Background: Numerous secondary metabolites present in plants, such as tannins, terpenoids, alkaloids, flavonoids, and glycosides, have demonstrated antibacterial properties in vitro. Increasing data on the antibacterial properties of medicinal plants are emerging globally. These plants generate secondary metabolites with antibacterial properties, providing an alternative for developing chemical fungicides that are both relatively safe and cost-effective. Coleus aromaticus, a member of the Lamiaceae family, possesses bitter, aromatic, digestive-stimulating, stomachic, anathematic, deodorising, diuretic, and hepatoprotective properties. Aim: The aim of current investigation is to reveal the mechanisms of C.aromaticus leaf bioactive in treating fungal infection. Methodology: Scientific validation of the current investigation was done by computational based molecular docking study of selected lead molecules against 1,3β-Glycan synthase enzyme. Result: The molecular docking results indicating binding energies of -4.02, -6.81,-4.24 and -5.18 kcal/mol for chlorogenic acid, quercetin, rosmarinic acid and rutin respectively. Conclusion: The findings indicated that each selected lead chemical for additional investigation shown significant inhibitory activity against 1,3β-Glycan synthase, hence revealing its anti-fungal potential.

Taking cost-effective and efficient medical and wellness care at a beautiful location while enjoying a great vacation is profound as medical and wellness tourism. The medical and wellness tourism sector can play a decisive role in the growth of the economy, GDP, employment, and foreign exchange earnings of any country in the world. Unani medicine is one of the oldest traditional systems of medicine being practiced in many countries, including India, under the patronage of the Ministry of Ayush, Govt. of India. The principles of treatment employed in the Unani system are four-branched, which include dietotherapy, regimenal therapy, pharmacotherapy and surgery. Of them, the first three modes may be practically applied in the establishment of medical and wellness tourism centres in Unani medicine. Due to its holistic approach, this system of medicine has high potential for the treatment of many chronic ailments, viz., osteoarthritis, liver diseases, vitiligo, obesity, psychosomatic disorders, etc., to name a few, through its unique detoxification therapy called regimenal therapy. Various regimenal procedures, viz., cupping, hirudotherapy, irrigation therapy, etc.; many modified diets, like barley water, honey water, etc.; and certain special pharmacotherapeutics, such as munḍīj va mushil (concoctive & purgative) therapy and muqwaviyyāt (tonics), are useful for the treatment of various illnesses. Incorporation of these detoxification regimens, dietetics, and drug therapy may exert a significant influence on the outcomes of cosmeto-therapeutics, rejuvenation of mind, neuro-rehabilitation, etc. These are some of the core areas where the Unani system may play a stellar role in boosting medical tourism. Hence, the Ministry of Tourism in collaboration with the Ministry of Ayush may devise such ways and means to further strengthen the already existing Unani medical and wellness centres to attract foreign as well as domestic tourists for their healthcare issues.

Gut feeling is what is equivalent to intuition & that is why having a healthy gut is very critical. The gut goes through a myriad of issues like Irritable Bowel Disease (IBD), Irritable Bowel Syndrome (IBS) & Celiac Disease (CD). The high calorie, low fibre or the fast foods contribute to gut issues. The uses of pre-biotic & pro-biotic foods have escalated as the gut related issues have cropped up as the mental issues have catalyzed the gut related issue. The relevance of the article has increased in current circumstances as the new COVID variant of 2025 is attacking the gut. Crohn’s disease is also touched upon in the article while also establishing a link between the gut & the Parkinson’s Disease (PD). As the issue of individualized approach gets a focus among the therapeutics, the article discusses the role of Homoeopathy which is an individualized system of treatment. Further, it delves into other modalities of homoeopathy as a therapeutic approach at mass level.

