Now a days the significance of Yoga & Naturopathy are being realized by human being for health. The true and right meaning of Yoga & Naturopathy is conceived by intellectuals and common people may be different. People of the modern era are pre-occupied with the meaning and essence of Yoga & Naturopathy. It could be renouncing the worldly matter and lead an acetic life and limiting our desires. Some view it is as nothing but some physical exercise and postures and some take it as breathing techniques which leads to sound mind & body. All these meanings are superficial and can be considered as an fair attempt to know only the profit of Yoga & Naturopathy in this materialistic world, where everything is looked upon as source of profit or loss. But the true meaning of Yoga & Naturopathy are beyond that both are about understanding the human health and it’s potential. Yoga & Naturopathy both are important factors of human health which brings consciousness among ourselves to realize our true nature a science of right living and significant force in the development of personal health. By the principles of Yoga & Naturopathy in to or varied lifestyle, we can systematically balance the physical, mental and emotional dimensions of our health. Yoga & Naturopathy are the natural way to cure and maintain our health.
ORIGINAL RESEARCH ARTICLE | May 16, 2025
Qualitative Determination of Sildenafil and Tadalafil Adulterants in Selected Herbal Aphrodisiac Products
Adesegun J. Kashimawo, Miller E. Emmanuel, Samuel J. Bunu
Page no 64-71 |
https://doi.org10.36348/sijtcm.2025.v08i05.002
The increasing global demand for herbal aphrodisiac products has raised concerns regarding their safety and quality due to potential adulteration with synthetic or conventional pharmaceutical active ingredients. This study investigates the presence of sildenafil and tadalafil in selected herbal mixtures marketed for sexual enhancement available in Nigeria, including Mai Sulhu, Mai Rahusa, Mai Sasangi, Jaolin, Saigari Jawaye, and Manisa. A combination of preliminary phytochemical screening, Thin-Layer Chromatography (TLC), and Fourier Transform Infrared Spectroscopy (FTIR) analysis was used to analyze the samples. Phytochemical screening using Dragendorff’s reagent indicated the presence of alkaloids in five of the samples, except Jaolin, suggesting the inclusion of bioactive compounds. TLC analysis revealed that four herbal mixtures had Retention Factor (Rf) values matching those of tadalafil, 0.60 (Mai Salhu and Mai Rahusa), and sildenafil citrate, 0.47 (Saigari yawaye and Manisa), indicating possible adulteration. FTIR spectroscopy further confirmed the presence of these synthetic phosphodiesterase-5 (PDE-5) inhibitors, as spectral peaks in some samples closely correlate with those of sildenafil and tadalafil. The detection of these undeclared pharmaceuticals poses significant health risks, including cardiovascular complications and hazardous drug interactions, as well as potential erectile dysfunction. These findings emphasize the need for stricter regulatory oversight, improved quality control measures, and public awareness regarding the risks associated with adulterated herbal aphrodisiacs. Routine screening using advanced analytical techniques such as High-Performance Liquid Chromatography and Mass Spectrometry is recommended to enhance detection accuracy and precision.
ORIGINAL RESEARCH ARTICLE | May 22, 2025
Analysis of Prescribing Pattern of Drugs in Chronic Obstructive Pulmonary Disease Patients at a Tertiary Care Teaching Hospital
Akshaya A, Biyunisha, Ramprasad M, Shahana K A, V. Karthikeyan, C.I. Sajeeth, Jesin Kumar
Page no 72-79 |
https://doi.org10.36348/sijtcm.2025.v08i05.003
Chronic Obstructive Pulmonary Disease (COPD) is a common, progressive lung condition which significantly impacts the quality of life. Despite the existence of clinical guidelines, irrational prescribing patterns, remain common. Analysing prescription patterns and evaluating drug use can identify issues with prescribing patterns and provide valuable guidance to medical professionals. This study thus aims to analyse the prescribing practices of patients with COPD in order to determine areas for improvement, rationality, and adherence to guidelines. A prospective observational study was conducted among 113 COPD patients. Data on demographics, clinical status, and treatment (drug type, dosage, frequency, duration, and route of administration) were collected. WHO core prescribing indicators were applied along with analysis of drug classes, fixed drug combinations, and rescue medications. Majority of patients were between the ages of 61 and 75. 46.8% of individuals had a history of smoking, and 67.2% of cases had comorbidities. Of the 608 medications provided, 43% dealt with comorbidities and 57% targeted COPD. The most commonly utilized medications were bronchodilators (38.8%), corticosteroids (16.45%), and antibiotics (18.75%). In 72.5% of cases, beta-2 agonists were prescribed. ICS and combination mucolytics were preferred. The prescribing pattern reflected rational COPD management. According to this study, the most commonly prescribed drug classes for the treatment of COPD are bronchodilators, corticosteroids, and antibiotics. There is a visible overuse of antibiotics and brand-name prescriptions, which deviates from WHO core prescribing indicators. Ongoing prescription audits and educational interventions can thus promote rational drug usage and improve patient outcomes in the treatment of COPD.
