REVIEW ARTICLE | May 7, 2022
Alimentary and Recuperative Prospective of Curcuma longa (Turmeric)
Umar Rehman, Qamar Abbas Syed, Hafiza Anam Asghar, Muhammad Kamran Arshad, Ghayyor Sultan, Azeem Asghar, Mueez Aslam, Muhammad Abdullah
Page no 67-75
Plant based traditional health care is one of the ancient remedies used to prevent and treat different health related disorders. Due to increasing cost of medicine in the modern era, people are now moving towards the utilization of ancient ethno medicinal plants based remedies to prevent and treat diseases as well as to maintain their health. Curcuma longa, commonly known as turmeric has been used since ancient times as ethno medicinal plant due to its pharmacological and therapeutic potential. The rhizome of this plant is commonly used to prevent the lifestyle related disorders. Its biologically active components can also be extracted and utilized directly to enhance the efficacy. Purpose of this review is to highlight the importance of turmeric as it contains various biologically active components that are beneficial in prevention and treatment of various health related disorders. Turmeric has been demonstrated to exhibit anti-cancer, immunostimulant, skin protection, ulcer treating, anti-inflammatory, anti-malarial, anti-bacterial, anti-fungal, anti-viral, anti-parasitic, anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, hepatoprotective, renal protection and hematological parameters maintenance properties. There is no evidence of adverse effects of turmeric in literature. Only the people who are allergic to it can have side effects otherwise it is almost stomach friendly due to which it can be used for treatment of various health related disorders.
ORIGINAL RESEARCH ARTICLE | May 7, 2022
Impact of Inflammatory Markers in Predicting Outcomes of SARS-CoV-2 Patients: The why’s and how’s of Diabetic Hypertensive Patients
Dr. Ganesh P, Amina SA, Dr. Ismail HM, Drisya Kaladharan, Dr. Shaheen B Shaikh
Page no 76-80
Background: Hypertension and Diabetes Mellitus, the most frequent co-morbidities in SARS-Cov-2 patients are considered as risk factors for disease severity and mortality. And the role of inflammatory biomarkers on these patients is still under evaluation. Methods: Retrospective data was collected study in 3 independent groups each with 24 patients: diabetes, hypertension and with concomitant diabetes and hypertension respectively of critically ill SARS-CoV-2 patients admitted in the CCM. The data of age, gender, diabetic and hypertensive history, inflammatory marker, duration of stay was obtained from electronic patient data repository of the hospital and compared with Mortality. Results: The mean CRP levels in diabetes was 78.81 ± 16.8, in hypertension 82.23 ± 13.98 and in group with both the co morbidities was 79.05 ± 16.38. Serum ferritin levels were high in hypertensive group 731 ± 621.12, were as in diabetes population it was 560.31 ± 319.81, and 629.37 ± 350.8 in both diabetic and hypertensive population. The mean and SD of D-dimer it was 3726.4 ± 2411.86 in diabetic group, 2861.28 ± 2041.36 in hypertensive group and 2755.6 ± 1980.67. CRP levels and D-dimer were positively correlated with mortality and duration of stay. Conclusion: Our study concluded inflammatory markers CRP and D-dimer levels were elevated in both comorbid patients and this was statistically significant. Correlation of ferritin to the outcome was not significant and understanding the molecular mechanism of infection in co-morbid patients and assessing the inflammatory markers can provide necessary assistance at earliest, for a better clinical outcome.