Background: Male infertility is a significant reproductive health concern affecting millions of couples worldwide. While conventional medical interventions offer viable solutions, an increasing number of individuals are turning towards traditional medicine, specifically herbal products, as an alternative approach to managing male infertility. Methods: The study employed a mixed-methods approach, combining quantitative and qualitative data collection methods. A survey questionnaire was administered to 100 consented adult men with fertility issues to explore their beliefs about traditional medicine and the effectiveness of the herbal products they used. Results: Out of the 100 participants recruited, about 74% preferred herbal products over orthodox medicines to manage infertility. The majority (75%) thought that herbal products were effective in managing male infertility, 41% of them noticed a change in their sperm parameters after using the herbal product of interest, and (33%) thought that the herbal product was responsible for them impregnating their partners. Most respondents (93%) did not experience any side effects after using the herbal products, with only a few of them (7%) reporting side effects. Conclusions: People's beliefs about traditional medicine vary based on their personal experiences and those of others. Based on research findings, herbal products' effectiveness in managing male infertility has shown promising results and should be investigated further.

Background: Many secondary metabolites found in plants, including tannins, terpenoids, alkaloids, flavonoids, glycosides, etc., have been shown to exhibit antibacterial activities in vitro. Man has long been aware of herbal treatments. Traditional medical practitioners have detailed the therapeutic usefulness of numerous indigenous herbs for a variety of illnesses. More and more reports of medicinal plants' antimicrobial qualities are coming in from all over the world. By producing secondary metabolites with antibacterial characteristics, these plants offer another option for creating chemical fungicides that are both reasonably safe and reasonably priced. The Lamiaceae family member Coleus aromaticus is bitter, aromatic, digestively stimulating, stomachic, anathematic, deodorant, diuretic, and liver-tonic. Aim: The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some fungal strains. In the present study, the microbial activity of hydroalcoholic and methanolic extracts of leaves of Coleus aromaticus Linn. (an ethnomedicinal plant) was evaluated for potential antimicrobial activity against medically important fungal strains. Method: The antimicrobial activity was determined in the extracts using agar disc diffusion method. Result: The zone of inhibition for different strains of fungia i.e. CA, CA, AN were determined. The outcome of the investigation revealed that hydroalcoholic leaf extract of CA is more effective than methanolic extract as compare to standard due to presence of flavonoids. Conclusion: Both extracts (MeoH & HAE) showed effective antifungal activity, of which the HAE demonstrated the potent antifungal activity due to high flavonoid content.

Background: Cardiovascular diseases (CVDs) represent the most prevalent non-communicable diseases worldwide. In 2019, around 17.9 million individuals succumbed to cardiovascular diseases, accounting for 32% of all global fatalities. Mitochondria are essential for maintaining cellular metabolic equilibrium, facilitating cell survival and apoptosis, and generating the majority of cellular energy. Protein–protein interactions (PPIs) play a crucial role in both physiological and pathological processes, with abnormal PPIs linked to numerous disorders, making them prospective pharmacological targets across diverse therapeutic domains. Peptides are highly promising as protein-protein interaction inhibitors due to their capacity to replicate natural interaction patterns and encompass rather extensive interaction regions. Computational methods are extensively employed to accelerate drug discovery by screening prospective lead molecules. Purpose: Current work was designed to check efficacy of Daucus carota flavonoid for cardioprotective activity. Methodology: Scientific validation of the current investigation was done by computational based molecular docking study of lead molecules of Daucus carota pulp against malonyl Co-A decarboxylase enzyme. Result: The flavonoid found in D.carota has been identified as an effective cardioprotective drug and their lead molecules luteolin and apigenin demonstrating effective binding to the target protein malonyl Co-A decarboxylase with binding energies of -7.34 and -7.12 kcal/mol, respectively. Conclusion: The findings indicated that each selected lead chemical for additional investigation shown significant inhibitory activity against malonyl Co-A decarboxylase, hence revealing its cardio protection potential.