Midline cerebral congenital malformations, despite their relative rarity in the general population, with their high rate of Introduction: Postmenopausal bleeding is frequent in gynecology and occurs approximately in 5% to 10% of postmenopausal women. But most of the causes of post-menopausal bleeding are benign and treated conservatively. Women with postmenopausal bleeding have a primary or secondary malignancy of about 10%. So before starting treatment malignancy must be excluded. Common malignancies among them are endometrial or cervical carcinoma and rarely, ovarian cancer. The incidence of malignancy in the postmenopausal period remains sufficiently high, so it requires immediate investigations for early diagnosis, prompt treatment, and vigilant follow-up. The objective of the study is to evaluate the causes of postmenopausal bleeding in tertiary care hospitals in Dhaka city. Methods: This retrospective study was conducted at the Department of Obstetrics and Gynecology in Delta Medical College and Hospital, Dhaka, Bangladesh. The study duration spanned 12 months from July 2022 to June 2023. The study population consisted of 72 patients who presented with postmenopausal bleeding. The sampling for this study was conducted using a consecutive sampling method. Ethical approval was obtained from the ethical review committee of the study hospital. Descriptive statistics were used to summarize the demographic and clinical characteristics of the study participants. For the statistical analysis, the Statistical Package for the Social Sciences (SPSS). Results: Among 72 cases of postmenopausal bleeding, we found 9 cases of cancer (12.50%). Among them, 2 cases were cancer of the uterine cervix and 7 cases were cancer of the uterine corpus. Benign pathology was more frequent (63 cases: 87.50%), essentially presented atrophic endometritis 15 cases(20.83%), endometrial hyperplasia without atypia27.78% cases, endometrial polyp 16.67% cases, endocervical polyp 5.56% cases, cervical polyp 8.33%, leiomyoma found in 5.53% cases and preinvasive disease about 2.78% cases. Histopathological findings in 2 cases of carcinoma cervix were invasive squamous cell carcinoma and 7cases of endometrial cancer were endometrial adenocarcinoma. Cancer increased with advanced age while the incidence of bleeding decreased with age. Within 45 to 65 years of age is more frequent to develop post-menopausal bleeding. Conclusion: Even though causes of post-menopausal bleeding are mostly benign and treated conservatively but malignancy must be ruled out by endometrial and cervical biopsy.

Introduction: Preeclampsia, a dangerous condition characterized by high blood pressure during pregnancy, poses risks to both mothers and infants. Understanding the risk factors associated with preeclampsia is essential for effective prevention and management. This study aims to identify and investigate the potential risk factors contributing to preeclampsia in women, with the goal of improving the health outcomes of expectant mothers and their babies. Methods: This study was a case-control study conducted in the department of Obstetrics and Gynaecology at Dhaka Medical College Hospital (DMCH). The study period spans from 1st July 2019 to 31st December 2019. The study population consists of 100 participants, including 50 pregnant normotensive women as the control group and 50 pregnant women diagnosed with preeclampsia oreclampsia as the case group. The Ethical clearance of this study was obtained from the Institutional Review Board of Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. Results: Out of 100 patients, the control group consisted of 30% individuals aged 21-25 years, while the case group had 32% individuals aged 16-20 years. The mean age for the control group was 23.11 years (SD 5.9), and for the case group, it was 24.5 years (SD 6.3). The distribution of study patients based on risk factors reveals statistically significant differences between the control and case groups for the variable’s "gravidity" and "antenatal care" (p < 0.05). The case group had a higher proportion of primigravida (first-time pregnancy) and irregular or no antenatal care. However, no significant differences were observed for the variables "family history of hypertension" and "gestational age" (p > 0.05). In terms of clinical parameters, the case group exhibited significantly higher prevalence of proteinuria at all levels (1+, 2+, and 3+) compared to the control group. The blood pressure readings, both systolic and diastolic, were also significantly higher in the case group. Moreover, the case group had significantly lower serum calcium levels than the control group. These differences were statistically significant with p-values indicating p<0.01 o p< 0.001. Basis on the results the significant risks factors associated with Preeclampsia were observed, Gravidity (p=0.05), Antenatal care (p=0.05), Proteinuria (p=0.001), Blood Pressure-Systolic(mmHg)(p=0.001), Blood Pressuredystonic (mmHg) (p=0.001), Serum Calcium Level (mg/dl) (p=0.001). Conclusion: The study observed Gravidity, Antenatal care Proteinuria, Blood Pressure - Systolic (mmHg), Blood Pressure - dystonic (mmHg), Serum Calcium Level (mg/dl) were the significant factors associated with the Preeclamptic Women in Bangladesh.

Cerebral thrombophlebitis gravidopuerperale is a rare but serious pathology that can engage the maternal-fetal prognosis. It requires early diagnosis and treatment fast. Indeed, much rarer than arterial thromboses, thrombophlebitis are a significant cause of death and stroke. They can occur during pregnancy but most often they occur within a few days to a few months following postpartum. The frequency of peripartum cerebral thrombophlebitis is on average 1/3000 to 1/10000 births, but recently the number of cases recognized seems higher partly because of the more widespread knowledge of the variability of different forms of clinical presentations of cerebral venous thrombosis allowing a diagnosis, and on the other hand the wider use of imaging means more and more effective, in particular MRI. The objective of this study is to describe the epidemiological, clinical, paraclinical, therapeutic and evolutionary gravido -puerperal cerebral thrombophlebitis.

