Background: Several studies all over the world have proposed the association of Papillary Thyroid Carcinoma with Hashimoto Thyroiditis, Lymphocytic Thyroiditis and Multinodular goitre. Papillary Thyroid Microcarcinoma (≤ 1cm size lesions) which are detected incidentally on histopathological examination of thyroidectomy specimens can progress to clinically evident Papillary Thyroid Carcinoma if left untreated. In this study, we aim to determine the types of lesions associated with Papillary Carcinoma Thyroid and to study the most commonly associated lesion, age group and gender affected. Materials and Methods: A total of 74 cases of Papillary Thyroid Carcinoma who underwent thyroidectomy at a tertiary care hospital in Kerala were included in the study. The association between types of lesions, age group and gender were studied and the data obtained was analyzed using Chi Square test. Results: Mean age of the study population was 47 years and majority were females (86.5%). Out of 74 cases of Papillary Thyroid Carcinoma, 58 cases (78%) had associated lesions. The most common associated lesion with Papillary Thyroid Carcinoma was Multinodular goitre (59%), followed by Lymphocytic Thyroiditis (50%) and Hashimoto Thyroiditis (16%).Among the 74 cases, 17 cases (23%) were of Papillary Thyroid Micro carcinoma. Conclusion: It was found that there was significant prevalence of associated lesions with Papillary Thyroid Carcinoma. Hence all non neoplastic lesions of thyroid which are usually managed conservatively require a strict follow up to rule out the possibility of developing Papillary Thyroid Carcinoma. This will go a long way in preventing the morbidity and mortality that could arise in Papillary Thyroid Carcinoma.

The diagnosis and treatment of oral premalignant lesions and squamous cell carcinoma are currently based on histopathologic features, site of involvement and stage of disease. Recent advances in techniques for detecting lesions and predicting their progression or recurrence are reviewed here. Adjuncts for detection of lesions and selection of biopsy sites include vital tissue staining (with toluidine blue) and exfoliative cytology. Advances in diagnosis and staging at the molecular level are expected to affect choice of treatment and patient outcomes. Oral health care providers should be aware of these advances in the evaluation and diagnosis of oral premalignant lesions and squamous cell carcinoma.

Intramedullary spinal schwannomas are rare tumours and are usually associated with neurofibromatosis types 1 and 2. Intramedullary spinal schwannomas without neurofibromatosis are very uncommon. These tumours may present with slowly progressing sensory or motor syndrome. We report a case of 50 years female patient presenting with Intramedullary spinal schwannoma at D11 to L1 levels.

This study concentrates on the theoretical and applied aspects of the contractual liability under the third parties act; the theoretical aspect of this liability includes the definition, conditions, the range, features, provisions, and legal basis. Additionally, the most important applications of this liability within Bahrain Civil Law is discussed: Construction contract, and Lease contract. The research defines contractual liability under the third party act as a contractual liability which will be held when the debtor uses a third party to implement his contractual commitments, as long as there are no contractual terms preventing this.

Human cysticercosis is caused by encysted larvae of Taenia solium. This parasitic disease is endemic in developing countries like India. Most frequent reported locations are skin, subcutaneous tissue, skeletal muscles, mucus membranes, heart, eye & CNS. Head & neck (excluding orbital & neurocysticercosis) is an uncommon location for cysticercosis. We reported a case of cysticercosis cervical swelling resembling cervical lymphadenopathy in a 25 years old female patient who presented with painless left cervical swelling. Clinical diagnosis considered was tubercular lymphadenitis. On microscopic examination excised tissue comprised of skeletal muscles with cysticercosis cellulosae. We reported this case of cysticercosis because of its unusual presentation as cervical swelling mimicking cervical lymphadenopathy. It is a preventable disease. Personal and household hygiene is very important. Histopathology is the reliable method for confirming the diagnosis.

This research at legal issues do General Principles of Good Governance stone behavior can be propagated as test corruption government politics village as the alternative solution build control mechanisms for corruption be able to control of the village head in village funds. This research method is a study of legal research. The results of this study the approach to applying AUPB as a test for village government corruption behavior by a judge can technically be done in 2 (two) ways, namely: through induction and deduction legal reasoning. Practical experience shows that the settlement of disputes in the Court so far usually begins with an induction step, which is in the form of formulating facts, seeking a causal relationship, and determining the probability. After the induction step, it is followed by efforts to apply the law as a step of deduction. In the application of law, it always begins with identification of legal rules. Efforts to identify the rule of law, often encounter conditions; legal vacuum (leemten in het recht), legal antinomy (conflict of norms), and vage norms.

