Background: Hysterectomy is a major and common gynecological procedure that involves the removal of the uterus for benign or malignant indications. The rate of hysterectomy varies from one region to another. Objective: To determine the prevalence, indications and clinical outcome of hysterectomy at Rasheed Shekoni Federal University Teaching Hospital. Materials and methods: The study was a 3-year retrospective review of hysterectomies, carried out between 1st July 2020 and 31st June 2023. Data analysis was carried out using IBM SPSS version 26. Measured variables were expressed in percentage. Test for association was done using chi-square, setting P-value at <0.05. Results: A total of 56 hysterectomies were performed out of a total of 232 gynecological surgeries, giving a rate of 24.14%. The mean age was 51.72±12.2 years. The mean parity was 5.28±3.3. The rate of hysterectomy was highest (34.0%) among women aged 40 – 49 years. The commonest (29.8%) procedure was vaginal hysterectomy. The commonest (29.8%) indication for hysterectomy was utero-vaginal prolapse. The mean blood unit transfused was 1.2±1.2 units. The mean post-operative admission was 5.23± 2.2 days. Conclusion: Pelvic organ prolapse is the leading indication for hysterectomy and vaginal hysterectomy is the most common type of hysterectomy performed.

We report in this article the case of a patient treated for nipple Paget's disease and in whom clinical and radiological investigations found the association of Paget with carcinoma in situ and infiltrating carcinoma of the breast. Paget's disease of the nipple is a rare variant of CIS. It is associated with an underlying breast adenocarcinoma in more than 80% of cases. Its research must be systematic in imaging, namely MRI. The management of Paget's disease depends on whether or not it is associated with carcinoma in situ or invasive carcinoma. Through our case and in the light of the review of the literature, we insist on the particularity of the positive and differential diagnosis of this entity as well as the therapeutic side, the good knowledge of which allows practitioners to make the diagnosis in time and therefore to improve the prognosis of these young patients.

Introduction: High-risk & severe-risk pregnancies are characterized by increased risks of complications for both the mother and the fetus, which can result from several factors such as maternal age, medical situations, lifestyle habits, and previous pregnancies. These complications are a major concern, mostly in developing countries like Bangladesh, where maternal and infant mortality rates remain high. Maternal complications associated with high-risk and severe-risk pregnancies may include maternal death, severe bleeding, sepsis, and hypertensive disorders, while fetal complications may include preterm delivery, fetal growth restriction, and stillbirth. The objective of this study was to investigate the perinatal outcomes of high-risk and severe-risk pregnancies. Methods: This prospective purposive study was carried out on the admitted patients in the Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from July 2007 to December 2007. Total hundreds of risk groups pregnant women (N=100) were enrolled in the study among them eighty-five (n=85) scoring 3-6 included as high risk pregnancy and fifteen (n=15) scoring 7 or more included as severe-risk pregnancy. All relevant data were recorded for each individual study subject on predesigned data collection sheet. All collected data were compiled and analyzed by computer-based statistical software (Instat). Chi-square tests were performed to compare the prevalence of study variables where, p < 0.05 considered the level of significance with 95%CI. Ethical clearance of this study was obtained from the Institutional Review Board (IRB) of BSMMU, Dhaka, Bangladesh. Results: In the high-risk group (n=85), around one-fourth of the patients (22,25.9%) and in a severe- risk group (n=15), one patient (1,6.7%) underwent vaginal delivery, Caesarean section was done in sixty-three patients (63,74.1%) in high-risk pregnant women and fourteen patients (14,93.3%) in severe-risk pregnant women respectively. The distribution of risk group and mode of delivery is statistically highly significant (P <0.001). Out of sixty-three patients (n1=63), nineteen (19, 30.2%) were required to be delivered by caesarean section for fetal distress and fifteen (15, 30.16%) were malpresentation. Out of forty-one patients (n2=14), the most common indications were a history of previous caesarean section with multiple risk factors in eight patients (8, 57.1%). Birth asphyxia was present in nine neonates (9, 13.6%) in a high-risk group (n = 65) and a severe- risk group (n2=14), and birth asphyxia was present in five neonates (5, 35.7%). Based on the outcome, in high-risk pregnancy (n=85), four neonates (4, 4.5%) died and in severe-risk pregnancy (n=15), one (1, 6.3%) died. Conclusion: The study found various obstetric complications and outcomes associated with high-risk and severe-risk pregnancies. The results indicated a significantly higher proportion of caesarean sections performed in severe-risk pregnancies compared to high-risk pregnancies. Moreover, the overall outcome was favorable, with only five neonatal deaths reported among the one hundred maternal risk groups.

