REVIEW ARTICLE | March 8, 2022
Therapeutic Potential of Azadirachta indica (Neem)-A Comprehensive Review
Hafiza Anam Asghar, Syed Qamar Abbas, Muhammad Kamran Arshad, Asra Jabin, Bakhtawar Usman, Mueez Aslam, Azeem Asghar
Page no 47-64
Background: Plant based traditional health care is one of the ancient remedies used to prevent and treat many health-related disorders. Due to increasing cost of medicine in the modern era, people are now moving towards the utilization of ancient ethno medicinal plants-based remedies to prevent and treat diseases as well as to maintain their health. Azadirachta indica, commonly known as neem has been used since ancient times as ethno medicinal plant due to its pharmacological and therapeutic potential. Different parts of this plant including leaves, fruit, bark, seeds and flowers can be used to prevent many diseases. Many structurally complex and biologically active components can be extracted and utilized from different parts of neem. Purpose: Purpose of this review is to highlight the importance of different parts of neem as they contain various biologically active components that are beneficial in prevention and treatment of various health related disorders. Method: Science direct, Google scholar, Web of Science and PubMed were accessed to review the therapeutic potential of neem in different diseases. Results: Neem has been demonstrated to exhibit anti-cancer, immunostimulant, orodental, skin protection, neuropharmacological, ulcer treating, anti-pyretic, anti-inflammatory, anti-malarial, anti-bacterial, anti-fungal, anti-viral, anti-parasitic, anti-hyperglycemic, antioxidant, anti-hyperlipidemic, hepatoprotective, renal protection and hematological parameters maintaince properties. Conclusion: There is no evidence of adverse effects of neem in literature. Only the people who are allergic to it can have side effects otherwise it is stomach friendly in all conditions due to which it can be used for treatment of various health related disorders.
REVIEW ARTICLE | March 16, 2022
A Review on Antimicrobial Activity of Tarunyapidikahara Lepa Ingredients
Usha Sharma, Shiwali Sharma, Punam Kumari, Shuchi Mitra, Yadevendra Yadav, Khem Chand Sharma
Page no 65-71
Skin is not only a protecting covering of our whole body but also it reflects the physical and mental health. Mukhdushika is the most common skin ailment in the teenage of youngsters, it disfigure the face. Acne vulgaris is chronic inflammatory condition of the pilosebacous follicles and caused by the Propionibacteriun acnes. It is correlated with Mukhdushika, a disease mention in Ayurveda. Microbial infections are the leading cause of diseases and disease related mortality. Non–judicious intake of antibiotic is the serious concern for antibiotic resistant strain of bacteria. Antimicrobial resistance (AMR) threatens the ability to successfully treat infectious diseases across the world. Among the most common skin pathogens Pseudomonas aeruginosa (gram-negative pathogen) has high antibiotic resistance rate and Staphylococcus aureus is another most common human pathogens that leads to many types of local infections such as wound, post-operative infection and also for prosthetic infections. S. aureus is also known for its ability to resist antibiotics such as penicillin, methicillin, tetracycline, erythromycin and vancomycin, so there is a need of different treatment to overcome the problem of AMR. Similar problem is also arises in the treatment of acne by antibiotics. Tarunyapidikahara Lepa is an Ayurvedic formulation consisting of equal amount of Lodhra (Symplocos racemosa Roxb), Dhanakya (Coriandrum sativum Linn.) and Vacha (Acorus calamus Linn) prescribed for topical application in Mukhdusika in renowned text Chakradatta, Kshudra Roga Chikitsa. This appraisal summarizes the antimicrobial potential of each ingredient present in the Tarunyapidikhara Lepa.
ORIGINAL RESEARCH ARTICLE | March 25, 2022
Practical Knowledge and Attitudes of Pregnant Women on HIV/AIDS at the Nianankoro FOMBA Hospital in Segou
Traoré. T, Traoré S, Dao SZ, Camara. A, Donigolo. B, Sidibé. K, Traoré. B, Sanogo. A, Bagayoko TB, Koreich. M, Traore Bah A, Coulibaly A, Diarisso. A, Bocoum. A, Fané. S, Kané F, Traoré .Y, Teguété. I, Théra A, Dolo. A
Page no 72-76
Introduction: According to epidemiological surveillance in Mali in 2013, the prevalence of HIV/AIDS infection is high among pregnant women in the Ségou region. Objective: The aim of our study was to study the knowledge and practical attitudes regarding HIV/AIDS of pregnant women followed in prenatal consultation in the gynecology-obstetrics department of the Nianankoro Fomba hospital in Ségou. Method and material: This was a prospective descriptive cross-sectional study that took place from September 1, 2019 to April 31, 2020. Included in the study were all consenting pregnant women seen in prenatal consultation (CPN) or in labor at the hospital. Results: The seroprevalence of HIV/AIDS in our study was 1.4%. The age group of 20 to 29 years was the most represented in our study with 51.1% of cases with an average of 26.5 years. The pregnant women were housewives in 96.1% of cases. The main source of information for pregnant women on HIV/AIDS was television (44.2%). The best-known mode of transmission was sexual (47.7%) and weight loss was considered the main sign of HIV by 27.5% of the pregnant women questioned. The VH screening rate was inversely proportional to the level of education P=0.062. About 82.3% of pregnant women favored psycho-emotional support for people living with HIV (PV-HIV). The acceptance rate of pregnant women for HIV/AIDS screening was 87.8%. The fear of being stigmatized (46.0%) was the frequent reason for refusing the screening test. Fidelity was cited as the main means of preventing HIV transmission by 35.7% of pregnant women. Conclusion: Our study reveals that the level of knowledge of pregnant women on the modes of transmission and measures to prevent mother-to-child transmission of HIV/AIDS is generally good. However, awareness should always continue to bring the reluctant to take the screening test.
REVIEW ARTICLE | March 30, 2022
Etiopathgenesis of Dadru in Ayurveda: A Review
Sharma Arun, Yadav Yadevendra, Mitra Shuchi, Sharma Khem Chand
Page no 77-81
In recent years, Twak Vikar (Dermatological manifestations) are common and more so frequent in the elder age. There is a definite increase in its incidence especially, in the tropical region and developing countries like India due to various reasons like unhygienic environmental conditions, poverty, poor sanitation, illiteracy, malnutrition, improper skin care etc. The patients of skin disease are additionally prone to experience physical, emotional & socio-economic embarrassment in the society due to disfigured appearance. Dadru is one of the commonly occurring skin diseases which can be defined as an entity manifested by intractable itching, scaling, erythema with the lesions discoid in shape. Dadru, is a Kapha (Energy that forms the body’s structure) Pitta (Body’s metabolic system) Pradhan (prominent) Vyadhi (Disease). Acharya Charak has placed Dadru under Kshudra Kushth (Minor skin disease) but Acharya Sushrut and Acharya Vagbhata kept it under Mahakushth (Major skin disease). Acharyas did not explained separate Nidan (causative and diagnostic factor) for Dadru Kushth. The knowledge of Nidan is helpful for proper Diagnosis, prevention and treatment of disease.