ORIGINAL RESEARCH ARTICLE | May 24, 2025
Prescribing Patterns in Moderate to Severe Chronic Kidney Disease Patients with Associated Comorbidities
Gincy Varghese, Indraja K C, Jisni Jayaraj, Vaishnavi V Gopal, Dr. Vini Pavithran, Dr. Leena Jose
Page no 80-86 |
https://doi.org10.36348/sijtcm.2025.v08i05.004
Introduction: A comprehensive systematic review and meta-analysis reported that chronic kidney disease (CKD) has a worldwide prevalence of around 13.4%, underscoring its emergence as a global health concern [1,2]. Alongside CKD, patients are often affected by multiple co-morbidities such as hypertension, diabetes, and cardiovascular disorders [2-4] Methodology: A prospective observational study was conducted over six months in the Department of Nephrology at Karuna Medical College Hospital, Chittur, Palakkad. The study enrolled adult participants aged 18 to 70 years with moderate to severe chronic kidney disease (CKD). Patients were classified into CKD stages G1, G2, G3a, G3b, G4, and G5[5] Results: Table 1 shows the association of CKD stages across various demographic factors, BMI, and comorbidities. There was no statistically significant association between age and CKD stages. Among 188 patients maximum cases were observed in CKD stage V (34.57%), followed by CKD stage IV (27.65%). Table 3 shows that a higher number of patients were prescribed cilnidipine (27.4%), followed by telmisartan (19.0%), and the lowest number of patients were prescribed metolazone (1%), vasopressin (1%), and verapamil (1%). Table 4 shows that a higher number of patients were prescribed insulin (32.25%), followed by linagliptin (28.0%), and the lowest number of patients were prescribed voglibose (0.53%). Conclusion: This study emphasized the complexities involved in treating patients with chronic kidney disease (CKD), particularly when co-existing health conditions are present. It provided valuable information on current clinical practices and foundational data relevant to managing such patients.
ORIGINAL RESEARCH ARTICLE | May 27, 2025
Understanding Niqris (Gout) in Unani Medicine: Classical Perspectives on Etiopathogenesis
Ahmad Zeeshan, Mohammad Shamsul Huda, Irfan Ahmad, Arshad Kafi
Page no 87-93 |
https://doi.org10.36348/sijtcm.2025.v08i05.005
Gout is a metabolic condition characterized by recurrent episodes of acute arthritis, primarily resulting from the deposition of monosodium urate crystals in and around the joints. Recognized as one of the oldest known diseases, it is referred to as Niqris in the Unani system of medicine. This system is based on the Hippocratic concept of the four humours (Akhlāṭ): Dam (blood), Balgham (phlegm), Ṣafrā’ (yellow bile), and Sawdā’(black bile). According to Unani medicine, such disorders arise from an imbalance of these humours, alteration in Mizāj’(temperament), and the accumulation of abnormal substances (Mawad-e-Fasida) in the joint spaces. Classical Unani physicians believed that Niqris typically affects individuals who have an excessive buildup of abnormal humours and are unable to eliminate them from the body. These retained substances settle in the joints, set off inflammatory responses marked by sharp pain, swelling, redness, and heat. This study aims to analyze the Unani perspective on the etiopathogenesis and clinical features of gout, as documented in classical texts, research articles, and manuscripts. The findings highlight the depth of Unani medical understanding and its potential role in guiding effective preventive and therapeutic strategies for the management of gout.