Asymptomatic bacteriuria spans all age groups from neonates to elderly. It is much more common in boys during first three months often in association with urologic abnormalities. During preschool years it is common in girls than boys. Presence of bacteriuria in childhood defines a population at higher risk for development of bacteria in adulthood [1]. The present study was carried out in Department of Microbiology, in a tertiary care hospital, over a period of one year from Jan 2016 – Dec 2016. A total of 100 childrens of all age groups and both sexes were selected for this study. In the present study sample size was equally divided among male and female. ABU +ve came in 7 male children’s, out of which 3 cases were belongs to 6-10 years age group, 4 cases belongs to 11-18 years of age group. ABU +ve came in 11 female children’s, out of which 6 cases were belongs to 6-10 years age group, 5 cases belongs to 11-18 years of age group. Recent advances in research support considering ABU a separate entity from symptomatic UTI. Furthermore, in contrast to historical recommendations, recent evidence demonstrates there is minimal benefit and potential harm associated with the treatment of ABU. The current recommendation is not to treat ABU in the pediatric population, with the exception of renal transplant recipients and children undergoing urologic procedures.

Prevention of diabetes and its associated burden has become a major health issue worldwide. The present study was undertaken to assess the changes in insulin sensitivity and endothelial dysfunction well before the onset of diabetes in population with positive family history for diabetes. The objectives of the study is to estimate the levels of serum Adiponectin, Visfatin, Insulin, HOMA IR and platelet derived microparticles P-selectin levels in offspring of type 2 Diabetes mellitus. The healthy volunteers who are aged between 18- 22 years of either sex, were selected based on their family history of diabetes. The study showed a significant decrease in serum Adiponectin and increase in serum Visfatin, Insulin, HOMA IR & P-selectin levels in the offspring of type 2diabetes. The Adiponectin showed a negative correlation with Visfatin, P selectin, Insulin & HOMA IR. Genetic predisposition for diabetes may influence adipocytokine levels which might play a key role in developing diabetes in near future.

Acute appendicitis is one of the most common surgical cause of acute abdomen with life time risk of 7%. A 5-year study was conducted and it comprised of all the surgically resected appendices submitted to department of pathology, AlAmeen medical college, Bijapur. The study analysed various histopathological diagnoses, demographic profile and the rates of negative appendectomy. Total 777 cases were analysed, among them 392 were females and 385 were male, highest number of cases were seen in first and second decades of the life. It was found that acute appendicitis was more common in females and incidence of recurrent appendicitis is slightly higher in males. 18% of acute suppurative appendicitis was seen and 23 cases of acute eosinophilic appendicitis was noted. In present study, 25.7% of cases with faecolith in the lumen of appendix was noted. Parasitic infestation can cause blockade of the lumen leading to appendicitis. In our study only 2 (0.26%) cases had a parasitic infestation and enterobius vermicularis was the parasite identified in both the cases. The percentage of negative appendicectomy in our study was 5.15%. Negative appendicectomy was higher in females (62.5%) compared to males. Thus, in present study recurrent appendicitis was more common than the acute appendicitis, maximum number of cases were in the age group of first and second decades of the life, faecoliths considered very common cause of appendicitis was noted only in 25.7% and negative appendicectomy was more common among the females.

Children represent proof of manhood or womanhood in the society. The right of the child to birth registration is a prerequisite obligation any parents owe to the child after birth. Birth registration of a child is a fundamental right recognized under international law as well as domestic legislations in most civilized nations under pain of sanctions for non-compliance. The paper took an eagle eye view on the child rights to birth registration in the Cameroonian legal system. The paper also examines the need for birth registration and the socio-legal implications for non registration of child birth in Cameroon and concludes with some robust recommendations for policy formulation which it effectively implemented, will go a mile stone to guarantee the protection of birth registration of a child in Cameroon.