Introduction: Although, the traditional medicine is frequently used in the treatment of neurological diseases in sub-Saharan Africa particularly in Mali, very few studies have characterized aspects such as the factors influencing the use of traditional medicine, the types of traditional medicine used, the neurological diseases for which traditional medicine is used, and the adverse events linked to traditional medicine. The aim of our work was to enrich the Neurology Department's data on neurological diseases and traditional medicine, focusing on the different types of traditional medicine used, the factors influencing their use, the neurological diseases for which traditional medicine is used and the adverse events related to traditional medicine use. Method: This was a prospective, cross-sectional study of outpatients and inpatients seen in the neurology department at CHU Gabriel TOURE, conducted over three (3) months. The data collected were entered and analyzed using the following software packages: SPSS version 22.0, Microsoft office Excel 2010 and Epi InfoTM 7. We performed a univariate analysis to obtain the mean and standard deviation for quantitative data, and the numbers and percentages for qualitative data. In the bivariate analysis, Chi-square and Fisher's exact tests were used to determine a significant association between the categorical independent variables and the dependent variable. Values of p<0.05 are considered statistically significant. Results: Of the 106 patients admitted for consultation or hospitalization during the study period, the majority (91.5%) used traditional medicine. Patients with neurological diseases who used traditional medicine accounted for 57.5%. Stroke was the most frequent neurological diseases that motivated our patients to consult or to be hospitalized in the Department of Neurology (36.8%), followed by lumbo-radiculopathy (17.9%). Belief in traditional medicine was the most prevalent factor influencing the use of traditional medicine (57.4%). The majority of patients (83.6%) attributed their illness to divine punishment. Phytotherapy was the most common type of traditional medicine received by our patients (55.7%), followed by massage (27.9%). The majority of our patients had no adverse events (95.3%). Patients with epilepsy and low back pain were more likely to use traditional medicine than those who did not use traditional medicine (RR= 4.80; 95% CI= (1.14 - 20.20) and p= 0.006; RR= 6.27; 95% CI= (1.53 -25.78); p= 0.000). The use of phytotherapy was significantly more frequent in patients seen for stroke (p=0.000) and epilepsy (p=0.002) than others types of traditional medicine. In addition, massage was most frequently used in patients with low back pain (p=0.000) others types of traditional medicine. Conclusion: Our study showed that the majority of our patients used traditional medicine. More than half of patients with neurological diseases used traditional medicine. Factors influencing the use of traditional medicine were mainly dominated by belief in traditional medicine and cultural attachment to traditional medicine. The most commonly used types of traditional medicine are phytotherapy and massage. Neurological diseases for which traditional medicine is used are dominated by stroke and lomboradiculopathy. Almost all our patients have not experienced any adverse effects from traditional medicine.

Ali ibn Isa Al-Kahhal, a medieval Muslim ophthalmologist, remains an underappreciated yet pivotal figure in medical history. His seminal treatise, Tadhkirat al-Kahhalin (The Notebook of the Oculists), is one of the earliest and most comprehensive works on ophthalmology, detailing ocular anatomy, pathology, and surgical techniques. This paper critically examines existing literature on Ali ibn Isa, analyzing his contributions, methodological approaches, and the factors contributing to his relative obscurity in modern historiography. The review highlights his systematic classification of over 130 eye diseases, including pioneering descriptions of cataracts, trachoma, and optic nerve disorders. His surgical innovations, such as the couching technique for cataract removal, were groundbreaking for their time and laid the foundation for future advancements. Moreover, his emphasis on empirical observation and case-based diagnosis anticipated modern clinical methodologies. Despite these achievements, Ali ibn Isa’s legacy has been largely overshadowed by figures like Ibn Sina and Al-Razi. His limited recognition stems from Eurocentric biases in medical history, the fragmentation of Arabic medical manuscripts, and the specialized nature of his work, which may have constrained its broader impact. By re-evaluating his contributions, this study underscores the necessity of integrating non-Western medical traditions into global medical historiography. This paper argues that Ali ibn Isa’s work deserves greater scholarly attention for its historical significance and role in transmitting medical knowledge across cultures and periods. A more inclusive reassessment of medical history offers a richer understanding of the diverse intellectual traditions that have shaped contemporary medical practice.

This thesis aims to explore the intricate interactions, reactions, and counteractions of vitamins within the human body. Vitamins are essential organic compounds required in small quantities for the proper functioning of various physiological processes. While each vitamin plays a unique role, their interdependencies and potential for interactions are crucial to understand. This thesis examines the mechanisms behind vitamin interactions, including absorption, metabolism, and potential antagonistic or synergistic effects. By delving into these complexities, this research seeks to contribute to a comprehensive understanding of how vitamins interact, react, and counteract with each other, and their implications for human health