The profunda femoris artery is very important branch of femoral artery supplying the thigh. One of its important branches is medial circumflex femoral artery. Knowledge about variation in its origin is important for the surgeons and radiologists. The present study was conducted in 50 embalmed cadavers in the department of Anatomy, Stanley Medical College. The medial circumflex femoral arteries were seen originating from profunda femoris artery in 84 %. In 16% medial circumflex femoral arteries were seen originating from the femoral artery at the same level of profunda femoris artery.