Abstract: We report on a 12-year-old Saudi girl with uncontrolled congenital hypothyroidism, due to thyroid gland aplasia. She was found to have bilateral multicystic ovaries and menstrual dysfunction. This association is not widely recognized.

Abstract: We search for three non-zero distinct integers such that each of the triple (x-y, z, x+y) forms Harmonic progression. A few interesting properties among the solutions are also presented.

Abstract: The bi-quadratic equation with 4 unknowns given by x4 +y4+z4=32w4 is analyzed for its patterns of non-zero distinct integral solutions. Six different patterns of integer solutions to the above bi-quadratic equation are presented. A few interesting relations between the solutions and special numbers, namely, polygonal number and pyramidal number are exhibited.

Abstract: Albert Chinualumogu Achebe was best known for his portrayal of traditional African life as it clashes with white men (colonial masters). He was also known for his neglect of female characters’ role in most of his novels. In this paper, attempt has been made to show his ‘turn back’ from the earlier position of assigning women an inferior status in his novels. This is done in the light of Anthills of the Savannah where the dominant female character, Beatrice, is portrayed as a symbol of the new women – educated, full of potentials and credentials. Hence, Achebe with a new voice and thought. The paper concludes with explanation on the two sets of female characters in Achebe’s novels. The earlier novels reflected women as inferior and weak while in the novel analysed, the female characters represented by Beatrice, are portrayed with full potentials like their male counterparts. This is what makes the novelist a born-again.

Abstract: We search for non-zero distinct integer triples (a_0,a_1,a_2) such that each of the expressions a_0+a_1, a_0+a_2, a_1+a_2, 2(a_0+a_1+a_2) is a perfect square.

Abstract: We describe the case of a patient with Neurofibromatosis type 1 (NF1) and Secondary Hypertrophic Osteoarthropathy. On this association so far, hypertrophic osteoarthropathy seems to be related to the vascular involvement of Neurofibromatosis wherein some studies reveal release of PDGF (platelet derived growth factor) by the neural tumor.In order to exclude other causes of secondary Hypertrophic osteoarthropathy all possible causes were excluded.On the basis of clinical findings and exclusion of all other causes, and no literature or case reports suggestive of presence of Hypertrophic Osteoarthropathy in Neurofibromatosis type-1, this finding attains animportant clinching and rare clinical entity and also signifies to include one among the neurological causes of secondary Hypertrophic Osteoarthropathy. The possible pathophysiology of Hypertrophic Osteoarthropathy in patient with neurofibromatosis has been discussed.

Abstract: Marijuana induce alteration Hypothalamus and pituitary function and altered subsequently T3, T4 and TSH. To assess the Thyroid profile level(T3, T4, and TSH) in marijuana abuse .This case control study includes 120 Sudanese males (60 of them were marijuana abuse were considered as study group, and the other 60 healthy subjects were considered as control group ;were they do not use marijuana). All subjects were sex and age matched (age ranging between 18-60 years).Study group have addiction period between 1-37 years. This study carried in Alribatt hospital, Khartoum, from May to August 2015, serum was collected from both group and the concentration of T3, T4, and TSH were estimated using ELISA Bio TeK. There were a significant decrease in the level of the of T3, and TSH in marijuana abuse in comparsion with the control group where the (mean ± SD) was (1.25±1.77, 1.18±.69) for T3 and TSH respectively while the controls group had (mean ± SD) (1.04±.30, 1.91±1.21) for T3 and TSH respectively with p- value (0.00). But there was no significant difference in the level T4 when compared with the control group (9.99±4.16, 9.47±2.93) with p-value (0.19). This study concluded that T3 and TSH were highly significant decreased, but T4 were had insignificant change.

Abstract: Marijuana affects a variety of hormones that are regulated by hypothalamic function and it appears that the psychoactive ingredient, THC, is the major compound responsible for this action. To assess of LH, FSH, and Testosterone level in marijuana abuse. This case control study includes 60 marijuana abuses from Elribat hospital as case study. These patients are compared with age and sex matched with 60 healthy subjects as controls. All volunteers age ranging between 18-60 years. Blood samples were collected from all subjects, then serum concentration of LH, FSH, and testosterones were estimated using ELISA Bio TeK. There were a significant decrease in the level of LH, FSH and testosterone in marijuana abuse in comparison with a control group where the (mean ± SD) of LH, FSH, and Testosterone in marijuana abuse people were (4.9±1.9, 3.3±1.9, 19.3 ± 6.1) respectively while the (mean ± SD) of control group were (5.9±3.62, 6.9±3.6, 22.5±9.5) for LH, FSH, & Testosterone respectively. This study concluded that (LH, FSH and Testosterone) level were highly significant decreased in marijuana abuse.

Abstract: Tax non-compliance reduces tax collection and the tax performance within a country. The Kenyan government has implemented various strategies to bring businesses in the informal sector into the tax bracket. However, available data shows that tax collections from the informal sector are above average but on a declining trend. The purpose of this paper is to determine influence of tax rates on tax compliance in the informal sector in Nyeri town. The study adopted a cross-sectional survey design and targeted 715 informal businesses in Nyeri Town. Stratified random sampling technique was used to select 143 informal businesses to participate. Researcher-administered questionnaires were used to collect data from the respondents. Descriptive methods such as frequency distribution, percentages, mean, were used to summarize and organize data. Chi-square tests and correlation analysis were employed to establish relationships between study variables. Findings were presented using tables of frequencies and percentages. Majority (74%) of the respondents indicated that they tried their best to comply with all tax procedures. Results revealed that Majority (75%) of the respondents indicate that the taxes charged were too high. Tax rates (p=0.000) had a significant relationship with tax compliance at 95% confidence level. The study cited that tax rates were important predictors of tax compliance in the informal sector. It was recommended that tax rates should be reviewed for those in the informal sector to ensure that they commensurate with economic conditions.