The essential step in the assessment of patients for a probable bleeding disorder is to evaluate the severity of bleeding symptoms. To improve the compilation and precision of the patients with history of bleeding symptoms, several Bleeding Assessment Tools (BAT) have been anticipated. A structured questionnaire was approved by the ISTH/SSC-BAT together in year 2010. In our study, data from 99 normal adults (42 females and 57 males) from Uttarakhand were analysed this score (ISTH/SSC- BAT). Mean age of the adult population was 29 year. Normal range obtained were 0–3, 0–5 for males and female respectively after removing the outliers. The median BAT score was 0 in adult males and 1 in adult females. This information may now be used to evaluate the history of bleeding symptoms as a normal or abnormal in the state of Uttarakhand. We aim to standardize this score system in the population of Uttarakhand in our study and improve diagnostic accuracy at a low cost and grass root level.

Background: Prevalence of Acute Myocardial Infarction (AMI) in younger age is increasing in worldwide and it has been reported that 60% of AMI in young age is due to genetic causes. SNP inPAI-1 4G/5G plays major role and there is a need to authenticate its effectiveness and sensitivity. The aim of this study is to ascertain SNP in PAI-1 (4G/5G) as an independent biochemical marker for the South Indian young AMI patient’s less than 45 yearsand to find its association with other risk factors of AMI. Methodology: This cross sectional study subjects includes40 Patients aged less than 45 years with AMI withtypical chest pain, ST Elevation in ECG and a rise in serum CK-MB, without any other known risk factorsand age and sex matched 40 control. ARMS-PCR was done with separated DNA. Remaining Serum was used to analyze Urea, HDL, CK-MB and other factors. Finally statistical analysisis done using SPSS-20.0. Result: Statistical analysis showed significant variation of SNP inPAI-1(P ≤ 0.001) between patients and controls. Further, positive significant changeswere observed between patients and controls in Serum Urea: P ≤ 0.001, Serum Glucose: P ≤ 0.04, Serum AST: P ≤ 0.001, Serum CK-MB: P ≤ 0. 001. A significant inverse association was observed in SNP of PAI-1 and Serum HDL. Conclusion: This study confirms the independent association between STEMI and the 4G/5G allele polymorphism among South Indian euthenics and an inverse association of 4G/5G polymorphism with Serum HDL-cholesterol levels.

Frozen section provides a rapid diagnosis intra or perioperatively that guides the surgeon to make a therapeutic decision for the patient’s health benefit. The comparison between the frozen section diagnosis and permanent section diagnosis is an integral part of quality assurance in surgical pathology. This study was performed to assess the diagnostic accuracy of frozen section at different anatomic sites assuming histopathology as a gold standard. This prospective cross sectional study was performed in the Pathology laboratory adjoining the operation theatre and Department of Pathology S.M.S Medical College and Hospital, Jaipur, during a period of 2 years from January 2017 to December 2018. The results of 170 cases of frozen section were compared with their permanent section diagnosis and analysed. A total of 224 frozen section specimens from 170 cases were studied. The diagnoses were deferred in 4 (1.79%) specimens. Out of remaining 220 specimens, the concordant and discordant diagnostic frequencies were 215 (95.98%) and 5 (2.23%) respectively. Discrepancies were mainly related to misinterpretation, sampling and technical errors. The overall diagnostic accuracy was 97.73%. The sensitivity, specificity, positive predictive value and negative predictive value were 92.68%, 98.88%, 95% and 98.33% respectively. The average turn-around time calculated was 20 minutes. Our study concurred that the frozen section is a rapid, reliable and an accurate technique to guide the surgeons in deciding the best therapeutic approach for the patients. The accuracy rate can be further improved by regular monitoring of frozen section performance.

Primary leiomyosarcoma of the broad ligament is an extremely rare tumor with very few cases reported in literature. We herein report a case of postmenopausal lady, diagnosed pre-operatively on ultrasound and CT as a degenerated fibroid/ ovarian tumor. Post operatively histopathological diagnosis proved to be a leiomyosarcoma. The patient was treated with adjuvant radiotherapy with a dose schedule of 50 Gy in 25 fractions over 5 weeks. Patient is on monthly follow up since 6 months with no complaints

Remittance is one of the key locomotives of economic growth and poverty reduction in developing countries because it serves as development finance needed for investment purposes. This study sheds new light on this question by examining the impact of remittances on private investment in Nigeria. Data on remittance inflow in Nigeria was retrieved from World Development indicator. Error correction and Ordinary least squares is applied for this purpose. The result reveals that remittances increase the rate of private investment in Nigeria and the previous investment is a determinant of the current investment. It is therefore recommended amongst others remittance-receiving households should be encouraged to invest remittances in small and medium scale enterprises rather than use it for the consumption of goods and services.