Panchakarma is unique and super specialized therapy in the Ayurveda. It is very particular and result oriented natural therapy of body purification. Panchakarma includes five natural methods of Purification or elimination viz, Vaman, Virechan, Basti, Nasya and Raktamokshana. Panchakarma therapy has promotive, preventive and curative approach towards curing various disorders in Shalakya Tantra. Shalakya Tantra is one of the important aspects of the Ayurveda which deals with the treatment of disease associated with body parts above the neck i.e.,Netra (eye), Karna (ear), Nasika (nose), Kantha (throat), Aushtha (lips), Danta (teeth), Dantamoola (root of teeth), Jihwa (tongue), Taalu (palate), Kantha (throat), Sarvasar (mouth) and Shira or Kapala (head). Four out of five sense organs are included in Shalakya Tantra, so it is very important to protect them from diseases and also maintain their proper functioning. Administration of drugs by the Nasal route is termed as Nasya. Panchakarma is the most essential part of Ayurveda treatments. For administration of medicine, different routes are used in Ayurveda, but to reach the “Shira” (Head) it is difficult with other routes, there by the “Nasya” Karma was developed. Nasya Procedure is to eliminate vitiated Kapha Dosha associated Pitta disorders or diseases originating or settled in the place of Kapha.

The main aim and objective of Ayurved is “Swasthyasya Swasthya Rakshnam” “Aaturasya Vikara Prasamanam” Which means maintaining the health of a healthy person, prevention of disease and curing the disease of ailing person. The Shalakyatantra, a part of Astanga Ayurved, deals with the disease above throat. It includes the disease and treatment of Netra, Karna, Nasa, Kantha, Mukha, Danta and Siro-Kapala Gata Roga. Sansamana (conservative), Samsodhana (Panchakarma) and the Shastra chikitsa (surgical procedures) are the essential treatment modalities followed to treat a disease. Panchakarma is a branch of Ayurveda, meant for the removal of vitiated Dosha, Mala or toxic part of body and balances Dosha-Dushya through, Vamana, Virechana, Nashya, Basti, Rakta Mokshana etc. In the disease like Abhisyanda, Adhimantha, Timira, Danta Nadi, Upakusha and Dusthapratishyaya, most of the Panchakarma therapies are indicated according to their severity of the disease. In practice the patient, who undergoes Panchakarma or Sodhana Chikitsa shows better result than the patient treated without Sodhanakarma. it is the process, which gets the root cause of the problem, and correct the essential balance of Tridosha in the body. Therefore, increasing and mainstreaming the Panchakarma procedure in Shalakya Tantra will definitely provide an effective and satisfactory outcome in Urdhwajatrugata disorders. Now a days ENT & Ophthalmic diseases are major concerned because patient could not want to go for surgical procedure. Looking towards Ayurved, there are lot of Panchakarma Procedures are advocated for this disorders.

Background: Bordetella pertussis is the causative organism of an acute human respiratory tract disease known as pertussis – an endemic disease globally with reported cases in both developing and developed countries. This study evaluated the anti-bacterial potentials of the crab specie (Goniopsis pelli) extract on bordetela pertussis in Swiss mice. Methods: One hundred and twenty-two (122) animals (Swiss mice) were divided into five groups for the curative treatment study. Groups 1 and 2 were the normal and negative controls respectively, while groups 3 and 5 received (300mg/kg and 600mg/kg) of the extract and group 5 received 4000mg/70kg of erythromycin. Blood and kidney samples were collected on 0, 6th, 12th and 18thday for lipid profile analysis and kidney histological examination. Result: The result shows that Animals exposed to B. pertussis inoculum dose (5.0x105cfu/ml) without treatment caused a decrease in the plasma level of high density lipoprotein cholesterol (HDL) and an increase in the concentration of total cholesterol, triglycerides and low density lipoprotein cholesterol (LDL). However, treatment with Goniopsis pelli extracts reversed the observed effect thereby producing a gradual increase in HDL levels and decrease in triglycerides, cholesterol and LDL levels with no adverse effect on the kidney histology. Conclusion: Goniopsis pelli has the potentials of ameliorating lipid abnormalities and plays a therapeutic role in improving lipid profiles associated with the bacterial infection.