Malignant diseases are considered one of the problems of our time, and cancer is defined as the abnormal growth of malignant cells. It is widely accepted as the leading cause of death. There is currently no proven cancer cure. As a result, scientists have concentrated on creating secure and efficient therapies. Research has been done on the effects of naturally occurring substances that have been extracted from living things, such fungus on cancer cells. This study sought to determine the natural products' efficacy against human cancer cell line MCF-7. After A. terreus was isolated from samples of chicken droppings, it was grown on potato and Sabouraud Dextrose Agars (SDA and PDA) with chloramphenicol media. It was then identified using the extracted genomic DNA, the internal transcribed spacer (ITS) region was amplified and sequenced. After 30 days of incubation at 27°C, natural metabolite products were also recovered from the fermentation medium using the ethyl acetate extraction technique. The effectiveness of the fungal extract against the human cancer cell line MCF-7 and the normal human cell line NHF cell was also determined after incubation for 27 hours with the natural extract. The treated human cancer cell line MCF-7 showed decrease of proliferation, whereas the normal human cell line NHF showed no effect. Significant inhibitor compared to cancer line. The IC50 values for MCF-7 cell lines and NHF normal human cell lines were 7.672 and 1431 μg/mL, respectively. In summary, MCF-7 was affected by the natural extract extracted from A. terreus, in contrast to the control. When these results were combined, they showed that the fungal extract is an effective anti-cancer treatment.

Industrially, starch is obtained from cereal grains such as wheat and maize (corn), or from tubers, such as potatoes, tapioca, and arrowroot, or from the pith of the sago plant. By far, the larger part of the starch is obtained from maize, wheat, potato, and tapioca. Starch is present in almost all the tissue such as leaves, roots, tubers, seeds, stems, flowers, etc. of green plants however there are some plants which are grown commercially for the starch which includes cereal such as wheat, corn, sorghum, and rice, tuber mainly potato, root like tapioca and arrowroot, stem of sago, and legume crops mainly pea. Worldwide production of an overview on applications of starch 142 starch is depending on the use of cereals as the raw materials. Normally starch from Conventional sources of starch include sources like cereal corps and legume seeds, tuber crops, and some root tubers is used in large amount in the field of pharmacy. Due to unbelievable increasing demand for starch some nonconventional starch resources have been investigated in recent Years.