Introduction: Induced abortions are those terminated by deliberate action undertaken to terminate a pregnancy. Information on the incidence of induced abortion is crucial for identifying policy and programmatic needs aimed at reducing unintended pregnancy. Because unsafe abortion is a cause of maternal morbidity and mortality, measures of its incidence are also important. This study aimed to analyze the sociodemographic characteristics of induced abortion. Methods: A descriptive cross-sectional study was conducted at the Department of Obstetrics and Gynaecology, Dhaka Medical College Hospital, Dhaka, Bangladesh. The sample was composed of 50 women who underwent induced abortion in this hospital, between January 2022 and January 2023. A simple random sampling technique was used in this study. Data were collected using a data collection sheet, processed, and analyzed by SPSS. version 22. Data were presented in tables and pie charts. The study was approved by the Ethics Committee of Dhaka Medical College Hospital. Informed written consent was taken from the respondents. Result: In this study, most of the patients (25, 50%) were in the 25-30 years age group, followed by (18, 36%) 31-35 years age group, and (7, 14%) the rest were in >35 years age group, most people (30, 60%) resided in the urban areas and most of them (35, 70%) had a monthly income of <15000 BDT, followed by (10, 20%) 15000-20000 BDT. Respondents were mostly (25, 50%) uneducated, some of them (15, 30%) passed secondary school, and (10, 20%) higher secondary school. Most of the patients (18, 36%) in this study used the barrier method for contraception, followed by (16, 32%) withdrawal method. Regarding the cause of induced abortion, unplanned pregnancy was the prominent cause (16, 32%), followed by, inadequate income (12, 24%), and contraception failure (12, 24%). Conclusion: This study concluded that most of the patients aged between 25 to 30 years and most of them resided in urban areas having a low monthly income, and poor education level. Some prominent causes of induced abortion were unplanned pregnancy, inadequate income, and contraceptive failure.

Introduction: The pharmacologic agents currently used routinely to prevent postpartum hemorrhage are mainly oxytocin, syntometrine (a combination of oxytocin and ergometrine), and carbetocin. Syntometrine is associated with a statistically significant reduction in the risk of postpartum hemorrhage when compared with oxytocin alone. So, this study aimed to assess the adverse effects of carbetocin administration in the third stage of labor. This study aimed to analyze the adverse effects of carbetocin administration in the third stage of labor. Methods: This cross-sectional observational study was conducted at the Department of Obstetrics and Gynaecology, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh. The study period was from May 2016 to October 2016. 100 women undergoing normal vaginal delivery were the study subject. A convenient sampling technique was used in this study. Necessary data was collected in the data collection sheet. Women received a bolus of 100 microgram carbetocin IV at delivery of the anterior shoulder. A standardized deliver mat (Quaiyum's mat) was used before placental removal for measuring blood loss. Statistical analysis was carried out by using the Statistical Package for Social Sciences version 19.0 for Windows (SPSS Inc., Chicago, Illinois, USA). The mean values were calculated by frequencies and percentages. Result: In this study, the majority (54, 54.0%) of patients belonged to age 20-25 years, followed by (30, 30.0%) >25 years. It was observed that the majority 93(93.0%) patients had regular menstrual history. Concerning the clinical indices, anaemia was found 69(69.0%), jaundice 08(8.0%) and edema 24(24.0%). Additional uterotonices was used in 15(15.0%) and blood transfusion 07(7.0%) patients. Mean blood loss before the use of the weight of Q-mat was found 74.81±1.23 gram, mean blood loss after the use of the weight of Q-mat was 246.28±99.98 gram, and mean net blood loss was 141.61±59.93 gram. Majority 61(61.0%) babies had birth weight ≥2.5 kg. Majority 68(68.0%) patients had Hb% <10.5. The mean Hb% before delivery was 10.3±0.47 gm/dl with a range from 9.40 to 11.20 gm/dl The mean birth weight was found 2.57±0.41 kg with a range from 2.3 to 3.10 kg. Conclusion: Carbetocin appears to be an effective new drug in the active management of third-stage labor. Carbetocin has associated with a lower risk of various adverse effects and preventing postpartum hemorrhage in women undergoing vaginal delivery.

Objective: Ovarian cancer is a leading cause of gynecological cancer death among women worldwide. Silent growth of the tumor and challenges associated with preoperative evaluation of an ovarian mass are responsible for late presentation. The aim of this study was to evaluate the association between preoperative neutrophil to lymphocyte ratio (NLR) and epithelial ovarian tumor. Methods: A total of 60 patients diagnosed with ovarian tumor who fulfilled the selection criteria were recruited as study population. The ovarian tumor was subsequently diagnosed by histopathological analysis as either malignant epithelial ovarian tumor or benign epithelial ovarian tumor. Preoperative demographic and laboratory variables are reviewed in all patients. Association of preoperative NLR was assessed in benign and malignant epithelial ovarian tumor using unpaired t test. Receiver operating characteristics curve was used to calculate optimal cut off value for NLR to predict ovarian cancer preoperatively. A p-value of <0.05 was considered to indicate statistically significant differences. Results: There was statistically significant difference between the groups in terms of age, menopausal status, and NLR (all p=0.001, except for menopausal status p=0.007). NLR value was significantly higher (3.47±1.52) in patients with malignant ovarian tumor (p=0.001) than that of benign ovarian tumor. Higher NLR value predicted ovarian cancer at the cut-off value of 2.78, with 75.6% sensitivity and 78.9% specificity (95% CI, 0.97-1.0). Conclusion: Malignant epithelial ovarian tumor is associated with higher NLR. Preoperative NLR may be helpful for prediction of malignant ovarian tumor.