The search for dietary sources with potent biological activities has increasingly attracted considerable attention. Sweet potato leaves (SPL) are considered to be a leafy vegetable consumed by humans, which is not currently widely used, despite it possession drought tolerance, and the ability to grow in different climates and farming systems. This study evaluated the in vitro Nutraceutical and Pharmacological potential of underutilized leafy vegetable (Ipomoea batatas leaf). The phytochemicals, in vitro antioxidant and anti-inflammatory activities; mineral and vitamins compositions of the leaf were carried out using standard method. The bioactive compounds in Ipomoea batatas were identified using GC-MS. The results of the GC-MS profiling revealed n-Hexadecanoic acid (23.43%), Cyclotrisiloxane, hexamethyl (17.73%), and 16-Pregnenolone (11.30%) as the most abundant bioactive compounds in Ipomoea batata leaves. The mineral analysis showed that Ipomoea batata leaves contains favorable amount of macro elements such as Ca (915.40±9.50), K (2083.30±15.00), P (511.26±4.70), Mg (271.25±7.20), Na (9.98±1.06) and considerable amount of trace elements such as Fe (10.60±1.30), Mn (2.55±0.27), Zinc (2.70±0.11), and Cu (1.32±0.08) in which all were measured in miligram per 100g (mg/100). The vitamins such as of Vitamin A, vitamins C, vitamin E, niacin (B3), thiamine (B1), riboflavin (B2), pyridoxine (B6), vitamin D and vitamin K are present in trace amount in the leaves. The in vitro antioxidant activities of the extract showed a significant (p<0.05) dose dependent free radical scavenging activities. The anti-inflammatory analysis showed that the percent inhibition of hemolysis (20–100 µg/mL dry weight basis) was within the range of 4.1% to 18%. Percent inhibition of protein denaturation was within the range of 29.0–71.0%, Proteinase inhibitory activity was within the range of 16–30.0% and the lipoxygenase inhibition was within the range of 8.2–34.5%. This study provide validation for the usage of Ipomoea batatas leaf as new leafy vegetable with appreciable nutritional values and also provided credence to the bioactive compounds in leaf as potential novel drug candidate for pharmaceutical industries.

The majority of the world population prepares medicines from plants to cure diseases. Schinus molle linens is a multipurpose plant that has been used for various remedies as constituents of traditional medicine. The aim of this study was to investigate the chemical constituents and antimicrobial activity of methanol extract and solvent fraction extracts of the stem bark of Schinus molle. Powder of Schinus molle was extracted with methanol by using the maceration method and the fractions were obtained by successive fractionation of the methanol extract with n-hexane, chloroform, ethyl acetate, and n-butanol. Preliminary phytochemical analysis of the crude methanol extract revealed the presence of flavonoids, terpenes, anthraquinones, alkaloids, tannins, phenols, and saponins. In addition to this, the antimicrobial activity of crude and solvent fraction extract was tested against S. aureus, E. faecalis, E. coli, and C. albicans at a concentration of 90.0, 180.0, and 900.0 μg/ mL. The crude methanol extract and chloroform fraction exhibited greater activity against gram-positive, gram-negative bacteria and fungi. The n-hexane and n-butanol fractions showed the least activity against most test bacteria and fungi. The study showed that it is possible to inhibit the growth of bacteria and fungi at different concentrations.