Aims & Objectives: To study the prevalence, number, location and variations of parietal foramen in human skulls and correlate with the clinical significance if any. Material and Methods: A total of 45 skulls with 90 parietal bones were studied in the Department of Anatomy Govt medical college Mahabubnagar from osteology specimens in the academic year 2018-2019.Various parameters like unilateral or bilateral occurance or total absence of the parietal foramen, their location in relation to sagittal suture and lambda, their shape have been observed using appropriate tools and the findings have been tabulate. Observation & Conclusions: Out of total 45 skulls there were 64 parietal foramina in 90 parietal bones, with foramina only on right side in 10 skulls, only on left side in 7 skulls, bilaterally present in 23 skulls, total absence in 4 skulls and 1 foramen located in the sagittal suture. Right foramen is at a mean distance of 0.58+/-3.6mm from sagittal suture & left is at 0.54+/-3.7mm from sagittal suture. Only 1 foramen was more close to lambda, rest (63) are at the junction of anterior 2/3rd & posterior 1/3rd of sagittal suture. Shape of 18 foramina were Circular, 10 were Slit like and the rest 36 were Oval.