ORIGINAL RESEARCH ARTICLE | Oct. 11, 2024
Effects of Smoothies on Oxidative Stress Markers Following Administration of Monosodium Glutamate in Male Wistar Rats
Gbaranor K. B., Maakai B., Olatunbosun T. H., Ben E. E., Otobo B. M., Enebeli K. S., Saronee F., Etim D. N., Ovili-Odili B.Z., Daka I. R.
Page no 129-134 |
DOI: https://doi.org/10.36348/sijap.2024.v07i08.001
Fruits are medicinal and also contain essential phytonutrients that gives the fruits potency that keeps the body healthy. The aim of the study is to ascertain the Effects of Smoothies (banana, apple and pineapple) on Oxidative Stress Markers following administration of monosodium glutamate in Male Wistar Rats. Thirty (30) animals weighing 130kg to 180kg were randomly selected into 6 groups with 5 animals per group. Group 1 received 5mls of distilled water, group 2 received 1ml/kg (low dose) of smoothies, group 3 received 2ml/kg (medium dose), group 4 received 3ml/kg (high dose), group 5 received 400mg/kg of monosodium glutamate, group 6 received 400mg/kg of monosodium glutamate and 3ml/kg (high dose) of smoothies co-administered. Administration was carried out for 14 days and on the 15th day, the animals were sacrificed, semen was harvested and 5ml blood was collected via cardiac puncture. Statistical analysis was done using ANOVA and expressed as MeanĀ±SEM. Statistically P < 0.05 was said to be significant. SPSS version 26 was used. The results showed significant increase in SOD in the group that was administered smoothies (high dose) and decrease in the group that was administered 400mg of monosodium glutamate (MSG). MDA increases in the groups that was administered MSG alone and when co-administered with smoothies (high dose). MDA also decreases in the groups given medium and high dose smoothies. Catalase decrease in the group that was given MSG alone. Gluthione increases in the groups that was given medium and high dose smoothies and decrease in the group that was given MSG only.
ORIGINAL RESEARCH ARTICLE | Oct. 21, 2024
Morphometry of Typical Cervical Vertebrae on Magnetic Resonance Imaging in Adult Bangladeshi People: A Cross-sectional Analytical Study
Maria Khan, Mousomi Tahmina, Kaniz Fatima, Nazia Binte Islam, Isot Jahan, Nafrina Islam Leeza
Page no 135-140 |
DOI: https://doi.org/10.36348/sijap.2024.v07i08.002
Background: Accurate knowledge of cervical vertebral morphometry is crucial for diagnosing pathological conditions and planning surgical interventions. However, data specific to the Bangladeshi population is lacking. Objectives: To determine the morphometric measurements of typical cervical vertebrae (C3-C6) on Magnetic Resonance Imaging (MRI) in adult Bangladeshi people and to analyze potential sex-based differences. Methods: This cross-sectional analytical study was conducted on 70 MRI scans (35 male, 35 female) of typical cervical vertebrae from adult Bangladeshi individuals. Various morphometric parameters were measured using 'Radiant DICOM Viewer' software. Statistical analysis was performed using SPSS version 22.0. Results: The sagittal diameter of the vertebral body was significantly larger in males compared to females for all measured vertebrae (p<0.001). No significant differences were found between sexes in the height and transverse length of the vertebral body, anteroposterior and transverse lengths of the vertebral foramen, dimensions of foramen transversarium, superior articular facets, lamina, pedicle, and spinous process length (p>0.05 for all). Conclusion: This study provides baseline morphometric data for typical cervical vertebrae in adult Bangladeshi individuals. The observed sexual dimorphism in sagittal vertebral body diameter and the lack of significant differences in other parameters contribute to our understanding of population-specific cervical spine anatomy. These findings may have implications for optimizing surgical techniques and implant designs for the Bangladeshi population.