Background: Ovarian cancer is the eighth most frequent cancer among women worldwide, accounting for 4% of all cancers in the female population. When compared to other reproductive system cancers, ovarian cancer has a high death and morbidity rate. Objectives: The aim of the study was to assess the clinical presentation and histological types of ovarian tumor in patients admitted in tertiary care center. Methods: A descriptive cross-sectional study was conducted to determine the clinical presentation and histopathological types of ovarian tumour diagnosed at Medical college for women, Uttara and Nightingale medical college, Ashulia. The study was approved by the Institutional Review Board (IRB) and 600 patients diagnosed with ovarian tumors were consecutively included in the study from July 2009 to August 2016. The cases were diagnosed and subclassified in accordance with the WHO Classification of Female Genital Tumours, Fourth Edition. Statistical Package for Social Sciences (SPSS) application, version 25, was used for data analysis. Results: Out of Total Gynaecological admission of 4800 patients during the study period, 600 patients were admitted with diagnosis of ovarian Tumor, So occurance was 12.5%. the mean age of the patients was 35 ± 2.09. About 8.6% of the patients had less than 20 years old. 56.6% were within the age group of 21-40, 29.8% were within the age group of 41-60 and only 5% had more than 60 years. The mean Menarche in years was 14.6 ± 1.02 and Menopause in years was 48.7 ± 2.46. Regarding clinical presentation 37.40% had abdominal pain, 55.50% had abdominal mass, 3% had abdominal distension,2% had ascites, 0.50% had menstrual irregularities and 2.50% were asymptomatic. Regarding surgical procedure, 35% undergone Total abdominal hysterectomy and bilateral salpingo-oophorectomy, 18.33% Bilateral salpingo-oophorectomy, 15% Right salpingo-oophorectomy and Left salpingo-oophorectomy recommendation, 13.33% Right cystectomy, 3.33% Left cystectomy. Regarding consistency of tumour 57.33% were cystic, 37% were solid, 5.33% were complex and 0.33% were Diffuse pattern (metastatic tumor). Benign tumors were 77%, borderline 16.67% and malignant 6.33% cases. Out of 462 benign tumors, Serous cystadenoma (230/49.78%), Mucinous cystadenoma (60/12.98%), benign Brenner tumor (10/2.16%), Mature cystic teratoma (110/23.80%), stroma ovarii (10/2.16%), Fibroma (10/2.16%), Fibro-thecoma (12/ 2.59%), leiomyoma (20/4.34%). Out of 38 malignant tumour, Serous cystadenocarcinoma (11/28.94%), mucinous cystadenocarcinoma (6/15.78%), clear cell carcinoma (1/2.63%), Malignant Brenner tumor (1/2.63%), endometroid adenocarcinoma (4/10.52%), squamous cell carcinoma arising in mature teratoma (1/2.63%), Dysgerminoma (7/18.4%), Immature teratoma (1/2.63%), malignant mixed germ cell tumor (1/2.63%), Adult granulosa cell tumor (4/10.52%), Krukenburg tumor (1/2.63%). Survival status was satisfactory; 99.67% patients was alive. Conclusion: The study found that ovarian neoplasms had ambiguous signs and symptoms, were mostly seen in reproductive age groups, and were mostly benign. The proportion of malignant ovarian neoplasms was significantly lower than that of benign ovarian neoplasms. Although incidence of malignant tumor is less common but gynocologists should be more careful in diagnosis of malignancy as ovaries are pelvic organs and definite screening methods are not available and malignancy can occur in any age.

Background: Hypertensive disorders during pregnancy, including gestational hypertension and preeclampsia, can lead to adverse outcomes for both the mother and the baby. Exploring the perinatal outcomes of pregnant women with hypertensive disorders is crucial for improving maternal and neonatal health. Aim of the study: This study aimed to assess the perinatal outcomes of pregnant women with hypertensive disorders. Methods: This cross-sectional study was conducted at the Department of Gynecology & Obstetrics, 250 Bed General Hospital, Meherpur, Bangladesh from January 2021 to December 2021. A total of 87 pregnant women with hypertensive disorders were enrolled in this study as the study subjects purposively. For data analysis, MS Office tools were used. Results: In this study, the majority of participants underwent cesarean delivery (55%), with 38% having a normal vaginal delivery, and 7% undergoing instrumental delivery. Maternal complications included HELLP (Hemolysis, elevated liver enzymes, and low platelets) syndrome in 18% of cases, abruption placenta in 8%, and pulmonary embolism in 6%. Normal perinatal outcomes were observed in 51% of cases, while 26% experienced preterm birth, 15% had low birth weight, 6% resulted in stillbirth, and 2% led to intrauterine fetal death (IUFD). Conclusion: By administering appropriate interventions, the incidence of cesarean delivery may be reduced in pregnant women with hypertensive disorders. Physicians are strongly encouraged to pay special attention to prevent HELLP (Hemolysis, elevated liver enzymes, and low platelets) syndrome in these cases.