near vision and distant vision. The difference in the overall mean TPE and OSPE scores was highly significant (Z=11.79; p<0.00001). However, the gender difference in mean scores in both TPE and OSPE was not significant. While testing near vision, 69.35% students ensured adequate lighting in the room while 79.03% students tested visual acuity both with and without glasses for subjects who wear glasses. While testing for distant vision, only 24.19% students enquired whether the subject had been prescribed glasses earlier. Thus, for these three OSPE steps, the difference in scores while testing for near and distant vision was statistically significant. Students obtaining relatively lower scores would require remedial training. A larger study would be necessary in order to generalize the results.

Medicated soaps for external uses are necessary to avoid related infections or diseases caused by some microorganisms. In the present study, four medicated soaps: Dettol, Protex, Dermoviva, and AB+ were investigated for their antimicrobial activities against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella sp and Candida albicans. Marseille soap was used as control. The antimicrobial effectiveness of selected medicated soaps was determined using paper disc and well methods. Soaps tested in the present research work showed varied levels of activity against the tested microbes. Among them, AB+ was the most active product, while Protex showed the lowest activity against the tested organisms’ species.

The present study examined the anticonvulsant activity of the methanol stem bark extract of PK in mice and day old chicks against maximal electroshock (MES), pentylenetetrazole (PTZ), picrotoxin (PIC), and strychnine (STR) induced seizures. The CNS depressant ability of the extract was also investigated using diazepam-induced sleep test, and it was observed to significantly and dose dependently increase the sleep duration in the diazepam sleep test. The extract and fractions significantly and dose dependently increase the latency to onset of seizure in the PTZ and picrotoxin tests. In the strychnine test, the extract significantly increased the latency to seizure onset at the highest dose of 200 mg/kg, though none of the mice was protected from seizure as was the case with PTZ and PIC induced seizures. Considering the overall effect of PK, it may be concluded that the extract contains bioactive principles acting via enhancement of GABA inhibitory activity, and a second possibility via antagonism of the glutamate-NMDA receptors

Citrinin (CIT), a toxin first isolated from Penicillium citrinum, is known for its cytotoxic and nephrotoxic properties. To date, CIT has been identified in various species of Penicillium and several species of Aspergillus Toxic and protective effects of citrinin may be due to its dose relevant. More experimental setup is required to understand the fact clearly.