ORIGINAL RESEARCH ARTICLE | Jan. 25, 2019
Stress and Obesity in Health Professional Students: Myth or Reality
Trushna Shah, Geetanjali Purohit, Swapan Goswami
Page no 1-4 |
10.36348/sijb.2019.v02i01.001
Background: Stress is a negative emotional, cognitive, behavioral and physiological process occurs as individual adjusts with stressors. Stress-induced eating may be one of the factors that leads to obesity due to increased calorie intake, associated with excess cortisol secretion. Present study aimed to assess the level of perceived stress and its association with BMI in health professional beginners. The objectives were to assess the level of stress by pre-validated perceived stress scale and the relationship between stress and obesity in first year health professional students. Material and Methods: A cross sectional study was conducted in the Department of Biochemistry, SBKS MI & RC, SVDU for consecutive two batches 2016-17 & 2017-18. Total 506 first year MBBS, BDS & BPT students were studied for age, gender and demographic parameters as weight, height & BMI. Stress was assessed by PSS-10 scale. Two groups were identified as their PSS score, stressed and non-stressed. Results: PSS score showed that among all participants 71.74% (N=363) students were stressed and 28.26% (N=143) students were non stressed. Out of 506 students 151 (approx 30%) students were having above normal BMI. BMI & PSS score showed significant association (X2, p <0.05). PSS score found to be significantly more when compared for overweight and obese categories than Normal and underweight. Conclusion: The significant association between stress level and increasing BMI shows that prompt measures should be taken to control obesity in young health professionals to control the stress and anxiety also to prevent the occurrence of life‑threatening diseases such as diabetes and hypertension.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2019
Anthropometric Indices, Inflammatory & Oxidative Stress Markers in Metabolic Syndrome
Deepthy C Sahadevan, Busi Karunanand, D. K Sharma
Page no 5-8 |
10.36348/sijb.2019.v02i01.002
The present study was undertaken to investigate the variations of anthropometric indices, inflammatory oxidative stress and anti-oxidant markers in subjects with metabolic syndrome (MetS) compared to their age & sex-matched controls, and to evaluate the correlations, if any of the anthropometric indices with the pro-oxidant state in subjects with MetS. One hundred and fifty-three subjects with MetS and one hundred and fifty-five controls were recruited for the study according to the NCEP ATP III (National cholesterol education program – Adult treatment panel III) criteria for MetS. Anthropometric characteristics of all subjects were recorded using clinical Proforma. Blood samples were collected after taking informed written consent from subjects. Plasma glucose, lipid profile analysis, malondialdehyde (MDA), total antioxidant capacity and C reactive protein (CRP) was estimated in all blood samples. This study clearly indicates that obesity measured by anthropometric measurements including BMI and WC were increased in MetS patients as compared to controls. Inflammatory marker CRP was found to be significantly high in patients with metabolic syndrome. The oxidative stress as assessed by serum MDA was significantly higher, whereas total antioxidant capacity (TAOC) was lower in MetS patients than that of age & sex matched controls
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2019
A study of Association between Thyroid Profile and Glycated Haemoglobin in Patients with Type II Diabetes Mellitus
Aruna Tushar Sharma, Gaurang Kishorbhai A, N. Haridas
Page no 9-14 |
10.36348/sijb.2019.v02i01.003
Diabetes mellitus and thyroid diseases are the two most common endocrinopathies encountered in clinical practice. Thyroid hormone abnormalities are frequently associated with diabetes and remain unidentified. Thyroid dysfunction could negatively impact Diabetes and its complications. Thyroid hormone replacement is associated with a decrease in Glycated Hemoglobin (HbA1c) level. The present study was undertaken to study association between thyroid profile and glycated Haemoglobin (HbA1c) in Type 2 Diabetes Mellitus patients. A case control study was done at Shri Krishna Hospital in Karamsad city .100 cases of Type 2 Diabetes mellitus and 100 healthy controls were taken. Blood samples were collected and analyzed for thyroid profile, HbA1c, Fasting Blood Sugar and Renal Function Test. We found that there was a positive correlation between TSH (Thyroid stimulating hormone) and HbA1c levels, and a negative correlation between Thyroid hormones [Triiodothyronine (T3) & Thyroxine (T4)] and Glycated Haemoglobin (HbA1c) in cases of type 2 Diabetes Mellitus. There is a significant decrease in TT3 (Total Triiodothyronine) and TT4 (Total Thyroxine) and significantly increased TSH in cases of Diabetes mellitus as compare to healthy Controls. We found that out of 100 cases of type 2 Diabetes Mellitus, 31% patients showed thyroid disorders. There is a high prevalence of thyroid disorders in Diabetic patients. If not diagnosed early, it could negatively affect diabetes and its complications. Therefore, routine screening of thyroid profile in diabetic patients is advisable to improve quality of life and reduce morbidity rate.