The mode of locomotion of humans and primates leads to changes in their skeleton. Objective: Establish a link between the morphology of the tibia and the locomotive function from a comparative anatomical study between the tibias of bipeds, Homo Sapiens (HS) and Pan troglodytes verus (PTV), and of quadrupeds, Canis lupus familiaris (CLF) and Sus scrofadomesticus (SSD). Materials and methods: It concerned an analytical and comparative study by direct observation involving a sample of 52 tibias. We proceeded by direct observation, to a synthetic analysis of the morphological characteristics of the tibia that we compared in bipeds and in quadrupeds. Results: The tibial diaphyses of HS and PTV presented the same morphological conformation with an italic S aspect in HS and a varus aspect in PTV. With CLF and SSD, they are straighter and the different faces are distributed differently. The proximal epiphyses are voluminous and massive in both classes. In quadrupeds, they present upper tibial articular surfaces which are deformed backwards and a voluminous anterior tibial tuberosity. The distal epiphyses in quadrupeds are convex with more pronounced creases. Conclusion: This comparative study allowed us to demonstrate that the locomotive function has a significant impact on the morphology of the tibia.

The purpose of this study is to investigate the effects of the ethanolic extract of Persea americana (avocado) on the haematological parameters of male Wistar rats. The rats were randomly divided into three groups of five rats each. They were treated with ethanolic extract of Persea americana (except the control group). Group 1 received distilled water, Group 2 received 200mg/kg of the extract and Group 3 received 400mg/kg of the extract. The administration was done for 21 days. At the end of the administration, the rats were sacrificed under chlorofoam aneaesthesia and blood samples obtained and sent to the laboratory for analysis. The statistical analysis was done using the Statistical Package for Social Sciences software version 21.0. The analysis of variance (ANOVA) test was used to compare means. There was a significant (p<0.5) increase in packed cell volume (PCV), red blood cell count (RBC) and haemoglobin (Hb) concentration. There was no significant change in platelet count, white blood cell count, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, mean corpuscular volume, neutrophils count, lymphocytes count, eosinophil and monocyte count, Result of the present study has shown that the ethanolic stem bark extract of Persea americana improved the red cell series and may be useful in treatment of anaemia because of its ability to cause a significant increase in PCV, RBC and Hb concentration.