Abstract: Glycyrriza glabra Linn.[ Fabaceae], commonly known as yashtimadhu, mulhatti, is used as medicine for treatment of various aliments in Traditional System of Medicine fairly throughout the greater part of India. In the present study, we have evaluated anticancer activity of Ammonium glycyrrhizinate by in vitro and in silico method. Ammonium glycyrrhizinate was isolated from roots of G.glabra and was characterized by solubility, melting point, infrared (IR) and thin layer chromotography (TLC) pattern. In vitro anticancer activity was done using HeLa cell lines by MTT assay at different concentrations ranging from 100-500 µg/ml using microtitre plate assays by ELISA and in silico docking studies using enzyme EGFR tyrosine kinase. The IC50 value was found to be 282.45 µg/ml in in vitro anticancer activity in HeLa cell lines. Ammonium glycyrrhizinate was subjected to molecular docking studies for the inhibition of the enzyme EGFR tyrosine kinase, which is one of the targets for inhibition of cancer cells. It has shown -11.03 kJ mol-1 binding and -12.47 kJ mol-1 docking energy with five hydrogen bonds. We can conclude that ammonium glycyrrhizinate has shown to possess anticancer activity both in vitro and in silico studies.

The purpose of this study was to develop a Interpenetrating Polymer Network (IPN) of Chitosan and Hydroxy Ethyl Cellulose (HEC). The drug Diltiazem HCl, used in the treatment of angina pectoris, hypertension and cardiac arrhythmia. Diltiazem HCl has a short elimination half-life; this will bring down its dosing frequency to once a day and on the same time make a zero order release system. Microspheres were prepared by using controlled release polymers. The formulations were evaluated for pharmacopoeial quality control tests and all the physical parameters evaluated were within the acceptable limits. Formulation B7 was proved to be good drug content, % drug encapsulation efficiency and % drug release up to 12 h as compared to the other formulations. Stability studies were carried out on the optimized formulation B7 for period of 3 months at 400c/75%RH. Finally it was observed that there was no change in physiochemical and physical properties as well as in drug release profile even after storage at 45°C and 75 % RH for three months.

Abstract: True hermaphrodite have gonads of both sex in the same individual. They contain ovary and testis with ambiguity of genital organs. We report a case of true hermaphrodite in a male patient of 26 years having absent of beard and moustaches, medium pitch voice , partial fusion of labia majora and testis, enlarged clitoris with non penile urethra, no vaginal and opening having uterus.

Abstract: An audit is an independent examination of account of an entity done by an independent auditor in other to ascertain the truth and fairness of the financial statement. This paper tries to explore the content of public and private audit in Nigeria. Various laws and enactment were view as what are the requirements of public as well as private audit. It was found out that both of them are two bird of the same feather. They are all governed by the professional pronouncement as well as the financial reporting standard of Nigeria. Although, but the parties maintain the code of ethics of the profession which include: Independence, Integrity, Confidentiality and professional duty and care. It was recommended that strengthening the independence of the supreme audit institution, and reinforcing the PAC to be alive to its responsibilities and improving the accounting environment. Also external audit should maintain the ethics of the institution toward rendering of their duties.

Abstract: Parovaraian cysts are simple cysts arising from the adnexa occurring most commonly in the women of reproductive age group. Rarely can they be of neoplastic origin. Female of 21 years presented with pain in abdomen. On basis of clinical examination, ultrasonography and biochemical tumour markers it was diagnosed as ovarian tumour. At laparotomy it was seen to be parovarian cyst of 12cm x 14cm size. On histopathology it was proved to be a neoplastic parovarian cyst - serous cystadenoma.

Abstract: Equality between men and women is a fundamental right and a common policy of many governments in the world today. Gender mainstreaming is the process whereby gender concerns are raised routinely within everyday operations of an institution or organization and resolved in a gender manner in normal operations. The well-being and the equality between men and women are addressed by gender mainstreaming. The purpose of this study was to establish the effectiveness of gender mainstreaming initiatives employed in enhancing gender equity in the Ministry of Agriculture, Livestock and Fisheries in Kirinyaga County, Kenya. The specific objectives of the study were to establish how recruitment and selection, employee awareness, a gender office and implementation of gender mainstreaming policy affect gender equity in Ministry of Agriculture, Livestock and Fisheries in Kirinyaga County. The study employed a descriptive survey research design and targeted all fifty (50) Ministry employees. Descriptive data analysis was done which generated mean and standard deviation with the help of Statistical Package for Social Sciences (SPSS). Frequencies and percentages were also generated. The study established that there was a close relationship in terms of proportions of the respondents between a yes (54%) and no (46%) responses on training.The study established that the Ministry ensured fair recruitment and selection based on Gender Equity to a great extent (36%).It is therefore recommended that the Ministry through their Cabinet Secretary provides statistics of the incoming employees based on gender. The researcher also recommends that the Ministry clearly outlines what constitutes gender mainstreaming training. The study also found out that the Ministry of Agriculture, Livestock and Fisheries had neither done much (40%) on sponsoring gender balance awareness training nor done much(34%) on implementing gender balance awareness training. The researcher therefore recommends that awareness training should be enhanced.