REVIEW ARTICLE | March 13, 2022
Changing Art of Anatomy Illustrations
Yogesh Ashok Sontakke, Jakkula Akhil
Page no 55-58 |
10.36348/sijap.2022.v05i03.001
Anatomical illustrations have gradual changed since their inception. The pioneers of the field have initially used pencil drawings, followed by line illustrations, colored illustrations, two dimensional and three-dimensional illustrations, and it grew up to virtual reality. Recent studies have observed their benefit in teaching anatomy, especially for providing spatial orientation of various structures and complex topics such as middle ear, pterygopalatine fossa, where dissection cannot offer much comprehension. Drawing software such as Illustrator and Photoshop have revolutionized the image quality in anatomy textbooks. Adobe Illustrator comprises many useful tools to draw anatomical diagrams such as pen tool, pencil tool, paint brush tool, text tool. It has various paper sizes to choose and different formats of files to create vector-based images. The drawing hardware such as Wacom Cintiq, Apple iPad Pro with pencil enhances the experience with drawing software.
ORIGINAL RESEARCH ARTICLE | March 16, 2022
Effects of Moringa oliefera Lam. Aqueous Root Extract on the Histology of Pancreas in Alloxan-Induced Diabetic Rats
Hashim BA, Ayuba Y
Page no 59-64 |
10.36348/sijap.2022.v05i03.002
This study was to determine the effects of aqueous root extract of Moringa oleifera on antioxidant activities and on the histology of pancreas in Alloxan-induced-diabetic rats. Twenty Albino Wistar rats of both sexes weighing between100 and 194g were used for the study. The animals were divided in to four groups (Groups I, II, II and IV) of five rats each. Group I was the control group and were administered distilled water per body weight. Group II was induced with diabetes by injecting the rats with 150mg/kg Alloxan single dose and not treated. group III was induced with diabetes and treated with 50mg/kg Moringa for 28 days and group IV were not induced with diabetes but were treated with the aqueous extract of Moringa oleifera root for a period of twenty-eight days at 50mg/kg orally. The antioxidant activity of Moringa oliefera aqueous root extract was studied by assaying serum marker substances of Catalase, Glutathione peroxidase (GPx), Superoxide Dismutase (SOD) and Malondialdehyde (MDA) to determine the extent of antioxidant activity of the extract on the pancreas. At the end of the experiment, the animals were sacrificed and the Pancreas processed for routing light microscopic analyses. The results of this study showed that antioxidant activities of Malondialdehyde (MDA) decreased significantly in diabetic not treated and diabetic treated Moringa groups and Glutathione peroxidase (GPx), activity increased significantly in diabetic non-treated group and non-diabetic treated group (p<0.05). Glutathione Superoxide Dismutase (SOD) and Catalase changes were not significant. The results of this study also showed that photomicrograph of pancreas of diabetic non treated rats showed highly lobulated pancreatic tissue, glands exhibits loose collagenous capsule which can be seen extending as delicate septae, chronic inflammation and degeneration of islets of Langerhans. Diabetic treated group also showed septea between the lobule similar to the control group and glandular acini undergoing regeneration. Non-diabetic but treated group showed diffused micro and macro acini and normal islets of Langerhans similar to control.
ORIGINAL RESEARCH ARTICLE | March 30, 2022
Ameliorative Potentials of Vitamin C against Inhaled Dichlorvos Lung Toxicity of Wistar Rats
Josiah Soipiriala Hart, Lekpa Kingdom David, Oghenefego Michael Adheke
Page no 65-69 |
10.36348/sijap.2022.v05i03.003
Introduction: Dichlorvos (DDVP), an active ingredient of Sniper insecticide, is commonly used in Nigeria to control insects by killing them thereby preventing the spread of diseases. However, it can be highly toxic to humans when inhaled into the respiratory system which could elicit oxidative stress and cause respiratory infections. Vitamin C is known to be an anti-oxidant, capable of inhibiting oxidative stress. This study was aimed at investigating the ameliorating effect of vitamin C on dichlorvos-induced toxicity of the rat lung. Materials and methods: Forty (40) male wistar rats (weighing 150 – 200g) were recruited and randomly grouped into five (5) groups of eight (8) rats each. A group was the control; two groups were exposed to graded concentrations of DDVP while the last two groups were treated with vitamin C. Body weights were obtained before and after the period of 21-day exposure. After 21 days, histopathological and biochemical analysis were carried out to examine the level of toxicity of DDVP and effect of vitamin C treatment on the lung tissues. Results: Rat groups treated using vitamin C administration had significant improvements in body weights compared to DDVP-exposed groups. MDA levels as well as CATA and SOD activities increased significantly on vitamin C-treated rat groups (p < 0.05). Post treatment of rat groups with vitamin C showed that the lung histoarchitecture significantly improved. Conclusion: It can be concluded that Vitamin C could be a supplementary remedy in organophosphate (dichlorvos) poisoning through inhalation.
REVIEW ARTICLE | March 30, 2022
Embalming with Formalin – Benefits and Pitfalls
Pal A. K, Bhanarkar U. P, Ray B
Page no 70-77 |
10.36348/sijap.2022.v05i03.004
Formalin is the most widely used preservative in anatomical embalming. It produces consistent results in terms of the prevention of autolysis and putrefaction at an affordable cost. It is a known carcinogen having several health hazards. Strict adherence to safety protocols is required to minimize its toxic effects. Regular monitoring of formaldehyde concentration in the dissection hall and embalming room will ensure remedial measures at the earliest. In the face of growing health concerns, several alternative preservatives are being studied. Apart from it, methods like cryopreservation, plastination can be used instead of embalming. Post-mortem toxicological analysis of formalin-fixed cadavers is of importance for forensic investigation. This article will review the overall advantages and disadvantages of formalin and its alternatives in the process of embalming and will guide the anatomists in choosing the proper options for the purpose.