ORIGINAL RESEARCH ARTICLE | May 5, 2023
The Prevalence of Anaemia in Infants and Children Aged 2-59 Months Hospitalised in the Paediatric Ward of the CSREF CII in the District of Bamako
Chaka Keita, Kadiatou BA, Ouazoun Coulibaly, Salif Djiguiba, Sidi Toure, Fatoumata Sylla, Salia Ouonogo, Hachimi Poma, Samou Diarra, Hawa Coulibaly, Kassoum Ouattara, Boubacar Niare, Bakary Abou Traore, Abdramane Traore, Oumar Diallo, Harouna Ouatara
Page no 53-57 |
10.36348/sijtcm.2023.v06i04.001
Introduction: Anemia remains a public health problem in both industrialized and developing countries. Developing countries have the highest prevalence, especially in children. The objective of this study was to determine the prevalence of anaemia in children aged 2-59 months in the paediatric ward of the commune II health centre in Bamako. Methods: This was a retrospective, descriptive study which took place from 1 January 2017 to 31 December 2018, i.e. a period of 2 years. All children aged 2 months to 59 months hospitalised with clinical anaemia who had a blood count or haemoglobin and/or haematocrit measurement hospitalised in the paediatric ward during the study period were included. Anemia was defined according to WHO criteria. The etiological search was guided by clinical signs and complementary examinations. Results: The prevalence of anaemia was 16.63%. The age group 12 to 23 months was the most represented. The children were predominantly male (56%). The anaemia was severe in 50%, moderate and mild in 50%. The anaemia was predominantly microcytic and hypochromic in 68%. Fever was the first reason for consultation in 75% and malaria was the main pathology in 56%. The mortality rate of anaemic patients was 3%. Conclusion: Anemia is a real problem among children in commune II. The main etiology was malaria. Strengthening malaria prevention could reduce its incidence.
ORIGINAL RESEARCH ARTICLE | May 6, 2023
Phytochemical Screening of Ginger (Zingiber officinale), a Medicinal Plant
Hetavi J. Thakor , Yesha S. Rathi , Dr. Nisha S. Nayak
Page no 58-62 |
10.36348/sijtcm.2023.v06i04.002
Ginger has potent values as a medicinal plant which originated from China and India. Currently there is a renewed interest in ginger because of its various active pharmacological ingredients including gingerols, beta-carotene, capsaicin, caffeic acid, curcumin, and salicylate making it a potential source of research to use as a drug. The present study was aimed at extraction of ginger root extract in acetone and methanol solvents by Soxhlet extraction method, screening of phytochemical constituents of ginger extract in acetone and methanol and evaluation of its antimicrobial activity against known pathogenic microorganism. The qualitative analysis of phytochemicals revealed the presence of saponins, alkaloids, flavonoids, and steroids in the extracts of ginger. Results of antimicrobial activity showed that ginger in acetone was having highest activity against Escherichia coli MTCC 334 with 24 mm of clear zone and lowest activity with ginger in methanol against Bacillus subtilis MTCC 441 with 10 mm of clear zone.
ORIGINAL RESEARCH ARTICLE | May 7, 2023
Phytochemical screening of the Herbal Formulation of Morinda citrifolia and Costus afer Leaf Extracts
Nnaoma Ikenna Elvis, Joseph Rich, Ojimelukwe Chizoba, Nwabueze Robinson
Page no 63-66 |
10.36348/sijtcm.2023.v06i04.003
Medicinal plants not only supplement or replace the frequently insufficiently available modern medical treatments but also improve the local population's health and security. As a result, these plants are essential to daily life and have strong ties to a wide range of social, cultural, and economic events related to birth, growth, aging, illness, and death. The formulation of Morinda citrifolia and Costus afer undergoing phytochemical screening in methanol extract. The phytoconstituents discovered in the formulation were tannin, terpenoid, flavonoid, alkaloid, cardiac glycoside, glycoside, saponins, etc. The therapeutic value of a medicinal plant is determined by its phytoconstituents, either singly or in combination. Some of the significant phytochemicals with various biological activities include alkaloids, flavonoids, phenolics, tannins, saponins, steroids, glycosides, terpenes, etc. The identification of the phytochemicals can be used to predict the pharmacological activity of a plant. The formulation used in literary works contains phytoconstituents that have been linked to a variety of pharmacological actions. Therefore, these plants may be exploited to create medications that are efficient against diabetes, heart attack, bacteria, and microorganisms as well as cancer cells.
REVIEW ARTICLE | May 24, 2023
The Concise Overview of Unani Treatise Contemplating Oral Health and its Associated Common Conditions
Ayesha Parveen, Atiya Anjum, Ammar Ibn Anwar, Sadaf Firdaus
Page no 67-70 |
10.36348/sijtcm.2023.v06i04.004
Oral health is essential to quality of life because it promotes social and physical well-being and serves as a reflection of general health. According to some estimates, dental and oro-dental conditions are the most prevalent illnesses in the world. One important known predisposing factor for various oral illnesses is poor oral hygiene. Since the beginning of recorded history, mankind has suffered from oral diseases in all of its manifestations. Ancient Chinese, Greek, Roman, Egyptian, Arabic, and Indian surgical and medical treatises all discuss mouth illnesses at some point. Many renowned Unani physicians have too mentioned about various oral diseases and unhygienic conditions in their respective books. They have clearly mentioned how to maintain oral health and treat various oral conditions in their respective rich Unani texts. Present review paper is an attempt to throw some light over oral hygiene, its historical background and diseases which occur due to poor oral health light of the Unani literature.
ORIGINAL RESEARCH ARTICLE | May 27, 2023
Tumor Lysis Syndrome in Adults with Hematologic Malignancies
El Fegigi Mohamed, Khalki Hanane, Bentahar Rihab, Regragui Safae
Page no 71-74 |
10.36348/sijtcm.2023.v06i04.005
Introduction: Tumor lysis syndrome (TLS) is a metabolic complication commonly seen in patients with hematologic malignancies, particularly high-grade non-Hodgkin lymphomas and acute leukemia. It is characterized by biochemical abnormalities that can lead to cardiac, neurological, and renal complications that can be fatal. The purpose of our study is to describe the epidemiology, laboratory profile and the outcome of TLS in order to identify patients at risk, and to implement appropriate prophylactic measures to prevent the clinical repercussions. Material and Methods: This work is a retrospective study of all patients who developed a laboratory TLS in hematologic malignancies according to the classification of Cairo and Bishop over a period of 3 years (from November 2019 to November 2022), and whose data were collected at the adult hematology unit of the Mohammed VI University Hospital of Tangiers. Results: The incidence of TLS among hematologic malignancies identified during this period was 3.7%. The underlying disease was acute leukemia in 10 patients (55.6%) and high-grade lymphoma in eight patients (44.4%). TLS was spontaneous in fifteen cases (83%) and chemotherapy-induced in three cases (17%). All our patients presented with hyperphosphatemia. 94% of cases had hyperuricemia, 44% of cases had hypocalcemia, while 6% of cases had hyperkalemia. Lactate dehydrogenase levels were elevated in all cases. Treatment consisted of hyperhydration and administration of hypouricemic agents in all cases. Three patients received hemodialysis. The outcome was favorable in 83% of cases and 17% of cases died during follow-up. Conclusion: TLS is a severe complication, most often seen in highly proliferative hematologic malignancies. The role of the laboratory remains paramount in the diagnosis of TLS and in the biological monitoring after the implementation of appropriate therapeutic measures.